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Concordia Healthcare enters into definitive agreement to acquire Donnatal

Concordia Healthcare enters into definitive agreement to acquire Donnatal

Concordia Healthcare Corp., announced today that it has entered into a definitive agreement to acquire Donnatal®, an adjunctive therapy in the treatment of irritable bowel syndrome ("IBS") and acute enterocolitis, from a privately held specialty pharmaceutical company carrying on business as Revive Pharmaceuticals ("Revive Pharmaceuticals"). [More]

Researchers identify marker to find infants at risk for life-threatening bowel infection

Many premature infants suffer a life-threatening bowel infection called necrotizing enterocolitis (NEC). [More]

Research findings may lead to better care for premature infants at risk of necrotizing enterocolitis

Many premature infants suffer a life-threatening bowel infection called necrotizing enterocolitis (NEC). [More]

Risk factor for life-threatening bowel infection in premature infants identified

Many premature infants suffer a life-threatening bowel infection called necrotizing enterocolitis (NEC). [More]
Perinatal probiotic supplements do not prevent childhood asthma

Perinatal probiotic supplements do not prevent childhood asthma

There is insufficient evidence to support the use of probiotic supplements during pregnancy or infancy to prevent the development of asthma in infants, Canadian researchers report. [More]
BioGaia plans to invest in first phase of project aimed at developing drug for NEC

BioGaia plans to invest in first phase of project aimed at developing drug for NEC

The board of BioGaia has decided to invest in the first phase of a long-term project aimed at developing a drug with rigorous hygiene, analysis and documentation requirements, to treat the highly fatal disease Necrotising Enterocolitis, which affects premature infants. [More]
Low birth weight infants more susceptible to invasive infections

Low birth weight infants more susceptible to invasive infections

Low birth weight infants are host to numerous microorganisms immediately after birth, and the microbiomes of their mouths and gut start out very similar but differentiate significantly by day 15 according to a study published in mBio-, the online open-access journal of the American Society for Microbiology. [More]
Breast milk purchased over Internet contained bacteria that can cause illness in infants

Breast milk purchased over Internet contained bacteria that can cause illness in infants

Results from a study led by researchers at Nationwide Children's Hospital found more than three-fourths of breast milk samples purchased over the Internet contained bacteria that can cause illness, and frequently exhibited signs of poor collection, storage or shipping practices. [More]
Studies reveal potential of HB-EGF in protecting intestines from diverse types of injury

Studies reveal potential of HB-EGF in protecting intestines from diverse types of injury

It's not often that one treatment offers therapeutic potential for multiple conditions. However, after more than two decades of research, Gail Besner, MD, principal investigator for the Center for Perinatal Research and pediatric surgeon for the Department of Pediatric Surgery at Nationwide Children's Hospital, and her team have found that this may just be the case with HB-EGF, or heparin-binding EGF-like growth factor. [More]

Breast milk might prevent premature babies from deadly intestinal condition

An ingredient that naturally occurs in breast milk might be used to prevent premature babies from developing a deadly intestinal condition that currently is largely incurable, according to researchers at the University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh of UPMC in this week's online early edition of the Proceedings of the National Academy of Sciences. [More]
Study investigates new way to treat necrotizing enterocolitis

Study investigates new way to treat necrotizing enterocolitis

Stem cells taken from amniotic fluid were used to restore gut structure and function following intestinal damage in rodents, in new research published in the journal Gut. [More]
Probiotics shows promise in reducing both incidence and severity of necrotizing enterocolitis

Probiotics shows promise in reducing both incidence and severity of necrotizing enterocolitis

"Good" bacteria that live in our intestines have been linked with a variety of health benefits, from fighting disease to preventing obesity. In a new study, Kriston Ganguli of Massachusetts General Hospital for Children and Harvard Medical School and her colleagues have discovered another advantage to these friendly microscopic tenants: Chemicals secreted by good bacteria that typically live in the intestines of babies could reduce the frequency and severity of a common and often-lethal disease of premature infants. [More]
Parenteral nutrition safety: an interview with Dr. Phil Ayers, A.S.P.E.N PN Safety Task Force Chair and Dr. Peggi Guenter, Director of the American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.)

Parenteral nutrition safety: an interview with Dr. Phil Ayers, A.S.P.E.N PN Safety Task Force Chair and Dr. Peggi Guenter, Director of the American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.)

Parenteral nutrition is intravenous nutrition for patients who are unable to eat or be tube fed. It is used with more than 300,000 patients per year - a quarter of whom are children and newborns. [More]

Contrast agent ‘not recommended’ in premature neonates

Premature neonates who are given oral Gastrografin immediately after birth do not pass meconium more quickly than others, study findings suggest. [More]
Breast milk banks: an interview with Dr. Pieter Koorts

Breast milk banks: an interview with Dr. Pieter Koorts

The available literature clearly demonstrates that in almost all circumstances a mother’s own breast milk is the ideal food for her infant. This is particularly important for preterm infants. Preterm infants are babies born before 37 completed weeks of pregnancy. [More]
NICE decides to recommend Bristol-Myers Squibb’s YERVOY for treatment of advanced melanoma

NICE decides to recommend Bristol-Myers Squibb’s YERVOY for treatment of advanced melanoma

Bristol-Myers Squibb Company is pleased to announce that today the National Institute of Health and Clinical Excellence (NICE) has decided to recommend YERVOY (ipilimumab), which is approved in the European Union for the treatment of previously-treated metastatic (advanced) melanoma, within the Final Appraisal Determination (FAD). [More]

Study shows how NCH guidelines improve quality of life for extremely premature infants

For the last decade, prematurity has been the leading cause of infant mortality in the United States. As a result of prematurity many infants enter this world too early with a small chance of survival. In order to help treat these extremely premature infants, physicians at Nationwide Children's Hospital developed a set of guidelines tailored to meet the needs of these tiny infants, some born up to four months early. [More]

Study sheds light on risks of fetal position at the time of premature birth

Breech births increase the risk of complications for the mother and baby when the amniotic sac ruptures early. [More]

FOS prebiotic could replace intravenous feeding in pediatric patients with intestinal failure

Adding the right prebiotic to the diets of pediatric patients with intestinal failure could replace intravenous feeding, says a new University of Illinois study. [More]

Transfused blood age does not impact outcomes in premature babies

Using fresh red blood cells for premature babies who need blood transfusions does not improve outcomes over use of standard blood bank donations, show study findings published in JAMA. [More]