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Inflammatory response prompted by secretion of cytokines causes acid reflux damage in GERD patients

Inflammatory response prompted by secretion of cytokines causes acid reflux damage in GERD patients

The "acid" in "acid reflux" may not be the direct cause of damage to the esophagus as previously suspected, according to researchers at UT Southwestern Medical Center and Dallas VA Medical Center. [More]
Acid suppression drugs frequently prescribed for high-risk newborns, study shows

Acid suppression drugs frequently prescribed for high-risk newborns, study shows

Since 2006, several published studies have associated the use of some acid suppression medications in hospitalized high-risk babies with infections, necrotizing enterocolitis and increased risk of death. Those medications - histamine-2 receptor antagonists, such as ranitidine (Zantac and others), and proton pump inhibitors, such as esomeprazole (Nexium and others) - were originally approved by the U.S. Food and Drug Administration for use in adults and older children. [More]
Newly identified molecular pathway could lead to new treatments for reflux, incontinence disorders

Newly identified molecular pathway could lead to new treatments for reflux, incontinence disorders

Researchers at UMass Medical School have identified a new molecular pathway critical for maintaining the smooth muscle tone that allows the passage of materials through the digestive system. [More]
Zurampic (lesinurad) approved to treat high levels of hyperuricemia associated with gout

Zurampic (lesinurad) approved to treat high levels of hyperuricemia associated with gout

The U.S. Food and Drug Administration today approved Zurampic (lesinurad) to treat high levels of uric acid in the blood (hyperuricemia) associated with gout, when used in combination with a xanthine oxidase inhibitor (XOI), a type of drug approved to reduce the production of uric acid in the body. [More]
People who experience persistent heartburn despite over-the-counter treatments need to check with their doctors

People who experience persistent heartburn despite over-the-counter treatments need to check with their doctors

If Thanksgiving makes you wince at the thought of impending heartburn pain, you are probably not alone. But if you experience heartburn more than twice a week despite over-the-counter treatments, a Jefferson expert wants you to check with your doctor. Gastroesophageal Reflux Disease (GERD) Awareness Week is observed each year during the week of Thanksgiving, a fitting time as Americans prepare to indulge in the holiday season. [More]
Stony Brook Medicine expert shares tips to minimize heartburn during holiday season

Stony Brook Medicine expert shares tips to minimize heartburn during holiday season

The holiday season is upon us and most days and nights will be filled with delicious festivities! However, with millions of Americans suffering from heartburn, fear may set in when anticipating these celebrations. [More]
EndoGastric Solutions announces assignment of relative value units for new CPT code covering TIF procedure

EndoGastric Solutions announces assignment of relative value units for new CPT code covering TIF procedure

EndoGastric Solutions® (EGS), a leader in incisionless procedural therapy for gastroesophageal reflux disease (GERD), today announced the Federal Register has posted coding and payment information specific to the new Current Procedural Terminology (CPT)® code covering the Transoral Incisionless Fundoplication (TIF®) procedure. [More]
Medigus announces CMS’ publication of fee schedules for endoscopic fundoplication procedures under CPT code 43210 effective January 2016

Medigus announces CMS’ publication of fee schedules for endoscopic fundoplication procedures under CPT code 43210 effective January 2016

Medigus Ltd., a medical device company developing minimally invasive endosurgical tools and a leader in direct visualization technology, today announced that following the American Medical Association’s (AMA) decision earlier this year to create a new Category I Current Procedural Terminology (CPT®) code for esophagogastric fundoplast... [More]
IPF-PRO Registry data sheds light on characteristics of people with idiopathic pulmonary fibrosis

IPF-PRO Registry data sheds light on characteristics of people with idiopathic pulmonary fibrosis

Boehringer Ingelheim Pharmaceutical, Inc. today announced initial results of the first 49 people enrolled in the IPF-PRO Registry, which shed light on characteristics of people with IPF at the time of diagnosis. [More]
Loyola gastroenterologist provides tips to IBS patients for healthy living

