Frontotemporal Dementia News and Research

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Study explores cellular alterations in six distinct neurodegenerative diseases

A perplexing range of neurodegenerative diseases are known to attack distinct regions of the brain, causing severe cognitive and motor deficit.

21 Dec 2022

Previous traumatic brain injury may potentially affect frontotemporal dementia risk

A recent study from the University of Eastern Finland shows that previous traumatic brain injury may potentially affect the risk of frontotemporal dementia.

19 Dec 2022

Study reveals wasteosomes as markers of chronic glymphatic system insufficiency

A new study led by researchers from the University of Barcelona shows that wasteosomes -;structures that act as containers for brain waste products-; indicate a malfunction of the glymphatic system, a recently discovered system that is an important brain-cleaning mechanism.

30 Nov 2022

Two new studies identify potential risk factors associated with frontotemporal dementia

Two recent studies from the University of Eastern Finland show that educational background and previous traumatic brain injury may potentially affect the risk of frontotemporal dementia.

24 Nov 2022

Scientists develop RNA-targeting strategy to repair genetic cause of ALS and dementia

Scientists at UF Scripps Biomedical Research have developed a potential medicine for a leading cause of ALS and dementia that works by eliminating disease-causing segments of RNA. The

22 Nov 2022

Study provides new insights into genetic form of frontotemporal dementia

Dementia encompasses a range of neurodegenerative conditions that lead to memory loss and cognitive deficiencies and affect some 55 million people worldwide.

28 Oct 2022

TDP-43 can be useful biomarker for identifying neuropathological subtypes of frontotemporal dementia

Frontotemporal dementia (FTD) is one of the most common causes of progressive dementia in working-age people.

20 Oct 2022

UC San Diego receives $1.3 million grant to understand the role of misfolded tau proteins in dementia

Researchers at the University of California San Diego have received a $1.3 million grant from the W. M. Keck Foundation for a project that could help scientists better understand the role misfolded tau proteins play in causing neurodegenerative diseases like dementia, which may lead to more effective drug therapies.

16 Aug 2022

The Alzheimer’s Association recognizes seven researchers for contributions to the field of dementia science

The Alzheimer’s Association will present seven awards at the Alzheimer’s Association International Conference 2022, recognizing researchers for their varied expertise, noteworthy achievements and innovative contributions to the field of Alzheimer’s and dementia science.

1 Aug 2022

Experts release appropriate use recommendations for Alzheimer’s disease blood biomarkers

Alzheimer’s disease blood biomarkers (BBMs) may revolutionize the diagnosis of Alzheimer’s in the future, but are not yet ready for widespread use, according to a newly-published article by leading international clinicians and researchers convened by the Alzheimer’s Association.

31 Jul 2022

New center aims to accelerate research into biomarkers of neurodegenerative diseases

A new center established at Washington University School of Medicine in St. Louis aims to accelerate research into biomarkers of neurodegenerative conditions such as Huntington's and Parkinson's diseases, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS) and the so-called tauopathies, a group that includes Alzheimer's disease along with rarer diseases such as frontotemporal dementia, corticobasal syndrome and progressive supranuclear palsy.

13 Jul 2022

DZNE and Intravacc receive € 2.5 million EU funding to develop a prototype ALS vaccine

DZNE and Intravacc B.V., a world leading contract development and manufacturing organization (CDMO) of preventive and therapeutic vaccines, have been awarded a funding of € 2.5 million from the European Union (EIC Transition Grant) to further develop a prototype ALS vaccine, including process development, scale-up, and toxicology study.

6 Jul 2022

MRI-based machine learning approach can accurately predict Alzheimer’s disease

The research uses machine learning technology to look at structural features within the brain, including in regions not previously associated with Alzheimer's.

20 Jun 2022

Studies find breakthrough SARS-CoV-2 Infections are more likely in cancer and Alzheimer's patients

Breakthrough COVID-19 cases resulting in infections, hospitalizations and deaths are significantly more likely in cancer and Alzheimer's patients, according to two new studies from researchers at the Case Western Reserve University School of Medicine.

23 May 2022

Antibiotic rifampicin attenuates C9orf72-linked dementia in genetically modified mice

What did Stephen Hawking and Mao Zedong have in common? They both suffered from Amyotrophic Lateral Sclerosis (ALS), a cure for which remains elusive. Scientists from Osaka Metropolitan University took an important step toward prevention of ALS and another brain disorder called Frontotemporal dementia (FTD) with their research on the effects of the antibiotic rifampicin on genetically modified mice.

23 May 2022

People with young-onset Alzheimer’s experience faster symptom progression than older counterparts

People diagnosed with Alzheimer’s disease at a younger age will experience faster symptom progression than their older counterparts, a new study has found, potentially causing their support systems to fall behind.

16 May 2022

Study finds promising new treatment for patients with behavioral variant frontotemporal dementia

A Monash University led study has found a promising new treatment for patients with behavioural variant frontotemporal dementia, the second most common form of dementia in the under 60s – resulting in a stabilising of what would normally be escalating behavioural issues, and a slowing of brain shrinkage due to the disease.

6 May 2022

Brain folds formed during fetal development could affect age at onset in frontotemporal dementia

Frontotemporal dementia begins relatively early compared to other forms of dementia. We still know relatively little about what causes the disease, however, new research from Lund University in Sweden shows that the folds in the brain that are formed in the latter stages of pregnancy could have an impact on the age at which the disease takes hold.

3 May 2022

Single-cell genome sequencing provides a new way to think about Alzheimer’s disease

Alzheimer's disease is marked by a loss of functional neurons in the brain. But what causes this loss? Through single-cell genome sequencing, researchers at Boston Children's Hospital, Brigham and Women's Hospital, and the Broad Institute show that people with Alzheimer's have an abundance of newly acquired mutations in their neurons -; more than people of the same age without Alzheimer's, and enough to disable genes important to brain function.

20 Apr 2022

Inhibiting key signaling pathway in immune cells may slow down Alzheimer's disease

Inhibiting an important signaling pathway in brain-resident immune cells may calm brain inflammation and thereby slow the disease process in Alzheimer's and some other neurodegenerative diseases, suggests a study by Weill Cornell Medicine investigators.

14 Apr 2022