Ganglion News and Research

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In anatomy, a ganglion (plural ''ganglia'') is a biological tissue mass, most commonly a mass of nerve cell bodies. Cells found in a ganglion are called ganglion cells, though this term is also sometimes used to refer specifically to retinal ganglion cells.

Proteasomes: Expanding roles beyond cellular waste management

The typical job of the proteasome, the garbage disposal of the cell, is to grind down proteins into smaller bits and recycle some of those bits and parts.

13 Apr 2024

Tiam1 inhibition mitigates morphine tolerance and hyperalgesia in mouse model

Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems -; prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same pain relief, and paradoxically, prolonged use also can create an extreme sensitivity to pain, called hyperalgesia.

9 Apr 2024

Ultra-processed foods linked to higher glaucoma risk, study warns

Study finds a significant relationship between the highest intake of ultra-processed foods, especially sweets, and an increased risk of developing glaucoma among Spanish university graduates, highlighting the importance of dietary quality for ocular health.

8 Apr 2024

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Recombinant adeno-associated virus (rAAV)-based genetic applications to treat human diseases.

5 Apr 2024

Study uncovers key genes and cell types that may affect pathogenesis of primary open-angle glaucoma

Although primary open-angle glaucoma (POAG) is the leading cause of blindness in people over the age of 55, there remains no cure for the disease and its biological mechanisms are not well understood.

16 Feb 2024

Johns Hopkins scientists unravel mystery of retinal cell communication

Working with mammalian retinal cells, neuroscientists at Johns Hopkins Medicine have shown that, unlike most light-sensing cells (photoreceptors) in the retina, one special type uses two different pathways at the same time to transmit electrical "vision" signals to the brain.

25 Jan 2024

IU researchers aim to develop a new therapy for glaucoma

Researchers at Indiana University School of Medicine are using a novel approach to hopefully develop a new therapy for glaucoma, a complex disease that eventually leads to blindness, thanks to a new five-year, $2 million R01 grant from the National Eye Institute.

8 Jan 2024

New research debunks color's influence on the human internal clock

Vision is a complex process. The visual perception of the environment is created by a combination of different wavelengths of light, which are decoded as colors and brightness in the brain.

22 Dec 2023

Does tinnitus cause hearing loss in normal hearing individuals?

Whether cochlear neural degeneration occurs in normal-hearing individuals with tinnitus.

4 Dec 2023

Revolutionizing pain management: Study highlights effectiveness of low-dose local anesthetics

The therapeutic efficacy of low-dose local anesthetics (LAs) in various clinical conditions, highlighting gaps in current research for future exploration.

23 Nov 2023

Image-guided procedure may alleviate parosmia symptoms in long COVID patients

Using an image-guided minimally invasive procedure, researchers may be able to restore the sense of smell in patients who have suffered with long-COVID, according to research being presented next week at the annual meeting of the Radiological Society of North America.

20 Nov 2023

Researchers identify a promising new strategy for glaucoma cell replacement therapy

Glaucoma is one of the leading causes of blindness worldwide, and vision loss, due to the loss of retinal ganglion cells (RGCs), cannot currently be reversed with any treatment.

17 Nov 2023

New insights into migraine etiology: the role of hepatocyte growth factor

The causal links between pro-inflammatory cytokine expression and migraine.

10 Nov 2023

Mast cell receptor linked to alcohol withdrawal-associated headaches

Researchers investigate the role of the mast-cell-specific receptor Mas-related G-protein-coupled receptor B2 (MrgprB2) in alcohol-withdrawal-induced headaches.

2 Nov 2023

Managing menopause: The 2023 toolkit for healthcare practitioners

The authors of the revised 2023 Toolkit extracted key recommendations from professional guidelines and positions as well as consensus statements on menopause and related conditions that have emerged since 2014.

1 Nov 2023

Revolutionary approach links protein analysis and single-cell study to uncover disease mechanisms

Integrated liquid-biopsy proteomics with single-cell transcriptomics from ocular cell types.

24 Oct 2023

SARS-CoV-2 RNA found in ocular tissues at autopsy, despite minimal inflammation

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), infects tissues throughout the human body, including the eye.

10 Oct 2023

Advanced neuroimaging reveals surprising link between glaucoma and Alzheimer's disease

The overlap in clinical and magnetic resonance imaging (MRI) findings between Alzheimer's disease and glaucoma.

9 Oct 2023

Flash therapy may offer a practical option to delay the circadian clock in shift workers and jet travelers

Researchers examined whether flash therapy, given during sleep, changed the sleep architecture to shift the human circadian clock.

6 Sep 2023

Study finds examining retinal structure could provide markers for Parkinson disease

A new paper examined the retinal data from Parkinson disease patients in attempt to identify disease markers.

24 Aug 2023