Gastroesophageal Reflux Disease News and Research

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Gastroesophageal reflux disease (GERD) is a more serious form of gastroesophageal reflux (GER), which is common. GER occurs when the lower esophageal sphincter (LES) opens spontaneously, for varying periods of time, or does not close properly and stomach contents rise up into the esophagus. GER is also called acid reflux or acid regurgitation, because digestive juices—called acids—rise up with the food. The esophagus is the tube that carries food from the mouth to the stomach. The LES is a ring of muscle at the bottom of the esophagus that acts like a valve between the esophagus and stomach.

NYU Langone Health expands outpatient network in Suffolk County with new locations, specialty services

As part of its mission to enhance access to quality healthcare where people live and work, NYU Langone Health continues to grow its outpatient network in Suffolk County on Long Island with new locations and specialty services.

6 Oct 2022

WTC responders with chronic conditions appear to have severe Covid-19 and long-term sequelae

A study of 1,280 patients treated and monitored at the Stony Brook World Trade Center Health and Wellness Program who also contracted Covid-19 reveals that the responders who have suffered from chronic conditions from WTC exposures and the experience of the 911 tragedy appear to have more infection severity and long-term sequelae than responders who do not have chronic diseases resulting from WTC exposures.

13 Jun 2022

Novel diagnostic platform offers hope for early detection of cancer in patients with Barrett’s esophagus

On a mission to increase early detection of esophageal cancer, University of Colorado (CU) Cancer Center member Sachin Wani, MD, is leading a study to see if a novel diagnostic platform can help endoscopists better identify the disease in patients with a condition called Barrett's esophagus.

8 Feb 2022

Are our bowel habits written in our DNA?

In this interview, News-Medical talks to Dr. Mauro D’Amato about how there could be clues about the regularity of bowel movements within our genes.

24 Dec 2021

Acid pH enhances SARS-CoV-2 infection by up-regulating ACE2 receptor

A new study published in the journal Frontiers of Medicine indicated that Barrett's esophagus (BE) and gastroesophageal reflux disease (GERD) may represent novel comorbidities associated with SARS-CoV-2 disease. A previous study had estimated that in the United States, 5.6% of adults have BE, a disease where esophageal squamous mucosa gets damaged by GERD.

12 Sep 2021

Weight loss drug Wegovy approved by FDA

The U.S. Food and Drug Administration (FDA) has approved Wegovy (semaglutide) injection (2.4 mg once weekly) as a chronic weight management treatment in obese or overweight adults with a weight-related condition (such as high blood pressure, type 2 diabetes, or high cholesterol), when used along with calorie restriction and physical activity. Wegovy, is a more potent version of Novo Nordisk's diabetes drug semaglutide.

4 Jun 2021

New technique may result in earlier and easier identification of patients with Barrett's esophagus

A new technique for sampling and testing cells from Barrett's esophagus (BE) patients could result in earlier and easier identification of patients whose disease has progressed toward cancer or whose disease is at high risk of progressing toward cancer, according to a collaborative study by investigators at Case Western Reserve University and Johns Hopkins Kimmel Cancer Center (JHKCC).

23 Mar 2021

Gastroesophageal reflux disease is linked with higher risks of larynx and esophageal cancers

Results from a large prospective study indicate that gastroesophageal reflux disease (GERD), which also causes heartburn symptoms, is linked with higher risks of various cancers of the larynx (or voice box) and esophagus.

22 Feb 2021

Gene variants may provide clues to successful treatment of pediatric eosinophilic esophagitis

A group of three gene variants, commonly inherited together, may provide clues to more successful treatment of pediatric eosinophilic esophagitis (EoE), a chronic inflammation of the food pipe often confused with gastroesophageal reflux disease (GERD).

16 Oct 2020

Researchers highlight when antireflux surgery is needed to treat GERD after endoscopy

Researchers report a growing awareness of gastroesophageal reflux problems among patients who undergo endoscopic, nonsurgical treatment for esophageal achalasia, frequently requiring future surgical intervention.

8 Apr 2020

Chronic cough could be eased with new drug

A pair of studies have shown that chronic cough and its distressing symptoms could be eased with the help of a new drug. Also, the drug does not have side effects that can restrict its use, explain the researchers. The results of the two studies are published in The Lancet Respiratory Medicine, and the European Respiratory Journal, respectively.

26 Feb 2020

$Investigational drug reduces heartburn severity in patients with refractory GERD$

Investigational drug reduces heartburn severity in patients with refractory GERD

An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests.

26 Feb 2020

Gastroesophageal reflux disease may affect nearly a third of U.S. adults every week

Gastroesophageal reflux disease (GERD), a digestive disorder that causes hearburn and other uncomfortable symptoms, may affect nearly a third of U.S. adults each week, and most of those who take certain popular medications for it still have symptoms, according to a new Cedars-Sinai study.

19 Dec 2019

Tips for enjoying your holiday parties without feeling the sting of acid reflux

With the holidays approaching, you may have visions of sugar plums dancing in your head. However, if you're living with GERD, gastroesophageal reflux disease, you should enjoy those sugar plums in moderation and be sure to manage your GERD triggers.

25 Nov 2019

Study could change clinical treatment for patients with unmanaged heartburn

A study published today in The New England Journal of Medicine found that in patients seen for heartburn unresponsive to treatment with Proton Pump Inhibitors, an extensive, systematic workup revealed truly PPI-refractory and reflux-related heartburn in only a minority of cases.

17 Oct 2019

FDA warns about Ranitidine containing known carcinogen NDMA

The United States Food and Drug Administration have issued a warning regarding some substances present in a brand of Ranitidine that could be carcinogenic. In their first warning issued on the 13th of this month, the FDA warns that one of the brands of Ranitidine, Zantac is said to contain a nitrosamine impurity called N-nitrosodimethylamine (NDMA) at low levels. NDMA is a known carcinogen, the report reads based on lab data and is also found in the environment, food and water the report adds.

26 Sep 2019

Simple genetic test may boost response rates in children with eosinophilic esophagitis

Personalized medicine - where the proper medicine and proper dose are used for the individual patient - moved a step closer to reality for children suffering from eosinophilic esophagitis, an inflammation of the food pipe often caused by an allergic reaction to certain foods.

12 Sep 2019

$Early exposure to antacids could put infants at risk for bone fractures during childhood$

Early exposure to antacids could put infants at risk for bone fractures during childhood

Infants who are given antacids in their first year of life are more likely to fracture a bone later as a child, according to a new study published June 7 in Pediatrics.

11 Jun 2019

New research provides welcomed news for countless patients taking PPIs

For patients taking proton pump inhibitors to treat gastroesophageal disease (GERD) or other acid-related conditions, new research puts safety concerns to rest.

7 Jun 2019

Common acid reflux drugs tied to elevated risk for kidney disease

Proton pump inhibitors, which include well-known brand names Prilosec, Nexium and Prevacid, are among the most commonly prescribed medications in the world. Approximately 10 percent of adults in the United States take these drugs for frequent heartburn, acid reflux and gastroesophageal reflux disease.

19 Feb 2019