Loyola gastroenterologist provides tips to IBS patients for healthy living

More than 20 percent of the US population lives with irritable bowel syndrome (IBS) and for many Americans it is an ongoing challenge. But when it comes to treatment, old advice from Mom was right. Often, the key is to eat right and go outside and play. [More]

Camber Pharmaceuticals releases generic version of Nexium (Esomeprazole) capsules

Camber Pharmaceuticals is pleased to announce that it has launched Esomeprazole Magnesium Delayed-Release Capsules, 20 mg and 40 mg, which is the generic version of Nexium (Esomeprazole) capsules from AstraZeneca Pharmaceuticals. The product is indicated for the treatment of heartburn, gastroesophageal reflux disease (GERD), stomach ulcers, and for a damaged esophagus. [More]
New, FDA-approved device provides minimally invasive approach to chronic GERD

New, FDA-approved device provides minimally invasive approach to chronic GERD

Approximately 20 million Americans will experience some type of gastroesophageal reflux disease, or GERD, in their lives. In some cases, patients suffer resulting heart burn or acid regurgitation so severe that they require surgery to repair damage to their esophagus. [More]
Lannett enters into definitive agreement to purchase KU for $1.23 billion

Lannett enters into definitive agreement to purchase KU for $1.23 billion

Lannett Company, Inc. today announced that it has signed a definitive agreement to purchase Kremers Urban Pharmaceuticals Inc., the U.S. specialty generic pharmaceuticals subsidiary of global biopharmaceuticals company UCB S.A., for $1.23 billion, plus potential contingency payments. [More]
Scientists elucidate chemical process behind eosinophilic esophagitis

Scientists elucidate chemical process behind eosinophilic esophagitis

Scientists from the D'Or Institute of Research and Education, the Federal University of Rio de Janeiro and the Yale University School of Medicine have elucidated the chemical process behind a mysterious gastrointestinal disease that is becoming more frequent every day: the eosinophilic esophagitis (EoE), also known as the "asthma of the esophagus". [More]
Women who conceive babies through IVF at increased risk of experiencing GORD

Women who conceive babies through IVF at increased risk of experiencing GORD

Women who give birth to babies conceived by in-vitro fertilisation (IVF) are at increased risk of experiencing long-term symptoms of gastro-oesophageal reflux disease (GORD), according to the results of a study published in the UEG Journal. [More]
Mylan announces launch of Esomeprazole Magnesium Delayed-release Capsules USP in U.S.

Mylan announces launch of Esomeprazole Magnesium Delayed-release Capsules USP in U.S.

Mylan N.V. today announced the U.S. launch of Esomeprazole Magnesium Delayed-release Capsules USP, 20 mg and 40 mg, which is the generic version of AstraZeneca's Nexium. [More]
Proton pump inhibitors linked to increased risk of heart attack

Proton pump inhibitors linked to increased risk of heart attack

People who use proton pump inhibitors (PPIs) are up to 21% more likely to experience a heart attack than people who do not use the antacids, according to researchers from Stanford University, California. [More]
NGS mutational testing can help detect patients with Barrett's esophagus

NGS mutational testing can help detect patients with Barrett's esophagus

Barrett's esophagus (BE) develops in a subset of patients with gastroesophageal reflux disease (GERD) and can increase the risk of developing cancer of the esophagus. Although periodic surveillance for cancer is recommended for BE patients, these examinations may fail to identify pre-cancerous dysplasia and early cancers. [More]
Long-term treatment of GERD: an interview with Chris Rowland, CEO, Medigus

Long-term treatment of GERD: an interview with Chris Rowland, CEO, Medigus

To control reflux symptoms, many people take acid-controlling medications such as Proton Pump Inhibitors, or PPIs. The FDA, however, has issued warnings over the frequent or long-term continued use of PPIs... [More]
Studies support use of ThyraMIR and ThyGenX to improve detection of benign/malignant thyroid nodules

Studies support use of ThyraMIR and ThyGenX to improve detection of benign/malignant thyroid nodules

Data will be presented at both Digestive Disease Week (DDW) and the American Association of Clinical Endocrinologists (AACE) annual medical meetings. [More]
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