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GARFIELD-AF Registry: All-cause death is most frequent major event in newly diagnosed AF patients

GARFIELD-AF Registry: All-cause death is most frequent major event in newly diagnosed AF patients

The first-ever two-year outcomes from the Global Anticoagulant Registry in the Field - Atrial Fibrillation (GARFIELD-AF) showcased at ESC Congress 2015 expose that all-cause death was the most frequent major event in more than 17,000 newly diagnosed AF patients, far exceeding the rate of stroke or major bleeding. [More]
New treatment algorithm for pulmonary arterial hypertension launched in 2015 ESC/ERS Guidelines

New treatment algorithm for pulmonary arterial hypertension launched in 2015 ESC/ERS Guidelines

A novel treatment algorithm for pulmonary arterial hypertension is launched today in new pulmonary hypertension guidelines from the European Society of Cardiology and European Respiratory Society. [More]
Children's Hospital Los Angeles successfully implants Melody Transcatheter Pulmonary Valve in child actor

Children's Hospital Los Angeles successfully implants Melody Transcatheter Pulmonary Valve in child actor

Cardiologists from Children's Hospital Los Angeles successfully implanted a Melody Transcatheter Pulmonary Valve in child actor Max Page, the boy who made headlines playing mini Darth Vader in a 2011 Super Bowl ad for Volkswagen. [More]
Theresa Alenghat receives 2015 AGA-CCFA-Janssen Research Award in IBD Epigenetics Research

Theresa Alenghat receives 2015 AGA-CCFA-Janssen Research Award in IBD Epigenetics Research

The American Gastroenterological Association, in partnership with the Crohn's & Colitis Foundation of America and Janssen Biotech, Inc., announced today that Theresa Alenghat, VMD, PhD, from Cincinnati Children's Hospital Medical Center, OH, was awarded with the 2015 AGA-CCFA-Janssen Research Award in Inflammatory Bowel Disease (IBD) Epigenetics Research. [More]
Breakthrough antibody therapy shows significant promise against drug-resistant multiple myeloma

Breakthrough antibody therapy shows significant promise against drug-resistant multiple myeloma

In its first clinical trial, a breakthrough antibody therapy produced at least partial remissions in a third of patients with multiple myeloma who had exhausted multiple prior treatments, investigators at Dana-Farber Cancer Institute and other organizations report today online in the New England Journal of Medicine. [More]
Inpatient palliative care visits associated with improved quality of life for patients with heart failure

Inpatient palliative care visits associated with improved quality of life for patients with heart failure

A recent randomized trial conducted by researchers at Abbott Northwestern Hospital, part of Allina Health, found that inpatient palliative care (PC) visits were associated with improved quality of life and symptom burden for patients with heart failure (HF). [More]
FDA, EMA accept filing applications for Boehringer Ingelheim's afatinib to treat patients with advanced SCC of the lung

FDA, EMA accept filing applications for Boehringer Ingelheim's afatinib to treat patients with advanced SCC of the lung

Boehringer Ingelheim today announced that both the U.S. Food and Drug Administration and the European Medicines Agency have accepted filing applications for afatinib for the treatment of patients with advanced squamous cell carcinoma (SCC) of the lung progressing after treatment with first-line chemotherapy. [More]
Clementia expands enrollment to include children with FOP in ongoing Phase 2 clinical trial

Clementia expands enrollment to include children with FOP in ongoing Phase 2 clinical trial

Clementia Pharmaceuticals, Inc. today announced the initiation of enrollment of children as young as 6 years old in the company's ongoing Phase 2 study of palovarotene for the treatment of fibrodysplasia ossificans progressiva (FOP). [More]
Cognitive factors associated with activity, participation in everyday life among people with MS

Cognitive factors associated with activity, participation in everyday life among people with MS

Kessler Foundation researchers found that processing speed is the primary limiting factor associated with activity and participation in everyday life among people with multiple sclerosis (MS). "Factors that moderate activity limitation and participation restriction in people with multiple sclerosis" was published in the American Journal of Occupational Therapy. [More]
Researchers find effectiveness of ramelteon for treatment of sleep disturbances after TBI

Researchers find effectiveness of ramelteon for treatment of sleep disturbances after TBI

