Epigenetics News and Research RSS Feed - Epigenetics News and Research

New chromatin immunoprecipitation sequencing kit developed by Porvair Sciences

New chromatin immunoprecipitation sequencing kit developed by Porvair Sciences

Porvair Sciences has developed a new ChIP sequencing assay kit extending the benefits of their proprietary Chromatrap® solid state ChIP technology to preparation of purified Chromatin for the generation of sequencing libraries. [More]
Researchers develop new single-cell technique to study environmental effects on DNA

Researchers develop new single-cell technique to study environmental effects on DNA

Researchers at the BBSRC-funded Babraham Institute, in collaboration with the Wellcome Trust Sanger Institute Single Cell Genomics Centre, have developed a powerful new single-cell technique to help investigate how the environment affects our development and the traits we inherit from our parents. [More]
Video interview highlights latest research developments in women’s reproductive health using Chromatrap solid state ChIP assay

Video interview highlights latest research developments in women’s reproductive health using Chromatrap solid state ChIP assay

An informative video interview with Professor Steve Conlan of the College of Medicine at Swansea University (UK) highlights the latest research developments in women’s reproductive health using unique molecular biology tools. [More]
Biologists develop new method to investigate cell surface's organization on nanometer scale

Biologists develop new method to investigate cell surface's organization on nanometer scale

After a ten-year effort, Prof. Dr. Michael Reth from the Institute of Biology III of the University of Freiburg and the Max Planck Institute of Immunobiology and Epigenetics has developed a method to investigate the cell surface's organization on a nanometer scale. [More]
Alcoholic liver disease: an interview with Dr Vinood Patel, University of Westminster

Alcoholic liver disease: an interview with Dr Vinood Patel, University of Westminster

Alcoholic liver disease (ALD) is one of the leading causes of death worldwide and also in the UK. As its name indicates this disease arises due to consuming excessive amounts of alcohol (80 g/day) over an extended period, normally 10-20 years. [More]
Scientists discover major breakthrough in cancer treatment

Scientists discover major breakthrough in cancer treatment

Scientists at the Sahlgrenska Academy, University of Gothenburg, have developed a new cancer treatment that has proved to be effective in mice. The treatment, which is presented in the prestigious scientific journal PNAS, is based on newly discovered properties of the so-called BET bromodomain inhibitors. [More]
Combination of effective drugs for Parkinson's disease controls symptoms of Rett syndrome in mice

Combination of effective drugs for Parkinson's disease controls symptoms of Rett syndrome in mice

IDIBELL researchers, led by the director of the Program for Epigenetics and Cancer Biology, ICREA researcher and Professor of Genetics at the University of Barcelona, Manel Esteller, have shown that a combination of effective drugs for Parkinson's disease in mice that are used as a model of human Rett syndrome reduces some of the symptoms associated with this disease. [More]
DNA methylation identified as potential anti-TNF response biomarker for RA

DNA methylation identified as potential anti-TNF response biomarker for RA

DNA methylation has been identified as a potential biomarker of response to etanercept and adalimumab in patients with rheumatoid arthritis (RA) according to preliminary results from one of the largest methylome-wide investigations of treatment response to anti-TNF therapies. [More]
Study examines effect of phthalate exposure in humans’ sperm epigenetics

Study examines effect of phthalate exposure in humans’ sperm epigenetics

A new three-year, $440,000 study led by environmental health scientist Richard Pilsner at the University of Massachusetts Amherst is now underway to investigate whether phthalate levels in expectant fathers have an effect on the couples' reproductive success, via epigenetic modifications of sperm DNA. [More]
Molecular mechanisms regulating tumour initiation in skin SCC uncovered

Molecular mechanisms regulating tumour initiation in skin SCC uncovered

Advanced online publication in Nature: Researchers at the Université libre de Bruxelles, ULB uncover the molecular mechanisms regulating tumour initiation and cancer stem cells functions in skin squamous cell carcinoma. [More]
Research finding paves way for targeted approaches to treating cancer patients

