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Study: Male mice fed with high-fat diet are more likely to father offspring with higher levels of body fat

Study: Male mice fed with high-fat diet are more likely to father offspring with higher levels of body fat

Male mice who were fed a high-fat diet and became obese were more likely to father offspring who also had higher levels of body fat, a new Ohio University study finds. [More]
GSA selects five early career researchers as recipients of fall 2013 DeLill Nasser Award

GSA selects five early career researchers as recipients of fall 2013 DeLill Nasser Award

The Genetics Society of America is pleased to announce the selection of five early career researchers - one graduate student and four postdoctoral researchers - as recipients of a fall 2013 DeLill Nasser Award for Professional Development in Genetics. [More]
Prostate cancer and DNA: an interview with Dr. Jianfeng Xu, Wake Forest School of Medicine

Prostate cancer and DNA: an interview with Dr. Jianfeng Xu, Wake Forest School of Medicine

Prostate cancer development is associated with both inherited and acquired genetic alterations. More than 70 inherited genetic variants have been consistently identified in human DNA that may contribute to susceptibility or risk of prostate cancer. [More]
Obesity in pregnancy can program kids to develop metabolic problems

Obesity in pregnancy can program kids to develop metabolic problems

Scientists in Sydney, Australia, have discovered that obesity and type 2 diabetes in pregnancy can program children to develop metabolic problems later in life. The good news is, this legacy is not set in stone-if children of obese mothers are careful about what they eat, it can be overturned. [More]
Scientists identify new markers for obesity treatment

Scientists identify new markers for obesity treatment

Would you be more likely to try a diet and exercise regimen if you knew in advance if it would actually help you lose weight? Thanks to a new report published in the June 2013 issue of The FASEB Journal, this could become a reality. [More]

Chromatrap® ChIP assay kit enriches epigenetic marks from primary human tissue cells

A new application note from Porvair Sciences details a protocol for its Chromatrap® ChIP assay kit that has been developed to enrich epigenetic marks from primary human tissue cells. [More]
Researchers examine how BRD4 contributes to sustained presence of NF-kappa B in cancer cells

Researchers examine how BRD4 contributes to sustained presence of NF-kappa B in cancer cells

In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth. [More]
Modifications in key epigenetic markers influence human embryonic stem cells

Modifications in key epigenetic markers influence human embryonic stem cells

Scientists have long known that control mechanisms known collectively as "epigenetics" play a critical role in human development, but they did not know precisely how alterations in this extra layer of biochemical instructions in DNA contribute to development. [More]

New mechanism that plays important role in meiosis identified

The Research Group headed by molecular biologist Andrea Pichler from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg has made an important discovery in meiosis research. [More]
Researchers describe alterations in long noncoding RNA sequences in Rett syndrome

Researchers describe alterations in long noncoding RNA sequences in Rett syndrome

Researchers at the Epigenetics and Cancer Biology Program at IDIBELL led by Manel Esteller, ICREA researcher and professor of genetics at the University of Barcelona, have described alterations in noncoding long chain RNA sequences in Rett syndrome. [More]
Hospital for Special Surgery receives grant for new genomics center to study autoimmune diseases

Hospital for Special Surgery receives grant for new genomics center to study autoimmune diseases

Hospital for Special Surgery in New York City has received a $5.6 million grant from The Tow Foundation to establish the Hospital for Special Surgery Genomics Center. [More]

Individual hydroxymethylcytosine molecules in DNA detected by new method involving chemical modification and nanopore analysis

Changes in the bases that make up DNA act as markers, telling a cell which genes it should read and which it shouldn’t. In the journal Angewandte Chemie, a British team has now introduced a new method that makes it possible to enrich the rare gene segments that contain the modified base hydroxymethylcytosine and to identify individual hydroxymethylcytosine molecules in DNA. Such modifications are associated with autoimmune diseases and cancer. [More]
Aurigene and Endo’s collaborative efforts yield novel drug candidates

Aurigene and Endo’s collaborative efforts yield novel drug candidates

Aurigene and Endo entered into collaboration in 2009, for multiple integrated drug discovery programs in the areas of Inflammation and Oncology. [More]
Animal medication studies may lead way in discovering new drugs to relieve human suffering

Animal medication studies may lead way in discovering new drugs to relieve human suffering

It's been known for decades that animals such as chimpanzees seek out medicinal herbs to treat their diseases. But in recent years, the list of animal pharmacists has grown much longer, and it now appears that the practice of animal self-medication is a lot more widespread than previously thought, according to a University of Michigan ecologist and his colleagues. [More]
Immunotherapy and epigenetics advancements presented by Ludwig at the American Association for Cancer Research

Immunotherapy and epigenetics advancements presented by Ludwig at the American Association for Cancer Research

A dozen Ludwig scientists from around the world presented the latest advancements in basic and clinical cancer research at this week’s American Association for Cancer Research (AACR) Annual Meeting 2013. Progress in immunotherapy and epigenetics led the program with important diagnostic and treatment implications for emerging cancer therapy. [More]
Cuts to NIH 'inconsistent' with university interest in global health research

Cuts to NIH 'inconsistent' with university interest in global health research

"As the debate over federal budget allocations and cuts continues, the National Institutes of Health, a leading funder for both domestic and global health research, could experience a whopping $1 billion budget cut," Karen Siegel and colleagues from Emory University write in the Health Affairs Blog. [More]
Weill Cornell Medical College sets up new Feil Family Brain and Mind Research Institute

Weill Cornell Medical College sets up new Feil Family Brain and Mind Research Institute

Weill Cornell Medical College has established the new Feil Family Brain and Mind Research Institute, a unique, multidisciplinary translational neuroscience research hub. Named in honor of long-time benefactors Gertrude and Louis Feil, the institute was created with a generous $28 million gift from the Feil Family. [More]
Scientists discover that drinking milk early in life could change how certain genes are expressed

Scientists discover that drinking milk early in life could change how certain genes are expressed

It seems the ads were right. A milk mustache is a good thing to have. Animal and dairy scientists have discovered that drinking milk at an early age can help mammals throughout their lives. [More]
Discovery of new signalling pathway creates hope for hormone therapy resistance

Discovery of new signalling pathway creates hope for hormone therapy resistance

A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive breast cancer cells that are resistant to hormone therapies such as tamoxifen, aromatase inhibitors or fulvestrant. [More]
Study links mutated histone protein to rare brain stem cancer in children

Study links mutated histone protein to rare brain stem cancer in children

Most cancer treatments are blunt. In an attempt to eradicate tumors, oncologists often turn to radiation or chemotherapy, which can damage healthy tissue along with the cancerous growths. [More]