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Resverlogix announces formation of international Clinical Steering Committee for RVX-208 "apabetalone" Phase 3 trial

Resverlogix announces formation of international Clinical Steering Committee for RVX-208 "apabetalone" Phase 3 trial

Resverlogix Corp. is pleased to announce the formation of an international Clinical Steering Committee for the RVX-208 "apabetalone" Phase 3 clinical trial BETonMACE assessing major adverse cardiac events (MACE) in high-risk vascular patients with diabetes mellitus and a recent Acute Coronary Syndrome event. BETonMACE is expected to start in the fall of 2015. [More]
NYUCD awarded $1.7M Health Resources and Service Administration training grant

NYUCD awarded $1.7M Health Resources and Service Administration training grant

New York University College of Dentistry has been awarded a five-year, $1.7M Health Resources and Service Administration training grant entitled, "Preparing the Future Dental Workforce for Underserved Young Child and Adolescent Populations ("Preparing the Future"). [More]
Benefits and risks of taking antidepressant medications during pregnancy

Benefits and risks of taking antidepressant medications during pregnancy

Treating maternal psychiatric disorder with commonly used antidepressants is associated with a lower risk of certain pregnancy complications including preterm birth and delivery by Caesarean section, according to researchers at Columbia University's Mailman School of Public Health, Columbia University Medical Center, and the New York State Psychiatric Institute. However, the medications -- selective serotonin reuptake inhibitors, or SSRIs -- resulted in an increased risk of neonatal problems. [More]
Weight cycling not associated with overall risk of cancer

Weight cycling not associated with overall risk of cancer

The first comprehensive study of its kind finds weight cycling, repeated cycles of intentional weight loss followed by regain, was not associated with overall risk of cancer in men or women. The study by American Cancer Society investigators is the largest to date to investigate weight cycling with cancer risk. [More]
Anti-dementia drugs could result in harmful weight loss, say researchers

Anti-dementia drugs could result in harmful weight loss, say researchers

Medications commonly used to treat dementia could result in harmful weight loss, according to UC San Francisco researchers, and clinicians need to account for this risk when prescribing these drugs to older adults, they said. [More]
PHI model helps identify top health risks associated with chronic diseases

PHI model helps identify top health risks associated with chronic diseases

Public health agencies across the globe are challenged with preventing the spread of chronic diseases while dealing with limited funds and devastating budget cuts. [More]
Study evaluates costs and benefits of medical board recertification for improving healthcare quality

Study evaluates costs and benefits of medical board recertification for improving healthcare quality

Many physicians are pushing back against or debating new requirements for maintaining medical board certifications, which affect more than 250,000 physicians nationwide. Now, a new study by UC San Francisco and Stanford University researchers concludes that the cost of implementing the most recent requirements will be an estimated $5.7 billion over the next 10 years. [More]
Patients with HPV traces post-treatment more likely to have oropharyngeal cancer recurrence

Patients with HPV traces post-treatment more likely to have oropharyngeal cancer recurrence

Oropharyngeal cancer patients who were found to have detectable traces of human papillomavirus type 16 (HPV16) in their saliva following cancer treatment are at an increased risk for recurrence, a study led by researchers at the Johns Hopkins Bloomberg School of Public Health has found. [More]
amfAR releases recommendations to help U.S. states to achieve goals of National HIV/AIDS Strategy

amfAR releases recommendations to help U.S. states to achieve goals of National HIV/AIDS Strategy

Major achievements have been made in the domestic HIV/AIDS response as a result of increased realignment and coordination of efforts at the federal level. However, that level of consistent coordination and alignment has yet to take place in most states. In an effort to identify what needs to be done, amfAR, The Foundation for AIDS Research, in collaboration with the National HIV/AIDS Initiative at the O'Neill Institute for National and Global Health Law at Georgetown Law, has released a set of recommendations for how states across the U.S. can improve HIV prevention and care outcomes in an effort to achieve the goals identified within the National HIV/AIDS Strategy. [More]
Astellas reports topline results from isavuconazole Phase 3 study in candidemia and other invasive Candida infections

Astellas reports topline results from isavuconazole Phase 3 study in candidemia and other invasive Candida infections

Astellas today announced topline results from the Phase 3 ACTIVE study evaluating the efficacy and safety of intravenous (IV) and oral isavuconazole, commercially known as CRESEMBA (isavuconazonium sulfate), under development for adults with candidemia and other invasive Candida infections. [More]

