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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.
Researchers develop mouse model to improve basic research on Ebola treatments, vaccines

Researchers develop mouse model to improve basic research on Ebola treatments, vaccines

Researchers at the University of North Carolina at Chapel Hill and colleagues have developed the first genetic strain of mice that can be infected with Ebola and display symptoms similar to those that humans experience. [More]
Scientists develop new system to treat a host of genetic conditions

Scientists develop new system to treat a host of genetic conditions

As potential next-generation therapeutics and research tools, few life sciences technologies hold more promise than genome-editing proteins – molecules that can be programmed to alter specific genes in order to treat or even cure genetic diseases. [More]
New consensus guidelines for toxicity testing of oligonucleotide-based therapeutics

New consensus guidelines for toxicity testing of oligonucleotide-based therapeutics

Oligonucleotide-based therapeutics present unique challenges when it comes to testing their potential to cause reproductive and developmental harm. New consensus guidelines for toxicity testing that take into consideration the combined chemical and biological characteristics of these novel biopharmaceuticals are presented in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers. [More]
Two major studies newly implicate dozens of genes in autism

Two major studies newly implicate dozens of genes in autism

Two major genetic studies of autism, led in part by UC San Francisco scientists and involving more than 50 laboratories worldwide, have newly implicated dozens of genes in the disorder. The research shows that rare mutations in these genes affect communication networks in the brain and compromise fundamental biological mechanisms that govern whether, when, and how genes are activated overall. [More]
Molecular profiling reveals potential therapeutic targets for lung cancer

Molecular profiling reveals potential therapeutic targets for lung cancer

Analysis of 607 small cell lung cancer (SCLC) lung tumors and neuroendocrine tumors (NET) identified common molecular markers among both groups that could reveal new therapeutic targets for patients with similar types of lung cancer, according to research presented today at the 2014 Chicago Multidisciplinary Symposium in Thoracic Oncology. [More]
Einstein-Montefiore researchers to present latest finding on aging research at GSA 2014

Einstein-Montefiore researchers to present latest finding on aging research at GSA 2014

Investigators at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center will present their latest aging research at the Gerontological Society of America's 67th Annual Scientific Meeting. [More]
TriStar² S multi-label microplate reader now available with monochromator technology

TriStar² S multi-label microplate reader now available with monochromator technology

With the TriStar² S Berthold Technologies introduces monochromator technology in its basic multi-label microplate reader. [More]
Insilico Medicine, CCARL and Plantbiosis partner to advance research on aging

Insilico Medicine, CCARL and Plantbiosis partner to advance research on aging

Through this unique partnership, the Baltimore-based Insilico Medicine and Lethbridge-based CCARL will provide expertise in aging research and build on the personalized medicine and drug discovery platforms OncoFinder and GeroScope to develop new systems for age-related diseases. [More]
Moffitt researcher uncovers new approach to treat cancer

Moffitt researcher uncovers new approach to treat cancer

The scientific community has made significant strides in recent years in identifying important genetic contributors to malignancy and developing therapeutic agents that target altered genes and proteins. A recent approach to treat cancer called synthetic lethality takes advantage of genetic alterations in cancer cells that make them more susceptible to certain drugs. [More]
SCN clock isn't necessary to align body rhythms with light-dark cycle, study reveals

SCN clock isn't necessary to align body rhythms with light-dark cycle, study reveals

Circadian clocks regulate functions ranging from alertness and reaction time to body temperature and blood pressure. New research published in the November 2014 issue of The FASEB Journal further adds to our understanding of the circadian rhythm by suggesting that the suprachiasmaticus nucleus (SCN) clock, a tiny region of the hypothalamus considered to be the body's "master" timekeeper, is not necessary to align body rhythms with the light-dark cycle. [More]
Study: Nearly 5% of U.S. children affected by fetal alcohol spectrum disorders

Study: Nearly 5% of U.S. children affected by fetal alcohol spectrum disorders

Nearly 5 percent of U.S. children may be affected by fetal alcohol spectrum disorders, according to a new study co-authored by Sanford Research's Gene Hoyme, M.D., and Amy Elliott, Ph.D., and published by Pediatrics. [More]
Researchers discover link between seizures and migraines

Researchers discover link between seizures and migraines

Seizures and migraines have always been considered separate physiological events in the brain, but now a team of engineers and neuroscientists looking at the brain from a physics viewpoint discovered a link between these and related phenomena. [More]
UAlberta researchers discover link between pulmonary hypertension, diabetes and cancer

UAlberta researchers discover link between pulmonary hypertension, diabetes and cancer

A UAlberta team has discovered that a protein that plays a critical role in metabolism, the process by which the cell generates energy from foods, is important for the development of pulmonary hypertension, a deadly disease. [More]
Growth hormone worthwhile treatment in hypochondroplasia

Growth hormone worthwhile treatment in hypochondroplasia

Researchers report that recombinant human growth hormone can improve growth in children with hypochondroplasia. [More]
Insufficient Th1 polarisation blocks RCC vaccine efficacy

Insufficient Th1 polarisation blocks RCC vaccine efficacy

A lack of a clinical response to an allogenic gene-modified renal cell cancer vaccine may be due to insufficient type 1 T-helper cell polarisation, show results of a gene expression profiling study. [More]
Study on papillary thyroid carcinoma to be presented at 84th Annual Meeting of the ATA

Study on papillary thyroid carcinoma to be presented at 84th Annual Meeting of the ATA

The prevalence of papillary thyroid carcinoma (PTC), the most common type of thyroid cancer, is increasing rapidly. New research to determine the impact of radioactive iodine (RAI) therapy on survival in PTC, describing a novel blood test able to detect circulating BRAFV600E-positive tumor DNA, and identifying a long non-coding RNA specifically associated with the thyroid that is down-regulated in PTC compared to normal thyroid tissue in patient-derived clinical specimens and cell cultures will be featured in oral presentations delivered at the 84th Annual Meeting of the American Thyroid Association, October 29-November 2, 2014, in Coronado, California. [More]
BloodCenter of Wisconsin announces availability of cancer mutation HemeOnc Panel

BloodCenter of Wisconsin announces availability of cancer mutation HemeOnc Panel

BloodCenter of Wisconsin's Diagnostic Laboratories today announced the availability of a comprehensive cancer mutation HemeOnc Panel using next generation sequencing (NGS) technology. The NGS panel developed by BloodCenter of Wisconsin is designed to detect variants in 30 genes that are either prognostic or diagnostic for 10 different myeloid hematologic malignancies. [More]
New research findings on Graves' disease to be highlighted at ATA meeting

New research findings on Graves' disease to be highlighted at ATA meeting

A unique mouse model of Graves' disease, an autoimmune disorder that causes hyperthyroidism, and new research findings that may help improve the treatment of Graves' disease will be highlighted in oral and poster presentations at the 84th Annual Meeting of the American Thyroid Association, October 29-November 2, 2014, in Coronado, California. [More]
Prof. Mary-Claire King receives 2014 Lasker-Koshland Special Achievement Award in Medical Science

Prof. Mary-Claire King receives 2014 Lasker-Koshland Special Achievement Award in Medical Science

At a ceremony held in New York City on September 19, 2014, leading geneticist and humanitarian Prof. Mary-Claire King, the American Cancer Society Professor of Genome Sciences and Medicine at the University of Washington in Seattle and 2008 Honorary Doctor of Philosophy of Tel Aviv University, was awarded the 2014 Lasker-Koshland Special Achievement Award in Medical Science. [More]
Golden Jubilee National Hospital holds performance review in public

Golden Jubilee National Hospital holds performance review in public

Today, the Golden Jubilee National Hospital held its Annual Review, demonstrating that they have continued to lead the way in safe, effective and person centred care for the NHS in Scotland. [More]