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New metal-free methodology for fluorination of aliphatic hydrocarbon bonds

Researchers from the Muñiz group have published a paper in Angewandte Chemie - International Edition presenting a new metal-free methodology for the photo-catalyzed nucleophilic fluorination of aliphatic hydrocarbon bonds.

21 May 2020

A new method to deliver therapeutic proteins inside the body

A new way to deliver therapeutic proteins inside the body uses an acoustically sensitive carrier to encapsulate the proteins and ultrasound to image and guide the package to the exact location required, according to Penn State researchers. Ultrasound then breaks the capsule, allowing the protein to enter the cell.

23 Apr 2020

Researchers develop a unique radiochemical synthesis approach for treating cancer

Radiolabeled molecules, so-called radiotracers, help nuclear physicians to detect and precisely target tumors, which are often developing due to pathological changes in metabolic processes.

7 Apr 2020

Novel MRI contrast agent for early detection of brain metastases

A group of researchers led by Leif Schroeder from the Leibniz-Forschungsinstitut fuer Molekulare Pharmakologie have found a way to detect metastases in certain types of cancer in the brain at an early stage, using only minimal amounts of contrast agent.

19 Mar 2020

Researchers confirm safety of cancer-specific PET probe in first-in-human clinical studies

A group of researchers led by Assistant Professor WATABE Tadashi of the Graduate School of Medicine of Osaka University achieved the stable domestic production of automatic synthesis modules for positron emission tomography (PET) probe F-18 NKO-035, a LAT1-selective amino acid derivative radiolabeled with 18F, confirming its safety in first-in-human clinical studies conducted at Osaka University Hospital in November 2019.

22 Jan 2020

Increasing anti-tumor activity of compound extracted from an Amazon plant

Researchers in Brazil have prepared modified forms of the alkaloids produced by Uncaria guianensis, a woody vine native to the Amazon Rainforest.

31 Oct 2019

Popcorn packaging contains high levels of toxic chemicals

Many chemicals used at home and in various industries use per- and polyfluoroalkyl substances (PFAS). Several studies have traced these substances in materials used for packaging foods, such as microwavable bags and food containers.

13 Oct 2019

New study explores the chemistry and alarming history of fast-acting insecticide

A new study in the Journal of the American Chemical Society explores the chemistry as well as the complicated and alarming history of DFDT, a fast-acting insecticide.

11 Oct 2019

Osaka University Hospital begins clinical research for prostate cancer diagnosis using PET imaging

Osaka University Hospital began Japan's first clinical research for diagnosis of prostate cancer using PET (positron emission tomography) scan results in September 2019.

7 Oct 2019

Common bacterium can chew through PFAS and other difficult-to-remove pollutants

In a series of lab tests, a relatively common soil bacterium has demonstrated its ability to break down the difficult-to-remove class of pollutants called PFAS, researchers at Princeton University said.

19 Sep 2019

New class of radiopharmaceuticals offer fresh perspective on cancer imaging, theranostics

Research presented at the 2019 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging describes a new class of radiopharmaceuticals, named radiohybrids, that offer a fresh perspective on cancer imaging and radioligand therapy.

26 Jun 2019

Researchers report new way for creating tracers used with medical imaging

In an advance for medical imaging, scientists from University of North Carolina Lineberger Comprehensive Cancer Center have discovered a method for creating radioactive tracers to better track pharmaceuticals in the body as well as image diseases, such as cancer, and other medical conditions.

21 Jun 2019

Characterizing Small Molecules with NMR

In this interview, Marcel Lachenmann describes the importance of characterizing small molecules in the pharma, food and polymer industry and how NMR achieves this.

From Oxford Instruments NMR 11 Apr 2019

Expanding range and functionality of radiotracers for improved disease diagnosis

Biomedical imaging has revolutionized medicine, granting doctors a window into miniscule molecular and cellular processes inside the body. An EU-funded project helped to expand the view, developing innovative radiochemistry concepts and techniques that could lead to earlier diagnosis of diseases - saving lives.

4 Apr 2019

Newly engineered nanoscale protein micelles can be tracked by MRI

A team of researchers from New York University has engineered nanoscale protein micelles capable of both delivering chemotherapeutic drugs and of being tracked by magnetic resonance imaging.

21 Mar 2019

Researchers discover facile method for introduction of fluorine atoms into organic molecules

The vast majority of pharmaceuticals employed in the treatment of human diseases are of an organic nature, meaning that the active component is a molecule (or a combination of several molecules) that is constituted of carbon and hydrogen atoms.

6 Mar 2019

Dental flossing and other consumer behaviors contribute to elevated levels of PFAS in the body

A new study suggests certain types of consumer behaviors, including flossing with Oral-B Glide dental floss, contribute to elevated levels in the body of toxic PFAS chemicals. PFAS are water- and grease-proof substances that have been linked with numerous health problems.

8 Jan 2019