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New process for altering ingredients in sunscreen enables the body to produce vitamin D

New process for altering ingredients in sunscreen enables the body to produce vitamin D

For the first time researchers have developed a process for altering the ingredients in a sunscreen that does not impact its sun protection factor (SPF), but does allow the body to produce vitamin D. The findings, published in the peer reviewed journal PLOS ONE, has led to the production of a new sunscreen called Solar D. [More]
Maternal diet during pregnancy and lactation leads to epigenetic changes in offspring

Maternal diet during pregnancy and lactation leads to epigenetic changes in offspring

As the study shows, a high-fat diet during pregnancy and lactation leads to epigenetic changes in the offspring. These changes affect metabolic pathways regulated by the gut hormone GIP, whereby the adult offspring are more susceptible to obesity and insulin resistance, the precursor to type 2 diabetes. Similar mechanisms cannot be ruled out in humans, according to Pfeiffer. [More]
Researchers test new concept in type 2 diabetes patients going into remission

Researchers test new concept in type 2 diabetes patients going into remission

Remission is well-known as the goal in cancer treatment but scientists are discovering it's also an exciting possibility for those with type 2 diabetes. [More]
Study focuses on parents' perceptions of risks, benefits of treating children with short stature

Study focuses on parents' perceptions of risks, benefits of treating children with short stature

A new study led by pediatric endocrinologist Adda Grimberg, M.D., of The Children's Hospital of Philadelphia, proposes to reframe the debate. "We set out to answer a new question," said Grimberg. "What are the factors, perceived or real, that drive some families to seek medical care for short stature?" [More]
Mayo Clinic researchers report national trend toward overtesting HbA1C levels in diabetes patients

Mayo Clinic researchers report national trend toward overtesting HbA1C levels in diabetes patients

In a study released online today in The BMJ, researchers from Mayo Clinic report a national trend toward overtesting glycated hemoglobin (HbA1C) levels in adult patients with Type 2 diabetes. [More]
Researchers begin landmark clinical study to restore normal insulin secretion in people with type 1 diabetes

Researchers begin landmark clinical study to restore normal insulin secretion in people with type 1 diabetes

Investigators at Montreal's Lady Davis Institute at the Jewish General Hospital and McGill University Health Centre have announced the start of a landmark clinical study aimed at restoring normal insulin secretion in people with longstanding type 1 diabetes. [More]
Tips to help people living with diabetes survive the holiday season

Tips to help people living with diabetes survive the holiday season

The holidays are a time to gather with family and friends. It's also a season to indulge in all of your favorite holiday foods and drink. For people living with diabetes, keeping blood sugars under control is often a challenge, but the holiday season can bring additional hurdles. [More]
Mayo Clinic investigators discover novel mechanism linked to diabetes risk

Mayo Clinic investigators discover novel mechanism linked to diabetes risk

Researchers at Mayo Clinic have discovered an unexpected effect from a gene known to increase diabetes risk. They assumed that the specific allele in the gene TCF7L2 which increases the risk of type 2 diabetes, impairs insulin production in response to increased insulin resistance. Some slight evidence of that was found, but more significantly the researchers discovered that this variant impaired a person's ability to balance blood sugar (glucose) by suppressing glucagon - the hormone that raises the level of glucose in the bloodstream. [More]
Two genetic variants interact to alter the brain responses to high-calorie foods

Two genetic variants interact to alter the brain responses to high-calorie foods

For the first time, researchers have identified two genetic variants that interact to alter the brain responses to high-calorie foods, a tie that could aid in the development of targeted treatments for obesity and overweight. Researchers at Imperial College London led by Tony Goldstone, MD, PhD, of Consultant Endocrinologist, found that two gene variants - FTO and DRD2 - influenced activity in the brain reward system when looking at pictures of high-calorie foods. [More]
Transition Therapeutics Ireland signs agreement for investigator-led TT701 Phase 2 clinical study

Transition Therapeutics Ireland signs agreement for investigator-led TT701 Phase 2 clinical study

