Eosinophil News and Research

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Eosinophils are a specialized type of cell within the immune system that are involved in anti-parasitic and inflammatory responses.

Immunological interactions between asthma, obesity, and the microbiota

This study summarizes the mechanisms associated with obesity-aggravated asthma.

18 Jan 2023

Dietary inulin fiber can promote allergy-related type of inflammation in the gut and lungs

A type of dietary fiber called inulin, commonly used in health supplements and known to have certain anti-inflammatory properties, can also promote an allergy-related type of inflammation in the lung and gut, and other parts of the body, according to a preclinical study from researchers in the Friedman Center for Nutrition and Inflammation and Jill Roberts Institute for Inflammatory Bowel Disease at Weill Cornell Medicine and in the Boyce Thompson Institute on Cornell's Ithaca campus.

2 Nov 2022

Progress and challenges in the development of mRNA vaccines against respiratory syncytial virus

New research discussed the structure and life cycle of respiratory syncytial virus (RSV), the current research on the treatment and prevention of RSV infections, and the advancements in RSV mRNA vaccine technology after the surge in vaccine research during the COVID-19 pandemic.

1 Nov 2022

Chinese study determines the real-world effectiveness of COVID-19 vaccines

A recent study aimed to determine the real-world effectiveness of COVID-19 vaccines against SARS-CoV-2 infection.

14 Oct 2022

Monoclonal antibody decreases asthma attacks by 27% in children and adolescents of color

A monoclonal antibody, mepolizumab, decreased asthma attacks by 27% in Black and Hispanic children and adolescents who have a form of severe asthma, are prone to asthma attacks and live in low-income urban neighborhoods, a National Institutes of Health clinical trial has found.

10 Aug 2022

Scientists discover a gene defect that results in allergic and autoimmune disease

Inflammation of the skin and the esophagus, food allergy and asthma are just some of the symptoms of a now 12-year-old boy who was the first to have a mutation on the IL-33 gene. An international team led by a physician from the Karl Landsteiner University for Health Sciences, Krems, discovered this new disease entity.

26 May 2022

Safety and immunogenicity of three-dose vaccination with the Pfizer/BioNtech SARS-CoV-2 mRNA vaccine

A recent article published in the Med journal reported that the SARS-CoV-2 booster vaccinations enhance the SARS-CoV-2 Omicron sublineage neutralizations.

29 Apr 2022

Interleukin-3 may contribute to alleviating asthma, research suggests

The messenger substance interleukin-3 produced by the body was previously considered to be pro-inflammatory in bronchial asthma.

21 Apr 2022

Genetic analysis reveals eosinophilic colitis as a unique disease

A condition called eosinophilic colitis is distinct from other, similar eosinophilic gastrointestinal diseases and inflammatory bowel disease, according to a genetic analysis published in Gastroenterology.

24 Feb 2022

Researchers investigate SARS-CoV-2 specific inflammatory response

New research can confirm that while some of the response from monocytes to SARS-CoV-2 is generic to virus infection, most of it SARS-CoV-2 specific, especially proinflammatory responses.

7 Jan 2022

Biologic agent dupilumab effective in improving asthma exacerbations and lung function, study shows

A new medication has been added to the treatment options for children with moderate-to-severe asthma. In a late-stage clinical trial, the biologic agent dupilumab reduced the rate of severe asthma attacks and improved lung function and asthma control for children ages 6 to 11.

9 Dec 2021

Early-stage interaction of monocytes with SARS-CoV-2-infected epithelial cell decides COVID-19 severity

A team of scientists from the USA and France has recently unveiled the mechanism of immune dysregulation in coronavirus disease 2019 (COVID-19) patients by analyzing the early-stage interaction between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected epithelial cells and immune cells. The study is currently available on the bioRxiv* preprint server.

30 Sep 2021

Childhood asthma is not a risk factor for COVID-19

A new study provides new insights on the association of childhood asthma and COVID-19.

26 Sep 2021

Dupilumab considerably reduced asthma exacerbations in young children, shows VOYAGE trial

Results from the VOYAGE study of dupilumab (Dupixent) showed that the monoclonal antibody significantly reduced exacerbations in children ages 6-11 with uncontrolled moderate-to-severe asthma, compared to placebo, according to research presented at the ATS 2021 International Conference. VOYAGE (NCT02948959) is a recently completed randomized, placebo-controlled double-blind multicenter phase 3 clinical trial, that took place in a number of countries.

20 May 2021

Phase 3 trial: New biologic therapy improves outcomes in adults, adolescents with severe asthma

Results from the NAVIGATOR study of tezepelumab showed that the new biologic therapy significantly reduced exacerbations requiring hospital stays and emergency department (ED) visits for adults and adolescents with severe, uncontrolled asthma, according to research presented at the ATS 2021 International Conference.

20 May 2021

Eosinophils modify the respiratory barrier during influenza A infection, shows study

For the first time in published literature, Le Bonheur Children's Hospital and University of Tennessee Health Science Center (UTHSC) researchers showed that a variety of white blood cells known as eosinophils modify the respiratory barrier during influenza A (IAV) infection, according to a recent paper in the journal Cells.

28 Apr 2021

Eosinophil News and Research

Further Reading

Immunological interactions between asthma, obesity, and the microbiota

Dietary inulin fiber can promote allergy-related type of inflammation in the gut and lungs

Progress and challenges in the development of mRNA vaccines against respiratory syncytial virus

Chinese study determines the real-world effectiveness of COVID-19 vaccines

Monoclonal antibody decreases asthma attacks by 27% in children and adolescents of color

Scientists discover a gene defect that results in allergic and autoimmune disease

Safety and immunogenicity of three-dose vaccination with the Pfizer/BioNtech SARS-CoV-2 mRNA vaccine

Interleukin-3 may contribute to alleviating asthma, research suggests

Genetic analysis reveals eosinophilic colitis as a unique disease

Researchers investigate SARS-CoV-2 specific inflammatory response

Biologic agent dupilumab effective in improving asthma exacerbations and lung function, study shows

Early-stage interaction of monocytes with SARS-CoV-2-infected epithelial cell decides COVID-19 severity

Childhood asthma is not a risk factor for COVID-19

Dupilumab considerably reduced asthma exacerbations in young children, shows VOYAGE trial

Phase 3 trial: New biologic therapy improves outcomes in adults, adolescents with severe asthma

Eosinophils modify the respiratory barrier during influenza A infection, shows study

Intestinal worm infection can cause severe sexually transmitted viral diseases

Intestinal worm infections can make African women more vulnerable to sexually-transmitted viral infections

Granulocyte changes could help predict patient outcomes in COVID-19

Researchers use urine test to identify and verify a patient's type of asthma

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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