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Biological breakthrough that could offer new hope in the fight against liver cancer

Professor John Mayer and Dr Simon Dawson, in collaboration with colleagues at Japan's Kyoto University, have discovered the function of a new liver oncoprotein - or cancer causing protein - which could be the first step to finding effective new treatments for the deadly illness.

21 Jul 2005

Project to help millions of people avoid starvation

Scientists at the University of Bath will be taking part in an international £4.2 million ($7.5 million) research project that could help millions of people avoid starvation.

21 Jul 2005

Definitive proof that Ab42 is the culprit molecule that underlies the pathology of Alzheimer's disease

One puzzle in Alzheimer's disease (AD) research is why mice engineered to have the abnormal protein underlying the disease in humans show little pathology of the disease. Specifically, such mice are genetically altered to overproduce mutant human amyloid precursor protein (APP).

21 Jul 2005

New research suggests that accumulation of amyloid-beta peptides in cerebral blood vessels causes vascular damage in Alzheimer's disease

New research suggests that accumulation of amyloid-â peptides in cerebral blood vessels, as opposed to the brain itself, may be a more important pathological mediator of Alzheimer's disease. Two independent yet related articles describe such findings in the August issue of The American Journal of Pathology.

21 Jul 2005

Researchers have doubled the potency of a protein that drives blood to clot

...according to research to be published in the July 26 edition of Biochemistry. The study results may have profound implications for the treatment of hemophilia, the inherited blood disorder that causes easy or excessive bleeding in 30,000 Americans.

20 Jul 2005

Protein found in fat cells is a newly discovered cause of insulin resistance

A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has shown that a protein found in fat cells is a newly discovered cause of insulin resistance, establishing a previously unidentified molecular link between obesity and type 2 diabetes and offering a potential new target for the development of drugs to treat diabetes.

20 Jul 2005

University of Florida researcher finds way to explore role of microRNAs in specific tissue

University of Florida researchers have learned how to selectively shut down a flyweight-sized genetic molecule that packs a heavyweight punch, a discovery that may help doctors better understand cancer, birth defects and other health problems.

20 Jul 2005

Variant of a common protein plays a primary role in Type 2 diabetes and obesity

Scientists in France and the United States report that a variant of a common protein plays a primary role in Type 2 diabetes and obesity, key features of the "insulin resistance syndrome" that affects more than 50 million people in this country and a similar number in Europe.

19 Jul 2005

Pineapple stems that show anti-tumour activity

Scientists at the Queensland Institute of Medical Research (QIMR) have discovered two molecules from pineapple stems that show anti-tumour activity in laboratory studies. One molecule called CCS blocks a protein called Ras, which is defective in approximately 30% of all cancers. The other molecule called CCZ, stimulates the body's own immune system to target and kill cancer cells.

19 Jul 2005

Important find will help design appropriate screening and therapy for women carrying fetuses impaired in their growth

In her research, Dr. Andree Gruslin encountered many pregnant women who could not carry their fetuses to term because the placenta, and in turn the fetus, were too small. In once case, she followed a woman who had had eight consecutive miscarriages due to this condition. Thanks to this latest discovery, she now understands why.

19 Jul 2005

Results demonstrate the safety and tolerability of ABthrax treatment for Anthrax infection

Human Genome Sciences has announced that results published in the current issue of Clinical Infectious Diseases demonstrate that the first investigational agent against anthrax infection to be evaluated in a clinical study since the 2001 anthrax attacks in the United States, is safe, well tolerated and achieves the blood levels predicted by relevant animal models as necessary to afford significant protection from the lethal effects of the anthrax toxin

19 Jul 2005

New and more efficient target for antiangiogenic therapy

Scientists now have a more complete understanding of how cancer cells send signals to surrounding tissues to promote development of the blood supply needed to support tumor growth.

19 Jul 2005

Hormonal signaling systems and their role in sex drive

Two University of Edinburgh professors from the Centre for Integrative Physiology describe how "our understanding of how the brain processes information is undergoing a radical shift as we begin to recognize the implications of hormonal signaling systems within the brain itself," explained Gareth Leng.

19 Jul 2005

Minimally invasive colorectal surgery may have a less pronounced inflammatory response

Minimally invasive colorectal surgery may have a less pronounced inflammatory response and less of a suppressing effect on the immune system than conventional surgery, resulting in a possible reduction in post-operative complications, according to a study in the July issue of Archives of Surgery.

19 Jul 2005

Studies explore genetic interactions between two well-known tumor suppressor proteins, PTEN and TSC2

Two papers in the August 1 issue of Genes & Development explore the genetic interactions between two well-known tumor suppressor proteins, PTEN and TSC2.

19 Jul 2005

New discovery could help in the fight against cancer

University of Michigan researchers have figured out one more component in cancer cells' aggressive growth - and hope that knowledge can help kill the cells.

18 Jul 2005

Tamiflu may treat avian flu virus

Experiments in mice show that an antiviral drug currently used against annual influenza strains also can suppress the deadly influenza virus that has spread from birds to humans, killing dozens of people in Vietnam, Cambodia and Thailand since early 2004.

18 Jul 2005

Researchers have identified a protein that is crucially involved in how our memories are stored and processed

University of Queensland researchers have identified a protein that is crucially involved in how our memories are stored and processed, paving the way for new strategies to treat conditions certain mental disorders.

18 Jul 2005

Scientists determine the structures of eight proteins in just 10-20 days per protein

A University at Buffalo scientist created a stir in 2003 when he announced a much faster, more precise and far less expensive method of obtaining nuclear magnetic resonance (NMR) data to map a protein's atomic structure. Genomics researchers were fascinated, but some also were a bit skeptical.

18 Jul 2005

Startling discovery about the properties of human bone

The scientists describe their results - finding a sort of "glue" in human bone - in the cover story of the August issue of the international scientific journal, Nature Materials. The article was published on-line on July 17. It describes how healthy bone resists fracture and how unhealthy bone fractures at the molecular level.

18 Jul 2005

G Protein News and Research

Biological breakthrough that could offer new hope in the fight against liver cancer

Project to help millions of people avoid starvation

Definitive proof that Ab42 is the culprit molecule that underlies the pathology of Alzheimer's disease

New research suggests that accumulation of amyloid-beta peptides in cerebral blood vessels causes vascular damage in Alzheimer's disease

Researchers have doubled the potency of a protein that drives blood to clot

Protein found in fat cells is a newly discovered cause of insulin resistance

University of Florida researcher finds way to explore role of microRNAs in specific tissue

Variant of a common protein plays a primary role in Type 2 diabetes and obesity

Pineapple stems that show anti-tumour activity

Important find will help design appropriate screening and therapy for women carrying fetuses impaired in their growth

Results demonstrate the safety and tolerability of ABthrax treatment for Anthrax infection

New and more efficient target for antiangiogenic therapy

Hormonal signaling systems and their role in sex drive

Minimally invasive colorectal surgery may have a less pronounced inflammatory response

Studies explore genetic interactions between two well-known tumor suppressor proteins, PTEN and TSC2

New discovery could help in the fight against cancer

Tamiflu may treat avian flu virus

Researchers have identified a protein that is crucially involved in how our memories are stored and processed

Scientists determine the structures of eight proteins in just 10-20 days per protein

Startling discovery about the properties of human bone

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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