Research finding paves way for targeted approaches to treating cancer patients

Twelve years ago, UNC School of Medicine researcher Brian Strahl, PhD, found that a protein called Set2 plays a role in how yeast genes are expressed - specifically how DNA gets transcribed into messenger RNA. Now his lab has found that Set2 is also a major player in DNA repair, a complicated and crucial process that can lead to the development of cancer cells if the repair goes wrong. [More]
SGC and CHDI Foundation collaborate to discover new drug targets for Huntington's disease

SGC and CHDI Foundation collaborate to discover new drug targets for Huntington's disease

The Structural Genomics Consortium (SGC) and CHDI Foundation have entered into a unique open-access research collaboration to discover and characterize new drug targets for Huntington's disease (HD) using structural and chemical biology In this first partnership of its kind, SGC and CHDI have explicitly agreed not to file for patents on any of the collaborative research and to make all reagents and knowledge available without restriction to the wider research community, including pharmaceutical, biotech, and academic research groups. [More]
INTEGRA's VIAFLO 96 handheld multichannel pipette improves efficiency of genetic screening

INTEGRA's VIAFLO 96 handheld multichannel pipette improves efficiency of genetic screening

The Institute of Genetics and Development of Rennes, France reports on how, using a VIAFLO 96 handheld multichannel pipette from INTEGRA, they have been able to improve the efficiency and speed with which they replicate yeast strain collections and perform genetic screens in 96 well plates. [More]
Son's vulnerability for alcohol use disorders could be shaped by father

Son's vulnerability for alcohol use disorders could be shaped by father

Even before conception, a son's vulnerability for alcohol use disorders could be shaped by a father who chronically drinks to excess, according to a new animal study from the University of Pittsburgh School of Medicine. [More]
New data on Gilotrif and investigational compounds to be presented at 50th ASCO annual meeting

New data on Gilotrif and investigational compounds to be presented at 50th ASCO annual meeting

Boehringer Ingelheim today announced that new data will be presented from 7 abstracts for Gilotrif (afatinib) and investigational compounds, including nintedanib and BI 836845, from its oncology pipeline at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, IL, on May 30 – June 3, 2014. [More]
Agena Bioscience expands ultrasensitive somatic mutation detection technology

Agena Bioscience expands ultrasensitive somatic mutation detection technology

Agena Bioscience, Inc., which recently acquired the Bioscience business of Sequenom, Inc., today announced expansion of the UltraSEEK™ technology, the first ultrasensitive somatic mutation detection technology for high-throughput and definitive interrogation of rare mutations that occur at less than 1% abundance in matched tissue, circulating plasma, and tumor samples. [More]

Agena Bioscience acquires Sequenom’s Bioscience business

Agena Bioscience, Inc., a portfolio company of Telegraph Hill Partners (THP), today acquired the Bioscience business of Sequenom, Inc., which sells the MassARRAY® System for mass spectrometry-based detection of nucleic acids in research and clinical laboratories. [More]
New laser method provides a better understanding on how genes are controlled, regulated

New laser method provides a better understanding on how genes are controlled, regulated

Almost every one of our cells has an entire copy of our genome. But only differing subsets of genes are active and expressed in any given cell. [More]
Researchers examine how basic biology of aging drives chronic disease

Researchers examine how basic biology of aging drives chronic disease

A new collection of articles appearing in The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences examine how the basic biology of aging drives chronic disease. [More]
A potential epigenetic 'on-off' switch for cancer

A potential epigenetic 'on-off' switch for cancer

A team of Boston University School of Medicine (BUSM) researchers have proposed that an "on and off" epigenetic switch could be a common mechanism behind the development of different types of cancer. Epigenetics is the phenomena whereby genetically identical cells express their genes differently, resulting in different physical traits. [More]