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OGT releases new application note detailing performance of two DNA labelling kits

Oxford Gene Technology, The Molecular Genetics Company, has released a new application note detailing the technical evaluation of two DNA labelling kits, where OGT’s CytoSure Genomic DNA Labelling Kits were found to be quicker and more accurate than a leading alternative.

From Oxford Gene Technology 23 Apr 2014

Cedars-Sinai researchers to receive $8M grant to fund Phase II clinical trial of experimental drug for stroke

Cedars-Sinai stroke intervention researchers have been informed that the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, will award an $8 million grant to fund a multicenter Phase II clinical trial of an experimental drug for stroke.

22 Apr 2014

Neoadjuvant targeted treatment shows feasibility for limited clear-cell RCC

Treating patients with nonmetastatic clear-cell renal cell carcinoma with the tyrosine kinase inhibitor axitinib could not only prevent disease progression, but also shrink tumours before surgery, show the results of a phase II trial.

22 Apr 2014

Study explains biological processes of malignant cancer cells

Cancer cells may be known for their uncontrollable growth and spread, but they also differ from normal tissue in another manner: how they produce energy.

22 Apr 2014

Researcher explores public perceptions related to newborn screening programs

While 94 per cent of Canadians surveyed said they would participate in public health programs that screen newborns for a specific number of genetic conditions, only 80 per cent said they would be willing to participate in screening that would sequence their newborns' genomes.

22 Apr 2014

SIRT1 protein necessary for telomere elongation and genome integrity during cell reprogramming

Cell reprogramming converts specialised cells such as nerve cells or skin cells towards an embryonic stem cell state. This reversal in the evolutionary development of cells also requires a reversal in the biology of telomeres, the structures that protect the ends of chromosomes; whilst under normal conditions telomeres shorten over time, during cell reprogramming they follow the opposite strategy and increase in length.

22 Apr 2014

Penn study clarifies action of potential new class of pain relievers that may benefit and not hurt heart

Nonsteroidal antinflamatory drugs (NSAIDs) that block an enzyme called COX-2 relieve pain and inflammation but can cause heart attacks, stroke, heart failure, and even sudden cardiac death.

22 Apr 2014

New genetic evidence strengthens link between role of dietary fats with colon cancer progression

Scientists have shown new genetic evidence that could strengthen the link between the role of dietary fats with colon cancer progression.

22 Apr 2014

Synageva announces publication of LAL Deficiency review in Atherosclerosis

Synageva BioPharma Corp., a biopharmaceutical company developing therapeutic products for rare diseases, today announced the publication of an overview of lysosomal acid lipase deficiency (LAL Deficiency) in the online version and an upcoming print edition of Atherosclerosis, the official journal of the European Atherosclerosis Society.

21 Apr 2014

Scientists lay groundwork for understanding immune responses in Lyme disease patients

A team of scientists led by Johns Hopkins and Stanford University researchers has laid the groundwork for understanding how variations in immune responses to Lyme disease can contribute to the many different outcomes of this bacterial infection seen in individual patients. A report on the work appears online April 16 in PLOS One.

21 Apr 2014

New device uses space-tested concept of capillary flow to diagnose infectious diseases

A new medical-testing device is being prepped to enter the battle against infectious disease. This instrument could improve diagnosis of certain diseases in remote areas, thanks in part to knowledge gained from a series of investigations aboard the International Space Station on the behavior of liquids. The device uses the space-tested concept of capillary flow to diagnose infectious diseases such as HIV/AIDS and tuberculosis.

20 Apr 2014

Probiotics usage proves ineffective for infant colic symptoms

Colic affects about one in five infants in the United States annually and accounts for numerous pediatric visits during the first several months after birth.

18 Apr 2014

Drug used to treat TB may also act against various infections, says study

A drug under clinical trials to treat tuberculosis could be the basis for a class of broad-spectrum drugs that act against various bacteria, fungal infections and parasites, yet evade resistance, according to a study by University of Illinois chemists and collaborators.