Transition Therapeutics Inc. announced today that Transition Therapeutics Ireland Limited has entered into an agreement for an investigator-led clinical study of drug candidate, TT701, with Brigham and Women's Hospital. [More]
Reducing sugar intake reverses chronic metabolic diseases in children

Reducing sugar intake reverses chronic metabolic diseases in children

Reducing consumption of added sugar, even without reducing calories or losing weight, has the power to reverse a cluster of chronic metabolic diseases, including high cholesterol and blood pressure, in children in as little as 10 days, according to a study by researchers at UC San Francisco and Touro University California. [More]
ARC Telehealth System allows fertility patients connect with medical professionals through mobile devices

ARC Telehealth System allows fertility patients connect with medical professionals through mobile devices

ARC Fertility today announced its Telehealth System, designed to help fertility patients connect with medical professionals via mobile devices to improve communication, speed treatment and increase quality of care. [More]
IU investigators find how cancer-induced bone destruction triggers skeletal muscle weakness

IU investigators find how cancer-induced bone destruction triggers skeletal muscle weakness

Cancer researchers at Indiana University and their colleagues have discovered how cancer-induced bone destruction causes skeletal muscle weakness. [More]
Endocrine Society issues Clinical Practice Guideline on treatment of menopausal symptoms

Endocrine Society issues Clinical Practice Guideline on treatment of menopausal symptoms

The Endocrine Society today issued a Clinical Practice Guideline (CPG) on identifying women who are candidates for treatment of menopausal symptoms and selecting the best treatment options for each individual. [More]
U.S 2nd Annual Obesity Summit: 35 major U.S. health societies see how they can treat obesity

U.S 2nd Annual Obesity Summit: 35 major U.S. health societies see how they can treat obesity

Representatives from 35 major health and medical organizations including, the American Diabetes Association (ADA), American Medical Association (AMA), American Heart Association (AHA), American Academy of Orthopaedic Surgeons (AAOS), and American Society of Clinical Oncology (ASCO) convened for a second annual summit in Chicago to identify opportunities for collaboration in treating obesity. “The National Obesity Summit on the Provision of Care for the Obese Patient” was hosted by the American Society for Metabolic and Bariatric Surgery (ASMBS). [More]
Study explores effectiveness of frontline treatments for couples with unexplained infertility

Study explores effectiveness of frontline treatments for couples with unexplained infertility

A breast cancer drug with promise for improving the chance that couples with unexplained infertility can have a baby without increasing their risk of multiple births apparently does not deliver, according to a comparative study. [More]
IUPUI awarded grant to develop breathalyzer-type device for detecting hypoglycemia in diabetes people

IUPUI awarded grant to develop breathalyzer-type device for detecting hypoglycemia in diabetes people

A multidisciplinary team of researchers at Indiana University-Purdue University Indianapolis has been awarded a $738,000 National Science Foundation grant to develop a breathalyzer-type device to detect the onset of hypoglycemia, or low blood sugar episodes, in people with diabetes. [More]
Population health study examines real-world osteoporosis treatment patterns

Population health study examines real-world osteoporosis treatment patterns

A statewide study has found that from 2005 to 2012, fewer than a quarter of men and women with documentation of osteoporosis or fragility fracture, conditions for which national guidelines would recommend treatment for osteoporosis, actually received that treatment. [More]
Researchers discover new gene that could be a potential therapeutic target for muscle wasting

Researchers discover new gene that could be a potential therapeutic target for muscle wasting

It is estimated that half of all cancer patients suffer from a muscle wasting syndrome called cachexia. Cancer cachexia impairs quality of life and response to therapy, which increases morbidity and mortality of cancer patients. Currently, there is no approved treatment for muscle wasting but a new study from the Research Institute of the McGill University Health Centre and University of Alberta could be a game changer for patients, improving both quality of life and longevity. [More]
Education intervention can improve physicians’ understanding of transgender issues

Education intervention can improve physicians’ understanding of transgender issues

The term "transgender" has made its way into mainstream media thanks to Caitlyn Jenner, previously known as Bruce Jenner, who came out as a transgender woman earlier this year. [More]
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