New set of clinical practice guidelines released to address temperature management during open heart surgery

The Society of Thoracic Surgeons, the Society of Cardiovascular Anesthesiologists, and the American Society of ExtraCorporeal Technology have released a set of clinical practice guidelines to address management of a patient's temperature during open heart surgery. The guidelines appear in the August issue of The Annals of Thoracic Surgery and were published simultaneously in two other journals. [More]
Researchers explore impact of nutrients, probiotics before and during pregnancy on mothers and babies

Researchers explore impact of nutrients, probiotics before and during pregnancy on mothers and babies

Researchers in the United Kingdom (Southampton), Singapore and New Zealand (Auckland) from the EpiGen Global Research Consortium are to trial the use of a combination of nutrients and probiotics before and during pregnancy in a bid to improve the health of mothers and their babies. [More]
Legal regulations on alcohol consumption have preventive effect on young consumers

Legal regulations on alcohol consumption have preventive effect on young consumers

Young men are at risk from alcohol consumption. Regulations such as the minimum legal drinking age can protect them. As a national study headed by UZH scientists reveals: The more legal measures for alcohol prevention are enforced in a canton, the less young men drink excessively. However, this is not effective for high-risk consumers such as young men with a tendency towards sensation seeking or antisocial behavior. [More]
Moffitt researchers find cancer healthcare disparities in LGBTQ community

Moffitt researchers find cancer healthcare disparities in LGBTQ community

The Lesbian, Gay, Bisexual, Transgender/Transsexual, Queer/Questioning (LGBTQ) community is a growing and medically-underserved minority population in the United States, with 3 to 12 percent of the population estimated to identify as LGBTQ. [More]
Study elucidates on global prevalence of chronic hepatitis B infections

Study elucidates on global prevalence of chronic hepatitis B infections

Hepatitis B infections are among the most common infectious diseases worldwide. The disease can become chronic, and is one of the most important causes of severe diseases such as liver cancer. In the scope of an international study funded by the World Health Organization, scientists from the Helmholtz Centre for Infection Research in Braunschweig determined how often the chronic infection occurs in different countries and how many people of the general population are affected. They noted strong differences between different countries. [More]
Research brief provides clinical validation of LOXO-101 Phase 1 trial for treatment of TRK fusion cancer

Research brief provides clinical validation of LOXO-101 Phase 1 trial for treatment of TRK fusion cancer

The University of Colorado Cancer Center and Loxo Oncology, Inc., a biopharmaceutical company focused on the discovery, development and commercialization of targeted cancer therapies, today announced the publication of a research brief in the online edition of the journal Cancer Discovery, describing the first patient with a tropomyosin receptor kinase fusion cancer enrolled in the Phase 1 dose escalation trial of LOXO-101, the only selective TRK inhibitor in clinical development. [More]
Europe has increasing prevalence of fungal resistance, warns ESCMID

Europe has increasing prevalence of fungal resistance, warns ESCMID

The European Society of Clinical Microbiology and Infectious Disease – an organization that explores the risks and best practices in infectious disease – is imploring global healthcare professionals and bodies to take a more active role in the growing problem of fungal resistance. [More]
Research brief describes enrollment of first patient with TRK fusion cancer in LOXO-101 Phase 1 trial

Research brief describes enrollment of first patient with TRK fusion cancer in LOXO-101 Phase 1 trial

The University of Colorado Cancer Center and Loxo Oncology, Inc., a biopharmaceutical company focused on the discovery, development and commercialization of targeted cancer therapies, today announced the publication of a research brief in the online edition of the journal Cancer Discovery, describing the first patient with a tropomyosin receptor kinase (TRK) fusion cancer enrolled in the Phase 1 dose escalation trial of LOXO-101, the only selective TRK inhibitor in clinical development. [More]
New special issue addresses hottest areas of research in cancer and metabolism

New special issue addresses hottest areas of research in cancer and metabolism

The latest Special Issue in ecancermedicalscience collects four original articles from experts in cancer and metabolism, addressing the hottest areas of research in this rapidly developing field. [More]
Prostate cancer patients more likely to receive medical care matched to level of risk

Prostate cancer patients more likely to receive medical care matched to level of risk

After decades of overtreatment for low-risk prostate cancer and inadequate management of its more aggressive forms, patients are now more likely to receive medical care matched to level of risk, according to a study by researchers at UC San Francisco. [More]
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