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Amyloid growth can occur independently of oligomers

Improperly folded proteins are normally destroyed. But in a wide range of diseases, including prion (from proteinaceous and infectious) diseases and neurodegenerative diseases like Parkinson disease and Alzheimer disease, amyloid fibrils, or plaques--misshapen proteins that aggregate into characteristic ropelike configurations--accumulate in tissue.

22 Sep 2004

Jellyfish advance science

Salmon fishermen trolling along the waters off Puget Sound in Washington are often witness to an awesome sight when they haul in their catch: salmon captured in nets that glow brilliantly against the nighttime sky.

16 Sep 2004

Unique technology with the potential to test for hundreds of diseases, cancers and genes in one, cheap, test

Queensland, Australia PhD student Angus Johnston has invented a unique technology with the potential to test for hundreds of diseases, cancers and genes in one, cheap, test. He hopes that within five years the technology will be available in a desktop unit for less than AU$30,000.

10 Sep 2004

Hair growing stem cells may one day provide treatments for human hair conditions

Researchers at the Howard Hughes Medical Institute at The Rockefeller University have isolated stem cells from the skin of a mouse, and showed, for the first time, that an individual stem cell can renew itself in the laboratory and then be used in grafts to produce skin, hair and oil glands.

5 Sep 2004

Bone marrow produces cells that permanently heal wounds

Bone marrow produces cells that not only help fight infection but also permanently heal wounds, according to research at the University of Washington. Previously, researchers had not known that bone marrow contributed to the development of new skin in wounds.

5 Sep 2004

Ultra-sensitive measurement technique shows how biomolecular motors carry out essential tasks

In the human body, hundreds of different types of biomolecular motors help carry out such essential tasks as muscle contraction, moving chromosomes during cell division, and reloading nerve cells so they can repeatedly fire.

30 Aug 2004

More tumour cells in the blood leads to quicker deterioration in women with breast cancer

A new study of women with advanced breast cancer who have more tumor cells circulating in their blood deterioate and die quicker than women with fewer of these cells, according to the researchers from the University of Michigan Comprehensive Cancer Center and other cancer centers throughout the country.

18 Aug 2004

Embryonic stem cell therapy show benefits in rebuilding damaged heart

Despite improvements in earlier diagnosis and treatment, cardiovascular disease is far and away the leading cause of death in the U.S. and the world.

18 Aug 2004

New fluorescent dye technique may provide new insight into how cancerous tumors begin and grow

A technique developed by University of California, San Diego biologists, which uses bright fluorescent dyes to reveal the activity of genes in individual cells of an organism, promises to be a boon to developmental biologists, and may provide new insight into how cancerous tumors begin and grow.

6 Aug 2004

Miniature spectroscopic instruments and software to look at changes that occur within the cells and tissue of the brain

When molecules in cells are stimulated by light, they respond by becoming excited and re-emitting light of varying colors (fluorescence) that can be captured and measured by highly sensitive optical equipment.

2 Aug 2004

First tool to study image brain function at the cellular level

Carnegie Mellon University neuroscientist Alison Barth has developed the first tool to identify and study individual neurons activated in a living animal.

29 Jul 2004

Light-sensitive probe to help doctors spot breast cancer

A light-sensitive probe is being developed to help doctors spot breast cancer in some of the 70,000 American women each year whose malignancies fail to show up in needle biopsies.

26 Jul 2004

Novel tool that can be used to visualize single neurons in living brain tissue

Carnegie Mellon University neuroscientist Alison Barth has developed the first tool to identify and study individual neurons activated in a living animal.

15 Jul 2004

Recent tuberculosis research holds promise for developing a more effective vaccine

Tuberculosis, a mycobacterium that infects human lungs, still claims the lives of about 2 million people every year. Existing vaccines provide questionable protection, and they can even cause disease in individuals with compromised immune systems.

9 Jul 2004

Rabies infections in organ donor and transplant recipients

On June 30, 2004, CDC confirmed diagnoses of rabies in three recipients of transplanted organs and in their common donor, who was found subsequently to have serologic evidence of rabies infection.

2 Jul 2004

Positron emission tomography offers a better way to observe the damage that strokes and neurodegenerative diseases wreak on brain cells

A laser-based microscopy technique may have settled a long-standing debate among neuroscientists about how brain cells process energy

2 Jul 2004

Chromosomal chaos in early embryonic development is linked to abnormalities in cytokinesis and spindle formation

Abnormalities in the spindles (the bi-polar thread like structures that link and pull the chromosomes during cell division) of human embryos before implantation may be the primary reason for many of the chromosome defects observed in early human development

29 Jun 2004

RNA enzyme research may lead to ways of monitoring fat metabolism and might even assist in the search for signs of life on Mars

Research aimed at teasing apart the workings of RNA enzymes eventually may lead to ways of monitoring fat metabolism and might even assist in the search for signs of life on Mars, according to University of Michigan researcher Nils Walter.

29 Jun 2004

Implantable chip could serve as a prosthetic retina for people who suffer from age-related blindness

Where other types of chips use electricity to stimulate nerves, this one instead tickles cells with minute amounts of chemicals. Because nerve cells normally communicate with each other by releasing chemicals known as neurotransmitters, the new device points to a more effective way of treating very delicate tissues, such as those in the eye and in the brain.

24 Jun 2004

Stimulation or drugs that target the pro-opiomelanocortin system will be effective in treating diabetes or obesity

There’s more than one way to slim a cat - at least that’s the hope of University of Florida obesity researchers, who believe pets and even people may someday benefit from gene therapy research aimed at breaking through the biochemical bottleneck that makes many middle-aged mammals gain weight.

17 Jun 2004