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Synthetic compound targets enzyme that supports survival and dissemination of metastatic cells

Cancer can most often be successfully treated when confined to one organ. But a greater challenge lies in treating cancer that has metastasized, or spread, from the primary tumor throughout the patient's body.

17 Oct 2017

Study could pave way for more effective cancer therapies

Many tumors possess mechanisms to avoid destruction by the immune system. For instance, they misuse the natural "brakes" in the immune defense mechanism, which normally prevent an excessive immune response. Researchers at the University of Bonn have now been able to take off one of these brakes.

17 Oct 2017

Using AFM to study cell mechanics and function

My lab, broadly speaking, is interested in trying to understand interactions between cells and materials. Those could be materials that are present within living tissue or materials that we use for engineering purposes to try to do something of technological or therapeutic interest.

From Bruker Nano Surfaces and Metrology 17 Oct 2017

CHOP researchers discover key differences among gene fusions in childhood brain tumors

Researchers investigating pediatric low-grade gliomas, the most common type of brain tumor in children, have discovered key biological differences in how mutated genes combine with other genes to drive this childhood cancer.

17 Oct 2017

Findings reveal how seizures can have lasting detrimental effects on memory

Although it's been clear that seizures are linked to memory loss and other cognitive deficits in patients with Alzheimer's disease, how this happens has been puzzling. In a study published in the journal Nature Medicine, a team of researchers reveals a mechanism that can explain how even relatively infrequent seizures can lead to long-lasting cognitive deficits in animal models.

16 Oct 2017

Father's diet before sex could contribute to changes in the offspring’s health, study reveals

A new study, conducted by the University of Cincinnati (UC) biology professors Michal Polak and Joshua Benoit, suggests that a father's nutrition could play a similar role to the mother’s nutrition in his offspring’s health. Researchers from the University of Sydney's Charles Perkins Centre and the University of Western Australia also collaborated on the study.

16 Oct 2017

BU researcher wins NIH award for research on molecular mechanism of senile cardiac amyloidosis

Lawreen H. Connors, PhD, associate professor of pathology and laboratory medicine and biochemistry at Boston University School of Medicine, is the recipient of a National Institutes of Health High Priority, Short-Term Project Award, for her research "molecular mechanism of senile cardiac amyloidosis."

16 Oct 2017

IGeneX launches three new tests to aid diagnosis of Borreliosis

IGeneX Inc., a CLIA and New York-approved Reference Laboratory, specializing in testing for tick-borne diseases, is pleased to announce the launch of three new tests that are more inclusive and specific for aiding in diagnosis of Borreliosis (Lyme Disease and Tick-Borne Relapsing Fever, Borreliosis).

16 Oct 2017

Study identifies new biomarker for depression in diabetes

A study published in the current issue of Psychotherapy and Psychosomatic has identified a biomarker for depression in diabetes. Findings of epidemiological studies have shown an overall 2-fold increased prevalence of depression in patients with type 2 diabetes compared with the general population worldwide.

16 Oct 2017

Investigating new cancer therapy candidates with live-cell imaging

There are two main things that we've worked on in the lab as regards to drug studies. One is identifying new combinations of drugs, and working on why a combination of drugs should work better than each alone.

From Sartorius 16 Oct 2017

Fluence Analytics launches new patented protein and polymer stability monitoring product

Fluence Analytics, a manufacturer of realtime, industrial and laboratory monitoring systems, today announced the launch of ARGEN, a patented protein and polymer stability monitoring product. By utilizing continuous light scattering measurements, ARGEN yields a unique information stream which reduces discovery and formulation and development times.

16 Oct 2017