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Janssen, Bayer HealthCare announce results from landmark studies evaluating safety profile of XARELTO in NVAF patients

Janssen, Bayer HealthCare announce results from landmark studies evaluating safety profile of XARELTO in NVAF patients

Janssen Pharmaceuticals, Inc., and its development partner, Bayer HealthCare, today announced results from PMSS (Post-Marketing Safety Surveillance) and XANTUS (XARELTO for Prevention of Stroke in Patients with Atrial Fibrillation), their landmark real-world studies evaluating the safety of XARELTO in people with non-valvular atrial fibrillation (NVAF). [More]
Medical case report of woman with Channelopathy-associated Insensitivity to Pain Syndrome

Medical case report of woman with Channelopathy-associated Insensitivity to Pain Syndrome

The report, published on F1000Research and titled Neuropathic pain in a patient with congenital insensitivity to pain has just passed peer review. It concerns a unique case of a woman with Channelopathy-associated Insensitivity to Pain (CIP) Syndrome, who developed features of neuropathic pain after sustaining pelvic fractures and an epidural hematoma that impinged on the right fifth lumbar (L5) nerve root. These injuries were sustained during a painless labour, which culminated in a Caesarean section. [More]
New non-invasive spinal cord stimulation helps paralyzed men voluntarily move their legs

New non-invasive spinal cord stimulation helps paralyzed men voluntarily move their legs

Five men with complete motor paralysis were able to voluntarily generate step-like movements thanks to a new strategy that non-invasively delivers electrical stimulation to their spinal cords, according to a new study funded in part by the National Institutes of Health. The strategy, called transcutaneous stimulation, delivers electrical current to the spinal cord by way of electrodes strategically placed on the skin of the lower back. [More]
Scientists propose new spinal cord stimulation strategy to activate motor neurons

Scientists propose new spinal cord stimulation strategy to activate motor neurons

Patients, doctors and researchers look with great expectations to epidural electrostimulation, a medical technique that could alleviate the condition of subjects affected by paralysis due to spinal cord injury. Although still relatively rudimentary, the technique is constantly being improved thanks to research. [More]
Mild head injury patients having lower serum S100B levels unlikely to have intracranial hemorrhage

Mild head injury patients having lower serum S100B levels unlikely to have intracranial hemorrhage

Researchers conducted a prospective observational study in elderly patients and adult patients receiving antiplatelet therapy who presented with mild head injury at two trauma hospitals in Vienna: the Trauma Hospital Meidling and the Donauspital. [More]
Simple steps help accelerate recovery, reduce cost of care in people undergoing colorectal surgery

Simple steps help accelerate recovery, reduce cost of care in people undergoing colorectal surgery

Simple steps that include the consistent use of experienced medical teams for a single type of surgery, preemptive antibiotics before the procedure, less reliance on potent opioids during recovery and urging patients to get out of bed and move around sooner can not only prevent infections, blood clots and other serious complications in people undergoing colorectal operations, but can also accelerate recovery and reduce cost of care, according to results of an ongoing program at The Johns Hopkins Hospital. [More]
Neurosurgeon performs first endoscopic removal of spinal tumor at Rhode Island Hospital

Neurosurgeon performs first endoscopic removal of spinal tumor at Rhode Island Hospital

The spinal tumor grew back. Even though the 16-year old patient endured surgery a year earlier to remove and diagnose the lesion, it was back and its cause unknown. Determined to identify the tumor tissue and set the patient on an appropriate treatment regimen, Albert Telfeian, M.D., a neurosurgeon at Rhode Island Hospital and Hasbro Children's Hospital, performed the first reported case of extracting the tumor endoscopically while the patient was awake and under a local anesthetic. [More]
Janssen, Bayer HealthCare initiate CALLISTO program to study rivaroxaban in patients with active cancer

Janssen, Bayer HealthCare initiate CALLISTO program to study rivaroxaban in patients with active cancer

Janssen Pharmaceuticals, Inc. and its development partner, Bayer HealthCare, today announced the initiation of CALLISTO, a new comprehensive clinical research program for their novel oral anticoagulant, rivaroxaban, in patients with active cancer. The studies are evaluating the medicine for the prevention and treatment of life-threatening blood clots in patients with a wide range of cancer types. [More]
Short course of oral steroids unlikely to provide much benefit for patients with acute sciatica

Short course of oral steroids unlikely to provide much benefit for patients with acute sciatica