18 Apr 2014

Scientists develop microbicide gel that prevents transmission of multiple STIs in vagina/rectum in animals

Population Council scientists and their partners have found that their proprietary microbicide gel is safe, stable, and can prevent the transmission of multiple sexually transmitted infections (STIs) in both the vagina and rectum in animals: HIV, herpes simplex virus 2 (HSV-2), and human papillomavirus (HPV).

18 Apr 2014

Agios begins AG-348 Phase 1 study to treat PK deficiency

Agios Pharmaceuticals, Inc., a leader in the fields of cancer metabolism and inborn errors of metabolism (IEM), today announced dose administration of AG-348 in a Phase 1 study in healthy volunteers.

18 Apr 2014

New research may help scientists develop treatments or vaccines for Dengue fever

Two recent papers by a University of Colorado School of Medicine researcher and colleagues may help scientists develop treatments or vaccines for Dengue fever, West Nile virus, Yellow fever, Japanese encephalitis and other disease-causing flaviviruses.

18 Apr 2014

Alcresta signs agreement with CFFT to support nutritional status of people with cystic fibrosis

Alcresta, a leading medical nutrition company developing innovative enzyme-based products for individuals with unique nutritional needs battling acute conditions or chronic diseases, today announced the company has signed an agreement with Cystic Fibrosis Foundation Therapeutics (CFFT) to accelerate the development of Alcresta's enzyme-based point-of-care products to support the nutritional status of people with cystic fibrosis (CF).

17 Apr 2014

Boehringer grants volasertib 'orphan drug designation' for treatment of patients with AML

Boehringer Ingelheim announced today that the US Food and Drug Administration (FDA) and the European Commission have granted volasertib* 'orphan drug designation' for the treatment of patients with acute myeloid leukaemia (AML).

17 Apr 2014

Professor from INRS receives NIH grant to explore biomedical potential in field of oncology

Professor Nicolas Doucet of the Centre INRS-Institut Armand-Frappier has just received a research grant from the National Institutes of Health (NIH) in the amount of nearly US$600,000. The 5-year grant is to pursue cutting-edge research in the workings of tiny proteins called RNases and to explore their biomedical potential in the field of oncology as well as in inflammation and asthma.

17 Apr 2014

Scientists report new approach to restore penicillin's combat effectiveness against bacterial infections

Penicillin, one of the scientific marvels of the 20th century, is currently losing a lot of battles it once won against bacterial infections. But scientists at the University of South Carolina have just reported a new approach to restoring its combat effectiveness, even against so-called "superbugs."

16 Apr 2014

Enzyme News and Research

OGT releases new application note detailing performance of two DNA labelling kits

Cedars-Sinai researchers to receive $8M grant to fund Phase II clinical trial of experimental drug for stroke

Neoadjuvant targeted treatment shows feasibility for limited clear-cell RCC

Study explains biological processes of malignant cancer cells

Researcher explores public perceptions related to newborn screening programs

SIRT1 protein necessary for telomere elongation and genome integrity during cell reprogramming

Penn study clarifies action of potential new class of pain relievers that may benefit and not hurt heart

New genetic evidence strengthens link between role of dietary fats with colon cancer progression

Synageva announces publication of LAL Deficiency review in Atherosclerosis

Scientists lay groundwork for understanding immune responses in Lyme disease patients

New device uses space-tested concept of capillary flow to diagnose infectious diseases

Probiotics usage proves ineffective for infant colic symptoms

Drug used to treat TB may also act against various infections, says study

Scientists develop microbicide gel that prevents transmission of multiple STIs in vagina/rectum in animals

Agios begins AG-348 Phase 1 study to treat PK deficiency

New research may help scientists develop treatments or vaccines for Dengue fever

Alcresta signs agreement with CFFT to support nutritional status of people with cystic fibrosis

Boehringer grants volasertib 'orphan drug designation' for treatment of patients with AML

Professor from INRS receives NIH grant to explore biomedical potential in field of oncology

Scientists report new approach to restore penicillin's combat effectiveness against bacterial infections

Biochemistry eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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