Endocrine News and Research

RSS

Simple, at-home treatment for jet lag

A simple, at-home treatment -- a single light box and the over-the-counter drug melatonin -- allows travelers to avoid jet lag by resetting their circadian body clock before crossing several time zones, according to new research being published in The Endocrine Society's Journal of Clinical Endocrinology and Metabolism.

3 Nov 2005

First study to confirm the benefit of anti-angiogenic therapy in patients with breast cancer

Results from the first and only interim analysis of an important trial assessing the potential of Herceptin (trastuzumab) to improve disease-free survival (DFS) in HER-2 positive breast cancer patients after adjuvant chemotherapy, have shown that Herceptin affords a significant survival advantage.

1 Nov 2005

Testosterone may improve women's sex lives after menopause

The addition of testosterone to hormone therapy in women after menopause enhances their sexual function. However, it may also reduce HDL cholesterol (the "good" cholesterol) in women, according to a systematic review of current evidence.

23 Oct 2005

Menin is a key player in the development of some forms of acute leukemia

Tumor-suppressor proteins work to inhibit tumor growth in our bodies and when they win, they spare us a battle with cancer. But one such protein, menin, appears to have a split personality.

20 Oct 2005

Distress caused by hot flushes seriously under-played

A study by UK researchers of over 200 breast cancer patients receiving hormone treatments such as tamoxifen has found that nearly two-thirds would prefer to take a tablet daily and around a quarter would prefer a monthly injection, given that both treatments would be equally effective and have similar side-effects.

19 Oct 2005

Consistently, African-Americans have been found to have worse health outcomes than whites

Ninety-five percent of older African-American clinic patients reported at least some exposure to racism during their lives in a study by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.

19 Oct 2005

Gastric bypass surgery may not be the most effective surgery in producing weight loss

"Overall, we found that patients who elect to have duodenal switch end up slimmer than those who choose gastric bypass," says Dr. Gladys W. Strain, director of research for bariatric surgery at NewYork-Presbyterian/Weill Cornell and associate research professor of nutrition in surgery at Weill Medical College of Cornell University.

16 Oct 2005

PCBs found widely in the environment and absorbed in the diet - may damage sperm

Research by an European Union-supported international team of scientists has shown that polychlorinated biphenyls (PCBs) - synthetic organic chemicals found widely in the environment and absorbed in the diet - may damage sperm.

13 Oct 2005

Findings increase understanding of how an organism's body size is determined and how the speed of its development is controlled

In particular, the work sheds light on the molecular and cellular pathways that act to convey information about a growing organism's size, as well as on pathways that use that information to correctly time critical transitional events during development.

26 Sep 2005

Increlex - first major innovation in 20 years for the treatment of growth failure

Rush University Medical Center is participating in a clinical trial to evaluate the potential benefit of the first major innovation in 20 years for the treatment of growth failure.

26 Sep 2005

Tobacco industry hindered federal and international regulations on pesticide use

The tobacco industry coordinated cross-industry campaigns to delay and weaken federal and international regulations on pesticide use, according to new findings by University of California - San Francisco (UCSF) researchers.

26 Sep 2005

Methoxychlor (MXC), a common insect pesticide may lead to reduced fertility in women

Methoxychlor (MXC), a common insect pesticide used on food crops, may interfere with proper development and function of the reproductive tract, leading to reduced fertility in women, researchers at Yale School of Medicine write in the August issue of Endocrinology.

19 Sep 2005

Methoxychlor (MXC) may interfere with proper development and function of the reproductive tract, leading to reduced fertility in women

The researchers found that MXC, which was manufactured as a safer replacement for the now-banned DDT, alters the estrogen-regulated gene Hoxa10 in the reproductive tract and reduces the ability of the uterus to support embryo implantation. The researchers used mice and then human cell lines to confirm their findings.

7 Sep 2005

New ways to enhance or block fertilization

Researchers have capitalized on the unique properties of a sperm cell to follow cell membrane fusion as it occurs during fertilization, tracking the full cascade of events for the first time. The findings could reveal new ways to enhance or block fertilization, as well as how to control the secretion of neurotransmitters and hormones such as insulin.

6 Sep 2005

SH2-B enhances brain's leptin sensitivity - may lead to clues for treatment of obesity and diabetes

What do laboratory mice at the University of Michigan Medical School have in common with millions of overweight Americans? Like many of us, these mice just can't stop eating.

18 Aug 2005

Researchers find drug targets for treating metabolic syndrome

Ongoing studies by researchers at UT Southwestern Medical Center and other institutions have uncovered the biochemical basis of many of the factors contributing to what is known as the metabolic syndrome, suggesting potential new drug targets for treating the condition.

11 Aug 2005

Switching treatment to the drug anastrozole after two years of tamoxifen is beneficial for women with early breast cancer

Switching treatment to the drug anastrozole after two years of tamoxifen can improve eventfree survival for postmenopausal women with early breast cancer, concludes a study in this week’s issue of The Lancet.

4 Aug 2005

Pedometers motivate walkers

Need motivation to walk 10,000 steps? Get a pedometer, says University of Tennessee professor Dixie Lee Thompson.

2 Aug 2005

$New protective drugs called bisphosphonates reduce pain and fractures in metastatic breast cancer$

New protective drugs called bisphosphonates reduce pain and fractures in metastatic breast cancer

When breast cancer spreads to bones, relatively new protective drugs called bisphosphonates can reduce skeletal damage, says a new systematic review of previous studies. While the new treatment approach does not improve survival rates, it can minimize disabling fractures, spinal cord compression and pain.

19 Jul 2005

Potential use of NH neurotransmitters as novel source for psychiatric drugs

Physiologists and medical researchers have long recognized the important endocrine roles played by the pituitary hormones oxytocin (OT) and vasopressin (VP) on peripheral systems in lactation, uterine contraction and urine concentration.

19 Jul 2005

Endocrine News and Research

Simple, at-home treatment for jet lag

First study to confirm the benefit of anti-angiogenic therapy in patients with breast cancer

Testosterone may improve women's sex lives after menopause

Menin is a key player in the development of some forms of acute leukemia

Distress caused by hot flushes seriously under-played

Consistently, African-Americans have been found to have worse health outcomes than whites

Gastric bypass surgery may not be the most effective surgery in producing weight loss

PCBs found widely in the environment and absorbed in the diet - may damage sperm

Findings increase understanding of how an organism's body size is determined and how the speed of its development is controlled

Increlex - first major innovation in 20 years for the treatment of growth failure

Tobacco industry hindered federal and international regulations on pesticide use

Methoxychlor (MXC), a common insect pesticide may lead to reduced fertility in women

Methoxychlor (MXC) may interfere with proper development and function of the reproductive tract, leading to reduced fertility in women

New ways to enhance or block fertilization

SH2-B enhances brain's leptin sensitivity - may lead to clues for treatment of obesity and diabetes

Researchers find drug targets for treating metabolic syndrome

Switching treatment to the drug anastrozole after two years of tamoxifen is beneficial for women with early breast cancer

Pedometers motivate walkers

New protective drugs called bisphosphonates reduce pain and fractures in metastatic breast cancer

Potential use of NH neurotransmitters as novel source for psychiatric drugs

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest News