Gastrointestinal Cancer News and Research

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Gastrointestinal cancer refers to malignant conditions of the gastrointestinal tract, including the esophagus, stomach, liver, biliary system, pancreas, bowels, and anus.

Identifying subtype of colorectal cancer may help oncologists determine most effective treatment

Colorectal cancer is the second leading cause of cancer death in the U.S., expected to cause about 51,000 deaths in 2019. But until now, it was unclear which drugs were most effective for which patients.

12 Jun 2019

Study highlights the need to educate oncologists about molecular profiling

A questionnaire aimed at assessing how well community oncologists understand "molecular profiling" results from tumor specimens found that 69 percent of participants either said they don't know the answers, or they responded incorrectly.

31 May 2019

Study links heartburn drugs to fatal cases of heart, kidney disease and gastrointestinal cancer

Extended use of popular drugs to treat heartburn, ulcers and acid reflux has been associated with an increased risk of premature death. However, little has been known about the specific causes of death attributed to the drugs.

30 May 2019

Biomarker may help predict first treatment option for metastatic colorectal cancer patients

Foundational research by a City of Hope physician-scientist and his colleagues could one day help metastatic colorectal cancer patients decide whether to choose immunotherapy or chemotherapy as their first treatment option.

2 May 2019

American Gastroenterological Association announces 2019 recipients of annual recognition awards

The American Gastroenterological Association (AGA) has announced the 2019 recipients of the annual recognition awards, given in honor of outstanding contributions and achievements in gastroenterology.

4 Feb 2019

New model could predict personalized waiting time for progression in colorectal cancer

An evolutionary model utilizing serial blood samples from patients with advanced colorectal cancer treated with anti-EGFR therapies in a phase II trial could predict personalized waiting time for progression.

30 Aug 2018

Major bleeding associated with subsequent cancer diagnoses

Bleeding in patients treated with anticoagulants should stimulate a search for cancer, according to late breaking results from the COMPASS trial presented today at ESC Congress 2018.

28 Aug 2018

Aspirin appears to cause major bleeds and have no effect on cancers

Aspirin prevented serious vascular events in patients with diabetes who did not already have cardiovascular disease, but it caused almost as many major bleeds and there was no effect on cancers.

27 Aug 2018

Study shows increased risk of cancer among US flight attendants

A new study from Harvard T.H. Chan School of Public Health has revealed that several types of cancer are more common among US flight attendants than they are among the general population.

26 Jun 2018

Researchers to test two-pronged approach in humans to treat advanced colorectal cancer

For the first time in humans, researchers will test a two-pronged approach to treat advanced stage colorectal cancer, potentially increasing life expectancy.

22 May 2018

New faster, streamlined method for bowel cancer detection and treatment

Researchers at the South Australian Health and Medical Research Institute (SAHMRI) and the University of Adelaide have discovered a faster, more cost-effective way to determine which DNA mutations cause human bowel cancer.

17 Apr 2018

Computational approach can help identify chemoresistant potential targets in cancer stem cells

In cancer, one of the most important features is the methylation of deoxycytosine to form 5-methylcytosine (5mC). DNA methylation is a process by which methyl groups (structural units of organic compounds consisting of three hydrogen atoms bonded to a carbon atom) are added to the DNA molecule.

30 Jan 2018

Long-term night shift work among women may increase risk of cancers

Night shift work was associated with women having an increased risk of breast, skin, and gastrointestinal cancer, according to a meta-analysis.

8 Jan 2018

Smartphone app can detect worsening symptoms during cancer treatments

Cancer patients receiving chemotherapy can be remotely monitored using their smartphone sensors and an algorithm that detects worsening symptoms based on objective changes in patient behavior, according to a new study from the University of Pittsburgh and UPMC Hillman Cancer Center.

20 Dec 2017

Researchers reveal previously unknown mechanism that inhibits cells' ability to develop into tumors

CANCER RESEARCH Danish researchers have just presented a previously unknown mechanism that inhibits the ability of cells to develop into cancer cells. Their findings have important implications for the understanding of how cancer starts, and how to improve the treatment of illness in the future.

15 Dec 2017

Genetic diversity of tumor tissues can be barrier to precision medicine in gastric and esophageal cancers

A new study focused on describing genetic variations within a primary tumor, differences between the primary and a metastatic branch of that tumor, and additional diversity found in tumor DNA in the blood stream could help physicians make better treatment choices for patients with gastric and esophageal adenocarcinoma.

15 Nov 2017

Four main genes linked to survival of pancreatic cancer patients

Alterations in four main genes are responsible for how long patients survive with pancreatic cancer, according to a new study in JAMA Oncology.

3 Nov 2017

Research suggests novel approach to treating deadly pancreatic cancer

Pancreatic cancer is now the third leading cause of cancer mortality. Its incidence is increasing in parallel with the population increase in obesity, and its five-year survival rate still hovers at just 8 to 9 percent.

16 Aug 2017

Study reveals radiation therapy advantage for patients with right-sided colorectal tumors

For patients with colorectal cancer that has metastasized to the liver, having a primary tumor on the left side, as opposed to the right side of the colon, is known to be a significant advantage in terms of treatment response.

3 Jul 2017

Liquid biopsies provide more information about disease course in non-invasive manner

A new study, to be presented at the ESMO 19th World Congress on Gastrointestinal Cancer, shows that so-called "liquid biopsies", blood tests that detect circulating tumour DNA (ctDNA), may not only sound an early alert that a treatment's effect is diminishing, but may also help explain why -sometimes offering clues about what to do next.

30 Jun 2017