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USF Health receives $2.1M grant to study on new factors required for growth of malaria-related parasites

Animal cells similar to those of humans contain a "control room," called the centrosome, which regulates cell replication. Disrupt this core hub and you kill cell division.

24 Jan 2014

Scientists identify critical regulator of molecule involved in progression of Alzheimer’s disease

Scientists from the Florida campus of The Scripps Research Institute have identified a critical regulator of a molecule deeply involved in the progression of Alzheimer’s disease.

23 Jan 2014

New easy-to-use risk calculator helps predict heart failure patients' chances of survival

A UCLA team has developed an easy-to-use "risk calculator" that helps predict heart failure patients' chances of survival for up to five years and assists doctors in determining whether more or less aggressive treatment is appropriate.

23 Jan 2014

Scientists develop new genetic platform that yields novel antibiotic from ocean bacteria

Scientists at the University of California, San Diego have developed a new genetic platform that allows efficient production of naturally occurring molecules, and have used it to produce a novel antibiotic compound.

23 Jan 2014

Chinese and American researchers introduce new approach to gene therapy

Resistance of tumor cells toward multiple cytostatic drugs is a serious problem in cancer treatment. In the journal Angewandte Chemie, a team of Chinese and American researchers has now introduced a new approach to gene therapy that could counter this problem: The gene that codes for resistance is “silenced” through the use of an ingenious nanocomplex.

22 Jan 2014

New oral drug appears to offer hope for fighting indolent non-Hodgkin lymphoma

Slow-growing, or indolent, non-Hodgkin lymphomas are difficult to treat, with most patients relapsing repeatedly and the disease becoming increasingly resistant to therapy over time.

22 Jan 2014

Scientists identify specific enzyme essential for brain development

Scientists from the Max F. Perutz Laboratories (MFPL) of the University of Vienna and the Medical University of Vienna have identified a specific enzyme, histone deacetylase 2 (HDAC2), as essential for brain development. The findings published in Development are important to advance the development of new drugs to treat neurological diseases.

22 Jan 2014

Scientists showcase HDL nanotherapy that may provide solution to repeat heart attacks

Up to 30 percent of heart attack patients suffer a new heart attack because cardiologists are unable to control inflammation inside heart arteries - the process that leads to clots rupturing and causing myocardial infarction or stroke.

22 Jan 2014

Childhood brain cancer (ETMR/ETANTR): an interview with Dr. Nada Jabado, Department of Pediatrics at McGill University

Embryonal tumours with multilayered rosettes (ETMR) are rare, deadly brain tumours that affect mainly children below the age of 4 years. There are 300 cases reported but probably there are many more as this tumour is often misdiagnosed.

21 Jan 2014

Forest Laboratories third quarter net sales increase 24.9% to $846.8 million

Forest Laboratories, Inc., a leading, fully integrated, specialty pharmaceutical company largely focused on the United States market, announced that reported diluted earnings per share equaled $0.07 in the third quarter of fiscal 2014, compared to a reported loss per share of ($0.58) in the third quarter of fiscal 2013. The third quarter of fiscal 2014 included a $45 million charge ($28.2 million net of tax) related to Project Rejuvenate.

21 Jan 2014

European Commission approves ViiV Healthcare's Tivicay for treatment of HIV infected adults

ViiV Healthcare today announced that the European Commission has approved Tivicay (dolutegravir), an integrase inhibitor, for use in combination with other anti-retroviral medicinal products for the treatment of HIV infected adults and adolescents above 12 years of age.

21 Jan 2014

Researchers find new candidate that may help combat malaria

Two of the most urgent challenges for scientists are the battles against food shortages and infectious diseases like malaria. Unfortunately, both the herbicides used to protect plants and the anti-infectives that shield us from disease rapidly lose their effectiveness as the target organisms develop resistance. In order to benefit both fields at once, scientists tested lead compounds from agrochemical research against infectious germs as well.

21 Jan 2014

Researchers identify molecular mechanism by which cocaine alters brain's reward circuits, causes addiction

Researchers from the Icahn School of Medicine at Mount Sinai have identified a new molecular mechanism by which cocaine alters the brain's reward circuits and causes addiction.

21 Jan 2014

Gene therapy edges closer for Parkinson’s disease

Lentiviral vector-based gene therapy is well tolerated and may improve motor function in patients with Parkinson’s disease, shows an open-label study published in The Lancet.

20 Jan 2014

New technology may provide solution to high risk of repeat heart attacks, say scientists

Up to 30 percent of heart attack patients suffer a new heart attack because cardiologists are unable to control inflammation inside heart arteries — the process that leads to clots rupturing and causing myocardial infarction or stroke.

20 Jan 2014

Scientists uncover how microbiota metabolise complex dietary carbohydrates found in fruits, vegetables

We are all aware of the health benefits of "dietary fibre". But what is dietary fibre and how do we metabolise it?

20 Jan 2014

TSRI scientists use new technique to discover two antibodies that protect human cells from cold virus

Scientists at The Scripps Research Institute (TSRI) have demonstrated the power of a new drug discovery technique, which allows them to find-relatively quickly and cheaply-antibodies that have a desired effect on cells. The TSRI scientists used the technique to discover two antibodies that protect human cells from a cold virus.

20 Jan 2014

Vitamin D deficiency may lead to stiffening of blood vessels

UV-B radiation in sunlight is the most important factor for the production of vitamin D, and that is why many people suffer from low levels of vitamin D during the winter months.

20 Jan 2014

Breakthrough technology could provide new approach for treatment of chronic wounds

A team of researchers led by an NIBIB grantee at Vanderbilt University has created a biodegradable scaffold that enables sustained, local delivery of gene-silencing factors called siRNA to promote tissue regeneration. The team recently used the scaffold to successfully deliver siRNA to mice in order to locally silence a gene normally responsible for inhibiting blood vessel formation.

20 Jan 2014

Poisonous bacteria may one day become useful tool for industry and environmental protection

Buried deep in the mud along the banks of a remote salt lake near Yosemite National Park are colonies of bacteria with an unusual property: they breathe a toxic metal to survive.

20 Jan 2014

Enzyme News and Research

USF Health receives $2.1M grant to study on new factors required for growth of malaria-related parasites

Scientists identify critical regulator of molecule involved in progression of Alzheimer’s disease

New easy-to-use risk calculator helps predict heart failure patients' chances of survival

Scientists develop new genetic platform that yields novel antibiotic from ocean bacteria

Chinese and American researchers introduce new approach to gene therapy

New oral drug appears to offer hope for fighting indolent non-Hodgkin lymphoma

Scientists identify specific enzyme essential for brain development

Scientists showcase HDL nanotherapy that may provide solution to repeat heart attacks

Childhood brain cancer (ETMR/ETANTR): an interview with Dr. Nada Jabado, Department of Pediatrics at McGill University

Forest Laboratories third quarter net sales increase 24.9% to $846.8 million

European Commission approves ViiV Healthcare's Tivicay for treatment of HIV infected adults

Researchers find new candidate that may help combat malaria

Researchers identify molecular mechanism by which cocaine alters brain's reward circuits, causes addiction

Gene therapy edges closer for Parkinson’s disease

New technology may provide solution to high risk of repeat heart attacks, say scientists

Scientists uncover how microbiota metabolise complex dietary carbohydrates found in fruits, vegetables

TSRI scientists use new technique to discover two antibodies that protect human cells from cold virus

Vitamin D deficiency may lead to stiffening of blood vessels

Breakthrough technology could provide new approach for treatment of chronic wounds

Poisonous bacteria may one day become useful tool for industry and environmental protection

Biochemistry eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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