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In anatomy, a ganglion (plural ''ganglia'') is a biological tissue mass, most commonly a mass of nerve cell bodies. Cells found in a ganglion are called ganglion cells, though this term is also sometimes used to refer specifically to retinal ganglion cells.
BrightFocus offers grants to 55 scientists for Alzheimer's disease and vision research

BrightFocus offers grants to 55 scientists for Alzheimer's disease and vision research

BrightFocus Foundation, a nonprofit organization funding cutting-edge, innovative research on Alzheimer's disease and the vision diseases of glaucoma and macular degeneration, today announced the recipients of new research grant awards, offered to 55 scientists in 19 U.S. states, the District of Columbia, and five foreign countries. [More]
Dental pulp stem cells can protect retinal ganglion cells from death following injury

Dental pulp stem cells can protect retinal ganglion cells from death following injury

Researchers at the University of Birmingham, UK, led by Dr. Ben Scheven, Dr. Wendy Leadbeater and Ben Mead have discovered that stem cells isolated from the teeth, termed dental pulp stem cells (DPSC), can protect retinal ganglion cells (RGCs) from death following injury and promote regeneration of their axons along the optic nerve. [More]
Alternative disposal process in optic nerve cells has implications for neurodegenerative diseases

Alternative disposal process in optic nerve cells has implications for neurodegenerative diseases

Biologists have long considered cells to function like self-cleaning ovens, chewing up and recycling their own worn out parts as needed. [More]
New study on transmitophagy process may help treat diverse disorders

New study on transmitophagy process may help treat diverse disorders

It's broadly assumed that cells degrade and recycle their own old or damaged organelles, but researchers at University of California, San Diego School of Medicine, The Johns Hopkins University School of Medicine and Kennedy Krieger Institute have discovered that some neurons transfer unwanted mitochondria - the tiny power plants inside cells - to supporting glial cells called astrocytes for disposal. [More]
Researchers take step toward restoring natural, high-fidelity vision to blind people

Researchers take step toward restoring natural, high-fidelity vision to blind people

In laboratory tests, researchers have used electrical stimulation of retinal cells to produce the same patterns of activity that occur when the retina sees a moving object. Although more work remains, this is a step toward restoring natural, high-fidelity vision to blind people, the researchers say. [More]
Researchers discover atypical type of retina cell that plays more critical role in vision

Researchers discover atypical type of retina cell that plays more critical role in vision

A type of retina cell plays a more critical role in vision than previously known, a team led by Johns Hopkins University researchers has discovered. [More]
Retinal measurements associated with Parkinson’s disease duration

Retinal measurements associated with Parkinson’s disease duration

The inner retinal layers in the eyes of patients with Parkinson’s disease are thinner than those of healthy people’s eyes, except for the inner nuclear layer, which is thicker, show the results of a prospective study involving the latest optical coherence tomography methods. [More]
Researchers identify possible mechanism for re-growing damaged nerve fibres in central nervous system

Researchers identify possible mechanism for re-growing damaged nerve fibres in central nervous system

A new discovery suggests it could one day be possible to chemically reprogram and repair damaged nerves after spinal cord injury or brain trauma. [More]
Photoreactive compounds open new routes to treatment of neurological diseases

Photoreactive compounds open new routes to treatment of neurological diseases

Photoreactive compounds developed by scientists of Ludwig-Maximilians-Universitaet (LMU) in Munich directly modulate nerve-cell function, and open new routes to the treatment of neurological diseases, including chronic pain and certain types of visual impairment. [More]
Newly developed compound may allow blind see light

Newly developed compound may allow blind see light

Progressive degeneration of photoreceptors-the rods and cones of the eyes-causes blinding diseases such as retinitis pigmentosa and age-related macular degeneration. While there are currently no available treatments to reverse this degeneration, a newly developed compound allows other cells in the eye to act like photoreceptors. As described in a study appearing in the February 19 issue of the Cell Press journal Neuron, the compound may be a potential drug candidate for treating patients suffering from degenerative retinal disorders. [More]
Randomized trial shows injecting anesthetic near nerve bundle reduces troublesome hot flashes

Randomized trial shows injecting anesthetic near nerve bundle reduces troublesome hot flashes

​Injecting a little anesthetic near a nerve bundle in the neck cut troublesome hot flashes significantly, shows a new randomized, controlled trial published online today in Menopause, the journal of The North American Menopause Society (NAMS). [More]
Study shows endoplasmic reticulum stress plays important role in diabetic retinopathy

Study shows endoplasmic reticulum stress plays important role in diabetic retinopathy

Endoplasmic reticulum stress is closely involved in the early stage of diabetic retinopathy. According a study published in the Neural Regeneration Research (Vol. 8, No. 33, 2013), endoplasmic reticulum stress played an important role in the hyperglycemia-induced death of ganglion cells and impairment of retinal microvessels. [More]
Melatonin plays major role in pain transmission

Melatonin plays major role in pain transmission

Accumulating research indicates that melatonin has a major role in pain transmission and has an ultra-sensitizing effect. Dr. Fang Huang and colleagues from Sun Yat-sen University in China for the first time located the distribution of melatonin receptor 1 in the caudal spinal trigeminal nucleus. [More]
Research: Neuropeptides may serve as index for evaluating early peripheral nerve injury

Research: Neuropeptides may serve as index for evaluating early peripheral nerve injury

Substance P and calcitonin gene-related peptide are the main neuropeptides in peripheral nerve ganglia, which can anterogradely transmit nociceptive information to the central nervous system. [More]

Transient receptor potential channel A1 causes calcitonin gene-related peptide release in neurons

Transient receptor potential channel A1 is one of the important transducers of noxious stimuli in the primary afferents, which may contribute to generation of neurogenic inflammation and hyperalgesia. [More]
Adding corticosteroid fluocortolone with standard therapy improves visual acuity in NAION patients

Adding corticosteroid fluocortolone with standard therapy improves visual acuity in NAION patients

Nonarteritic anterior ischemic optic neuropathy is one of the leading causes of sudden and irreversible loss of vision in older adults. In a prospective randomized trial of 60 patients with NAION, investigators have shown that the addition of the corticosteroid fluocortolone to standard therapy significantly improves both short- and long-term visual acuity, especially when given soon after the onset of symptoms. Their results are published in Restorative Neurology and Neuroscience. [More]
Researchers study link between vision loss and Alzheimer's disease

Researchers study link between vision loss and Alzheimer's disease

An international team of researchers studying the link between vision loss and Alzheimer's disease report that the loss of a particular layer of retinal cells not previously investigated may reveal the disease's presence and provide a new way to track disease progression. [More]

Cellectricon introduces Dynaflow Resolve Temperature Control system for ion channel research

Cellectricon, a leading provider of advanced cell-based screening technologies and services, launches the Dynaflow Resolve Temperature Control system at Neuroscience 2013 (San Diego), booth #933. [More]

Oligomeric proanthocyanidin has protective effect on retinal ganglion cells, shows study

The death of retinal ganglion cells is a hallmark of many optic neurodegenerative diseases such as glaucoma and retinopathy. Oxidative stress is one of the major reasons to cause the cell death. [More]

Cellectricon to demonstrate Cellaxess technology at Neuroscience 2013

Cellectricon, a leading provider of advanced cell-based screening technologies and services, will be presenting new data at Neuroscience 2013, 9-13 November, San Diego (USA). [More]