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Researchers discover pathway contributing to fatty liver disease

Researchers from Karolinska Institutet have found a protein that is a critical regulator in the development of fatty liver disease in mice, according to a study published in the journal Nature Communications.

11 Apr 2019

Researchers describe mathematical model as key to developing effective drugs for brain disorders

A collaboration between researchers from the UAB Institute of Neurosciences and the pharmaceutical company GlaxoSmithKline, published in March in Trends in Pharmacological Sciences, describes a mathematical model to quantify the activity of biased G-protein-coupled receptors.

28 Mar 2019

Promising gene therapy could restore vision in humans

It was surprisingly simple. University of California, Berkeley, scientists inserted a gene for a green-light receptor into the eyes of blind mice and, a month later, they were navigating around obstacles as easily as mice with no vision problems.

15 Mar 2019

Researchers use optogenetic tool to control, visualize receptor signals in neural cells

Using a novel optogenetic tool, researchers have successfully controlled, reproduced and visualized serotonin receptor signals in neural cells. To this end, they modified a photosensitive membrane receptor in the eye, namely melanopsin.

15 Feb 2019

Study takes a step closer to understanding the body's response to opioid painkillers

Researchers have taken a step closer to understanding the body's response to opioid painkillers such as morphine and fentanyl, which could lead to the development of safer opioid drugs.

21 Jan 2019

Study shows how a novel regulatory mechanism serves as key biomarker for diabetes

A recent study led by researchers in Texas A&M University's department of nutrition and food science shows how a novel regulatory mechanism serves as an important biomarker for the development of diabetes, as well as a potential therapeutic target for its prevention.

20 Dec 2018

Developing the Next Generation of Water-soluble DREADDs

An interview with James Flanaghan, discussing the uses of DREADDs in neurobiological research and the advantages of water-soluble ligands.

From Hello Bio 19 Dec 2018

IONTAS founder and pioneer in phage display technology attends Nobel Prize Award Ceremony

Dr. John McCafferty celebrates the success of phage display technology with Nobel Prize in Chemistry Laureates.

From FairJourney Biologics 12 Dec 2018

Study shows how cellular waste disposal processes also promote inflammation

A study conducted at the University of California has revealed how cells use G-protein-coupled receptors (GPCRs) and their waste disposal systems to mediate inflammation.

19 Sep 2018

Study gives new insights into how cells leverage GPCRs to control inflammation

G-protein-coupled receptors are everywhere in our bodies. They are embedded in our cell membranes, where they act as signal transducers, allowing cells to respond to their external environments.

19 Sep 2018

Dopamine receptor study opens door to targeted treatments for neuropsychiatric disorders

New work from researchers at Columbia University Vagelos College of Physicians and Surgeons sheds light on how dopamine receptors signal within cells, opening the door for more targeted--and more tolerable--therapeutics to treat an array of neuropsychiatric disorders.

4 Sep 2018

Research provides drug developers with much needed insight into serotonin receptor

Serotonin, known as the "happiness" neurotransmitter, is a chemical found in the body responsible for feelings of well-being. But serotonin isn't the only chemical that binds to the 13 serotonin receptors found on the surface of cells. Far from it. Many approved drugs also bind to serotonin receptors.

21 Aug 2018

UAB study shows how ion channel differentiates newborn and mature neurons in the brain

The dentate gyrus of the hippocampus is part of the brain that helps form memories. It is also one of just two areas in the adult brain where new neurons are continuously formed.

13 Aug 2018

New study explores human T cell function under inflammatory conditions

The Marshall University School of Pharmacy, in collaboration with the Marshall University Joan C. Edwards School of MedicineGenomics Core, recently released a new study that explores human T cell function under inflammatory conditions.

31 Jul 2018

New study finds way to help treat alcohol addiction and ease withdrawal symptoms

According to a new study by Scripps Research scientists, activating a receptor found in brain cells may help treat alcohol addiction and ease some withdrawal symptoms. The researchers studied the effects of activating the receptor in alcohol-addicted rats and reported the results today in the journal eNeuro.

27 Jun 2018

G Protein News and Research

Researchers discover pathway contributing to fatty liver disease

Researchers describe mathematical model as key to developing effective drugs for brain disorders

Promising gene therapy could restore vision in humans

Researchers use optogenetic tool to control, visualize receptor signals in neural cells

Study takes a step closer to understanding the body's response to opioid painkillers

Study shows how a novel regulatory mechanism serves as key biomarker for diabetes

Developing the Next Generation of Water-soluble DREADDs

IONTAS founder and pioneer in phage display technology attends Nobel Prize Award Ceremony

Study shows how cellular waste disposal processes also promote inflammation

Study gives new insights into how cells leverage GPCRs to control inflammation

Dopamine receptor study opens door to targeted treatments for neuropsychiatric disorders

Research provides drug developers with much needed insight into serotonin receptor

UAB study shows how ion channel differentiates newborn and mature neurons in the brain

New study explores human T cell function under inflammatory conditions

New study finds way to help treat alcohol addiction and ease withdrawal symptoms

Researchers identify new anti-inflammatory drug target

Genetic differences can influence efficiency of medicines

Discovery of key protein’s structure may help improve drug design

Sonic Hedgehog helps solve mysteries of Parkinson's disease

Two studies set groundwork for new avenues to treat influenza and anthrax poisoning

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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