Frontotemporal Dementia News and Research

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Researchers develop new blood test for Alzheimer's disease

A new blood test for Alzheimer's disease has been developed under the leadership of researchers at the University of Gothenburg, Sweden. The method is based on measuring a specific variant of tau protein in ordinary blood samples, which makes the test relatively simple and cheap to perform.

23 Apr 2020

Tracking tau protein yields insight into possible treatments for neurodegenerative diseases

In the fight against neurodegenerative diseases such as frontotemporal dementia, Alzheimer's and Chronic Traumatic Encephalopathy, the tau protein is a major culprit.

1 Apr 2020

Study uncovers a new childhood-onset neurodegenerative disorder

A study has uncovered a new neurodegenerative disorder in which children experience developmental regression and severe epilepsy.

21 Mar 2020

Protective brain-cell housekeeping mechanism may also be involved in regulating sleep

An important biological mechanism that is thought to protect brain cells from neurodegenerative diseases such as Alzheimer's and Parkinson's may also be involved in regulating sleep, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

12 Mar 2020

Nearly $4 million to fund drug discovery research for Alzheimer's, other dementia

The Alzheimer's Association and the Rainwater Charitable Foundation have joined forces again to fund drug discovery research towards finding therapies for Alzheimer's disease, frontotemporal degeneration, and other tauopathies.

4 Mar 2020

New blood test could be deployed in primary care setting for people with memory issues

A blood test that may eventually be done in a doctor's office can swiftly reveal if a patient with memory issues has Alzheimer's disease or mild cognitive impairment and can also distinguish both conditions from frontotemporal dementia.

2 Mar 2020

Research suggests new approach to block tau pathology in FTLD, Alzheimer's

The protein β-arrestin-2 increases the accumulation of neurotoxic tau tangles, a cause several forms of dementia, by interfering with removal of excess tau from the brain, a new study by the University of South Florida Health Morsani College of Medicine found.

17 Feb 2020

Diagnosed with dementia, she documented her wishes. They said no.

When she worked on the trading floor of the Chicago Board Options Exchange, long before cellphone calculators, Susan Saran could perform complex math problems in her head. Years later, as one of its top regulators, she was in charge of investigating insider trading deals.

21 Jan 2020

A class of antibiotics could be potential treatment for frontotemporal dementia

Researchers at the University of Kentucky's College of Medicine have found that a class of antibiotics called aminoglycosides could be a promising treatment for frontotemporal dementia.

10 Jan 2020

A physically and mentally active lifestyle can slow familial frontotemporal dementia

A physically and mentally active lifestyle confers resilience to frontotemporal dementia (FTD), even in people whose genetic profile makes the eventual development of the disease virtually inevitable, according to new research by scientists at the UC San Francisco Memory and Aging Center.

8 Jan 2020

Oligomerix and Feinstein Institutes publish preclinical data of Alzheimer's disease treatment

Oligomerix, Inc., a privately held company pioneering the development of tau oligomer inhibitors for Alzheimer's disease and related neurodegenerative disorders, and the Feinstein Institutes for Medical Research announced today the publication of preclinical data demonstrating that an oral small molecule drug inhibits the formation of neurotoxic tau oligomers in an animal model of tau aggregation most relevant to AD.

26 Nov 2019

Extra virgin olive oil boosts brain power

Researchers from the Lewis Katz School of Medicine at Temple University have found that extra virgin olive oil (EVOO) could help boost brain power and help halt the progression of the effects of aging on the brain. The study was published in the latest issue of the journal Aging Cell, and it was titled, “Extra virgin olive oil improves synaptic activity, short‐term plasticity, memory, and neuropathology in a tauopathy model.”

26 Nov 2019

Inflammatory processes drive progression of neurodegenerative brain diseases

Inflammation drives the progression of neurodegenerative brain diseases and plays a major role in the accumulation of tau proteins within neurons.

20 Nov 2019

TDP-43 study could speed up the diagnosis and treatment of ALS

A new study suggests that TDP-43 may be used as a biomarker in the diagnosis and treatment of amyotrophic lateral sclerosis (ALS).

30 Oct 2019

Patterns of Alzheimer's-related damage differ by subtype and age of onset, study finds

Despite decades of scientific scrutiny, Alzheimer's disease researchers have yet to work out its cause or treatment. Understanding what underlies its three distinct subtypes is thought to be a promising new research avenue.

29 Oct 2019

Semantic memory deficits linked to eating disorders in patients with dementia

For the first time, it has been shown that deficits of semantic memory, an ability we use to recognize objects and use them correctly, are involved in specific eating disorders shared by patients suffering from dementia.

17 Oct 2019

Improved antibody validation

Antibodies are used in a variety of clinical and research situations to examine the structure and function, and distribution of proteins. However, many researchers have found a lack of specificity in the functioning of these antibodies. This means that any work conducted using these antibodies will not yield reliable results.

16 Oct 2019

NIH-funded research consortium aims to advance treatments for frontotemporal lobar degeneration

The National Institutes of Health has awarded a five-year, multi-investigator research grant expected to total more than $63 million to Mayo Clinic and the University of California, San Francisco, to advance treatments for frontotemporal lobar degeneration

16 Oct 2019

Research reveals increased inflammatory activity in patients with frontotemporal dementia

Recent research from the University of Eastern Finland revealed increased inflammatory activity in a subgroup of patients with frontotemporal dementia. Increased inflammation was associated with parkinsonism symptoms and more rapid disease progression.

15 Oct 2019

How dementia spreads: new study says it’s through neural networks

Scientists have found out a way to forecast the spread of brain atrophy, using prior research that shows how brain networks connect with each other to form a continuously linked pathway.

14 Oct 2019