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Expert creates new evidence-based guideline for managing sickle cell disease

Expert creates new evidence-based guideline for managing sickle cell disease

An expert panel has created a new evidence-based guideline for managing sickle cell disease (SCD), with a strong recommendation for the use of the drug hydroxyurea and transfusion therapy for many individuals with SCD, although high-quality evidence is limited, with few randomized clinical trials conducted for this disease, according to an article in the September 10 issue of JAMA. [More]
Researchers aim to safely and quickly suppress food allergies in human

Researchers aim to safely and quickly suppress food allergies in human

In mice, the answer appears to be "yes," but making sure the same can happen in humans is a task that Fred Finkelman, MD, professor of medicine and pediatrics in the University of Cincinnati's (UC) College of Medicine and a researcher at Cincinnati Children's Hospital Medical Center, is attempting to tackle. [More]
SLU researchers work to prevent several serious infectious diseases

SLU researchers work to prevent several serious infectious diseases

Saint Louis University researchers are attacking influenza on multiple fronts as they search for a universal vaccine that protects people from the flu virus that often mutates year to year with deadly consequences. [More]
State highlights: Democrats consider letting states curb health costs; obesity in America

State highlights: Democrats consider letting states curb health costs; obesity in America

Borrowing a Republican idea, a group including former senior Obama and Clinton advisers is unveiling a novel proposal to let states take the lead in controlling health costs. [More]
Peramivir drug safe, effective at alleviating influenza symptoms

Peramivir drug safe, effective at alleviating influenza symptoms

An analysis of phase 2 and phase 3 clinical trials shows that a single injected dose of the neuraminidase inhibitor (NAI) peramivir is safe and effective at alleviating influenza symptoms, including fever and viral shedding, when administered within 48 hours of the onset of symptoms. [More]
First Edition: September 5, 2014

First Edition: September 5, 2014

Today's headlines include reports of hacker activity at the healthcare.gov health insurance website. [More]
Clinical studies to treat unmet medical need post-transplantation

Clinical studies to treat unmet medical need post-transplantation

A class of biotechnology drugs called monoclonal antibodies is now being tested in clinical studies to treat an unmet medical need post-transplantation, called delayed graft function [More]
Viewpoints: Medicare no longer 'busting' the budget; a 'nightmare' trying to get coverage in D.C.

Viewpoints: Medicare no longer 'busting' the budget; a 'nightmare' trying to get coverage in D.C.

You're looking at the biggest story involving the federal budget and a crucial one for the future of the American economy. Every year for the last six years in a row, the Congressional Budget Office has reduced its estimate for how much the federal government will need to spend on Medicare in coming years. [More]
Researchers develop potential antibody therapy for Sudan ebolavirus

Researchers develop potential antibody therapy for Sudan ebolavirus

Researchers from Albert Einstein College of Medicine of Yeshiva University and other institutions have developed a potential antibody therapy for Sudan ebolavirus (SUDV), one of the two most lethal strains of Ebola. [More]
Researchers report possible therapy that could help treat patients infected with SUDV

Researchers report possible therapy that could help treat patients infected with SUDV

Ebola is a rare, but deadly disease that exists as five strains, none of which have approved therapies. [More]
Actavis reports positive results from ceftazidime-avibactam Phase III studies in cIAI patients

Actavis reports positive results from ceftazidime-avibactam Phase III studies in cIAI patients

Actavis plc today confirmed positive topline results from RECLAIM-1 and -2, pivotal Phase III studies evaluating the potential for the investigational antibiotic, ceftazidime-avibactam as a treatment for adult hospitalized patients with complicated intra-abdominal infections. [More]
Another threat lies in the spread of Chikungunya virus, say experts

Another threat lies in the spread of Chikungunya virus, say experts

While media attention has been focused recently on coronavirus cases in the Arabian peninsula and the Ebola outbreak in West Africa, experts note that another threat lies in the spread of Chikungunya fever, an illness that is transmitted by mosquitoes and can cause fever, joint and muscle pain, headaches, and rashes. While it does not often cause death, the symptoms can be severe and disabling, with no treatment available. [More]
Communications about the benefits of vaccination influence parents' intentions to immunize children

Communications about the benefits of vaccination influence parents' intentions to immunize children

How do parents decide whether to vaccinate their child? In a study designed to formally look at the content of parent-targeted communications about the benefits of vaccination for measles, mumps and rubella, Indiana University School of Medicine investigators report that the framing of these messages influences parents' intentions to immunize their children. [More]
Globavir plans to seek approval, launch novel drug for treatment of Ebola infection

Globavir plans to seek approval, launch novel drug for treatment of Ebola infection

Globavir Biosciences, Inc., a biotechnology company developing therapeutics to treat infectious diseases, has announced intentions to develop its lead drug candidate, GBV006, for the treatment of the current Ebola Virus outbreak in West Africa. Globavir will seek approval for the use of GBV006, a combination of Food and Drug Administration approved drugs, through an established compassionate use regulatory pathway. [More]

Transmission risk of Ebola virus disease during air travel remains low: WHO

The World Health Organization today reiterated its position that the risk of transmission of Ebola virus disease during air travel remains low. [More]
Combination of NASBA and real-time qPCR detects aspergillosis with 100% accuracy

Combination of NASBA and real-time qPCR detects aspergillosis with 100% accuracy

The fungal infection invasive aspergillosis (IA) can be life threatening, especially in patients whose immune systems are weakened by chemotherapy or immunosuppressive drugs. Despite the critical need for early detection, IA remains difficult to diagnose. [More]
Microbiologist receives contract from U.S. DOD to develop vaccine against tularemia

Microbiologist receives contract from U.S. DOD to develop vaccine against tularemia

Microbiologist Karl Klose, a professor in the UTSA College of Sciences' Department of Biology and a member of the South Texas Center for Emerging Infectious Diseases, has received a contract from the U.S. Department of Defense (DOD) to conduct research that would bring scholars one step closer to developing a vaccine against tularemia. [More]
Reducing brain levels of tau protein effectively blocks development of childhood epilepsy

Reducing brain levels of tau protein effectively blocks development of childhood epilepsy

Researchers at the Gladstone Institutes have shown that reducing brain levels of the protein tau effectively blocks the development of disease in a mouse model of Dravet syndrome, a severe intractable form of childhood epilepsy. [More]
Studies detect integrons that cause resistance to various antibiotics

Studies detect integrons that cause resistance to various antibiotics

In Mexico the sale of antibiotics for human consumption is controlled to prevent misuse, although in the veterinary sector failure in the implementation of the Official Mexican Standard NOM-064-ZOO-2000, "Guidelines for veterinarian products prescription", has prompted common bacteria such as Escherichia coli and Salmonella spp to become resistant to regular drugs such as streptomycin, trimethoprim, ampicillin, gentamicin, and tetracycline as a result of excess drug use. [More]
Plan International outlines strategies to combat Ebola outbreak

Plan International outlines strategies to combat Ebola outbreak

The current Ebola outbreak, the most severe and complex in history, is now making its impact felt worldwide. [More]