Kessler researchers found preliminary evidence for the effectiveness of ramelteon for the treatment of sleep disturbances after traumatic brain injury (TBI). The article, "Archives of Physical Medicine and Rehabilitation on May 28, 2015. Authors are Anthony Lequerica, PhD, and Nancy Chiaravalloti, PhD, of Kessler Foundation, Neil Jasey, MD, of Kessler Institute for Rehabilitation, and Jaclyn Portelli Tremont, MA, of Robert Wood Johnson Medical School, Rutgers University. [More]
Valeant enters into definitive agreement to acquire Sprout Pharmaceuticals

Valeant enters into definitive agreement to acquire Sprout Pharmaceuticals

Valeant Pharmaceuticals International, Inc. and Sprout Pharmaceuticals, Inc. today announced that they have entered into a definitive agreement under which a wholly-owned subsidiary of Valeant will acquire Sprout, on a debt-free basis, for approximately $1 billion in cash, plus a share of future profits based upon the achievement of certain milestones. [More]
GARFIELD-AF data to demonstrate impact of antithrombotic treatment patterns on AF patients at ESC Congress 2015

GARFIELD-AF data to demonstrate impact of antithrombotic treatment patterns on AF patients at ESC Congress 2015

New analyses from the Global Anticoagulant Registry in the Field - Atrial Fibrillation (GARFIELD-AF) will be presented at ESC Congress 2015 to be held in London, United Kingdom, from August 29 to September 2, 2015. [More]
New supercomputer models can capture the behavior of human heart valves

New supercomputer models can capture the behavior of human heart valves

New supercomputer models have come closer than ever to capturing the behavior of normal human heart valves and their replacements, according to recent studies by groups including scientists at the Institute for Computational Engineering and Sciences at The University of Texas at Austin and the Department of Mechanical Engineering at Iowa State University. [More]
Only 1 in 10 heart failure patients referred to cardiac rehabilitation program after hospitalization

Only 1 in 10 heart failure patients referred to cardiac rehabilitation program after hospitalization

Only 1 in 10 heart failure patients is referred to a cardiac rehabilitation program after being hospitalized, despite strong evidence that such exercise programs improve quality of life and reduce the likelihood of future hospitalizations. [More]
Loyola implants new percutaneous aortic heart valve that does not require open surgery

Loyola implants new percutaneous aortic heart valve that does not require open surgery

Loyola University Medical Center is the first center in Illinois to implant a new percutaneous aortic heart valve that does not require open heart surgery. [More]
Physical activity linked to reduced paediatric MS burden

Physical activity linked to reduced paediatric MS burden

A cross-sectional study has found an association between moderate or strenuous physical activity and reduced fatigue, lesion volumes and relapse rates in children and adolescents with multiple sclerosis. [More]
Kessler Foundation researcher confirms link between sleep disturbances and MS-related fatigue

Kessler Foundation researcher confirms link between sleep disturbances and MS-related fatigue

Kessler Foundation's Lauren Strober, PhD, explores the association of secondary fatigue and sleep disturbances in multiple sclerosis (MS). "Fatigue in multiple sclerosis: a look at the role of poor sleep" was published in Frontiers in Neurology. [More]
Chronic fatigue a long-term problem for testicular cancer survivors

Chronic fatigue a long-term problem for testicular cancer survivors

A Norwegian population-based study reported in the Annals of Oncology has found a rise in the incidence of chronic fatigue a decade or more after treatment in testicular cancer survivors. [More]
Tips for preventing ticks, Lyme disease

Tips for preventing ticks, Lyme disease

When a mosquito decides to dine on your blood, you typically know it - there's pain, itch, and annoyance. Ticks, on the other hand, take a stealthier approach, burrowing into hard-to-spot areas and hanging around for hours or days at a time. [More]
BDSI announces FDA approval of sNDA for new formulation of ONSOLIS (fentanyl buccal soluble film) CII

BDSI announces FDA approval of sNDA for new formulation of ONSOLIS (fentanyl buccal soluble film) CII

BioDelivery Sciences International, Inc. announced the approval by the U.S. Food and Drug Administration of a Supplemental New Drug Application (sNDA) for a new formulation of ONSOLIS (fentanyl buccal soluble film) CII for the management of breakthrough pain in patients with cancer who are opioid tolerant. [More]
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