Among patients with acute sciatica caused by a herniated lumbar disk (a condition also known as "acute radiculopathy"), a short course of oral steroids resulted in only modest improvement in function and no significant improvement in pain, according to a study published today in the Journal of the American Medical Association. [More]
IV cosyntropin therapy matches EBP in relieving pain from post-dural puncture headache

IV cosyntropin therapy matches EBP in relieving pain from post-dural puncture headache

Intravenous (IV) cosyntropin therapy was equivalent to epidural blood patch (EBP) in relieving pain from post-dural puncture headache (PDPH) with potential for fewer complications and lower costs, data from a randomized, controlled trial showed. [More]

Wings for Life World Run to fund breakthrough clinical study on spinal cord injury

It all started with a single toe. Even today, Dr. Susan Harkema recalls the words spoken by one of the research participants: "Look Susie, I can move my toe." The patient's name was Rob Summers and he was completely paralyzed from the neck down. After a car accident he was told he would never be able to walk again. [More]
Experts provide suggestions to prevent neurological injuries associated with epidural steroid injections

Experts provide suggestions to prevent neurological injuries associated with epidural steroid injections

Epidural steroid injections are commonly used to treat pain; however, they can in rare situations produce life-threatening neurological injuries such as stroke and paralysis. In the Online First edition of February's Anesthesiology, the official medical journal of the American Society of Anesthesiologists, a panel of experts representing 13 national medical organizations provided 17 suggestions aimed at preventing such injuries and improving patient safety. [More]
Peanut-shaped exercise ball promotes positive labor outcomes, reduces duration of delivery process

Peanut-shaped exercise ball promotes positive labor outcomes, reduces duration of delivery process

According to a new study by nurse researchers at Banner Good Samaritan Medical Center, a Phoenix hospital part of Banner Health, a peanut-shaped exercise ball can be a highly effective tool to accelerate the labor process for women with an epidural. The research shows women utilizing the peanut ball were half as likely to undergo a cesarean surgery and delivered babies faster than those who did not use the ball. [More]
Daiichi Sankyo receives FDA approval for SAVAYSA (edoxaban) Tablets

Daiichi Sankyo receives FDA approval for SAVAYSA (edoxaban) Tablets

Daiichi Sankyo Company, Limited (hereafter, Daiichi Sankyo) today announced that the U.S. Food and Drug Administration has approved SAVAYSA (edoxaban) Tablets, an oral, once-daily selective factor Xa-inhibitor, to reduce the risk of stroke and systemic embolism (SE) in patients with non-valvular atrial fibrillation (NVAF). [More]
National Spine & Pain Centers opens new pain management center in Cumberland, Maryland

National Spine & Pain Centers opens new pain management center in Cumberland, Maryland

Over 100 million adults suffer from chronic pain and about half of those suffer from this pain daily. Chronic and acute pain dramatically impacts quality of life. The specialty of pain management is born to fulfill the need for non-surgical, interventional solutions and medication management to treat all types of pain. [More]
Electrical stimulation technology can help SCI patients regain bladder control

Electrical stimulation technology can help SCI patients regain bladder control

When individuals suffer a spinal cord injury, paralysis is only a part of the major impact on quality of life. Often they also lose bladder control, which frequently causes infections that can lead to kidney damage. [More]
Epidural and spinal anesthesia safe for relieving pain during childbirth

Epidural and spinal anesthesia safe for relieving pain during childbirth

Women seeking pain relief during childbirth should be comforted to know that epidural and spinal anesthesia are extremely safe, suggests a study of more than 80,000 women that reviewed anesthesia complications during obstetrical care. [More]
Pregnant women with low vitamin D levels experience more pain during labor

Pregnant women with low vitamin D levels experience more pain during labor

Pregnant women with low vitamin D levels experience an increased amount of pain during labor, according to a study presented at the ANESTHESIOLOGY 2014 annual meeting. Vitamin D deficiency has long been associated with depression and pain, but this is the first study to demonstrate its association with increased consumption of pain medication during childbirth. [More]

Researchers compare effects of early and late epidurals given during labour

When a woman is in labour, the appropriate time to give an epidural during childbirth is when she asks for it, a new study suggests. [More]
Epidurals and reduced postpartum depression: an interview with Dr. Zakowski

Epidurals and reduced postpartum depression: an interview with Dr. Zakowski

The “maternity blues”, which resolve within 10 days of giving birth, occurs in up to 80% of new moms. A major depressive episode, by Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria, is defined as having at least a 2-week period of persistent depressed mood ... [More]
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