Endoplasmic reticulum (ER) News and Research

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Reduced incidence of invasive breast cancer with Raloxifene among women at increased coronary risk

Women who took raloxifene were less likely to develop invasive estrogen-receptor (ER) positive breast cancer compared with women who did not, according to data from a randomized controlled trial published online June 10 in the Journal of the National Cancer Institute. The drug did not reduce the risk of non-invasive cancer or invasive ER-negative cancers.

11 Jun 2008

New insight into the genetics of Lou Gehrig's disease

An upcoming paper from Drs. Hidenori Ichijo and Hideki Nishitoh (The University of Tokyo) and colleagues lends new and valuable insight into the genetics of ALS.

1 Jun 2008

Estrogen drives distinct, aggressive prostate cancer

Using a breakthrough technology, researchers led by a Weill Cornell Medical College scientist have pinpointed the hormone estrogen as a key player in about half of all prostate cancers.

28 May 2008

Washington Post series examines childhood obesity

An "epidemic of obesity" is "compromising the lives of millions of American children" and is "expected to add billions of dollars to the U.S. health care bill," the Washington Post reports.

20 May 2008

Aspirin a day cuts risk of common breast cancer

Scientists in the U.S. say an aspirin a day may afford women some protection against the most common type of breast cancer, estrogen receptor or ER-positive breast cancer.

30 Apr 2008

Aspirin and other NSAIDs could lower the risk of breast cancer

Taking aspirin on a daily basis may lower women's risk of a particular type of breast cancer, according to results published in BioMed Central's open access journal Breast Cancer Research.

30 Apr 2008

Breast cancer subtypes are different diseases

There is a biological distinction between breast cancers that depend on hormones and those that do not, according to research published in PLoS Genetics (Friday).

26 Apr 2008

Coffee protects some women against breast cancer

Depending on which variant of a certain gene a woman has, a coffee consumption rate of at least two-three cups a day can either reduce the total risk of developing breast cancer or delay the onset of cancer. This is shown in new research from Lund University and Malmo University in Sweden.

24 Apr 2008

Tredaptive and Janumet recommended for approval in European Union

Food and Drug Administration (FDA) is currently reviewing the combination of extended release (ER) niacin and laropiprant under the trademark Cordaptive (ER niacin/laropiprant). The CHMP recommendation does not apply to regulatory decisions by the FDA and no inferences should be made about pending FDA regulatory actions based on the recommendation of the CHMP.

24 Apr 2008

Cancer prevention

Tapping into a growing body of knowledge about the origins and progression of cancer, researchers are now developing and testing new preventive therapies to stop it in its tracks.

15 Apr 2008

Biomarkers allow doctors to match therapy to patient

Genetic variations ensure that no two people are exactly alike, nor are their cancers.

13 Apr 2008

Cocaine can cause symptoms of a heart attack

According to new research from the U.S., using cocaine can cause chest pain and other symptoms similar to a heart attack.

19 Mar 2008

Survival mechanism of T lymphocytes uncovered

When an individual is challenged by a virus, a bacterium or any other infectious agent, several classes of white blood cells are being activated in order to fight the invasion.

19 Mar 2008

New study proves Neoteric's BloodTrack increases hospital efficiency

Neoteric Technology Ltd. announced today that a new study released in this month's American Association of Blood Banks (AABB) Journal of Transfusion proves that dramatic time and cost savings can be achieved by hospitals that implement BloodTrack OnDemand.

11 Mar 2008

Estradiol hormone protects against hearing loss

The "female sex hormone" estradiol is present in both men and women, and is generated from testosterone in men by the protein aromatase.

4 Mar 2008

Breast cancer subtypes linked to survival from secondary brain tumors

Screening breast cancers for three receptors could help doctors predict the likely survival of patients with brain metastases.

28 Feb 2008

Benefit of removal of the ovaries differs between women with BRCA1 and BRCA2 mutations

The surgical removal of the ovaries has been widely adopted as a cancer-risk-reducing strategy for women with either BRCA1 or BRCA2 mutations.

12 Feb 2008

Antiepileptic drug warning from FDA

The U.S. Food and Drug Administration today issued new information to health care professionals to alert them about an increased risk of suicidal thoughts and behaviors (suicidality) in patients who take drugs called antiepileptics to treat epilepsy, bipolar disorder, migraine headaches, and other conditions.

5 Feb 2008

7,000 pediatric ER visits linked to cough, cold medication use

An estimated 7,000 patients, ages 11 and younger, are treated in hospital emergency departments (ED) each year largely from unsupervised ingestions of cough and cold medications.

4 Feb 2008

Event to address the effects of breast cancer on black women

Although the overall incidence of breast cancer in black women is lower than in white women, black women are more likely to die from breast cancer than their white counterparts.

4 Feb 2008