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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.
Nano-sized discovery helps explain bipolar disorder

Nano-sized discovery helps explain bipolar disorder

A nano-sized discovery by Northwestern Medicine® scientists helps explain how bipolar disorder affects the brain and could one day lead to new drug therapies to treat the mental illness. [More]
MIT researchers develop new way to model effects of cancer-causing genetic mutations

MIT researchers develop new way to model effects of cancer-causing genetic mutations

Sequencing the genomes of tumor cells has revealed thousands of genetic mutations linked with cancer. However, sifting through this deluge of information to figure out which of these mutations actually drive cancer growth has proven to be a tedious, time-consuming process. [More]
Longer looks: Obamacare in the midterm campaign; watching Ebola mutate; lessons on dying

Longer looks: Obamacare in the midterm campaign; watching Ebola mutate; lessons on dying

According to Kantar Media, a firm that tracks political advertising, health care is the main subject of campaign ads, especially Republican ones. Obamacare is unpopular-;over half of Americans disapprove of it. Republicans talk about it constantly on the campaign trail, though not as intemperately as they did during their own party's primaries. Democrats scarcely mention it (10/18). [More]
New test could help physicians predict people who are at early stages of sepsis

New test could help physicians predict people who are at early stages of sepsis

A new test, developed by University of British Columbia researchers, could help physicians predict within an hour if a patient will develop severe sepsis so they can begin treatment immediately. [More]
Human trial of second investigational Ebola vaccine candidate under way

Human trial of second investigational Ebola vaccine candidate under way

Human testing of a second investigational Ebola vaccine candidate is under way at the National Institutes of Health's Clinical Center in Bethesda, Maryland. [More]
Scientists use innovative exome sequencing strategy to identify new gene associated with ALS

Scientists use innovative exome sequencing strategy to identify new gene associated with ALS

Using an innovative exome sequencing strategy, a team of international scientists led by John Landers, PhD, at the University of Massachusetts Medical School has shown that TUBA4A, the gene encoding the Tubulin Alpha 4A protein, is associated with familial amyotrophic lateral sclerosis (ALS), a fatal neurological disorder also known as Lou Gehrig's Disease. [More]
Study identifies new signaling pathway that leads to inflammatory bone erosion in RA patients

Study identifies new signaling pathway that leads to inflammatory bone erosion in RA patients

A new study by researchers at Hospital for Special Surgery identifies a new signaling pathway that contributes to the development and progression of inflammatory bone erosion, which occurs in patients with rheumatoid arthritis (RA). Rheumatoid arthritis is a systemic inflammatory autoimmune disease that affects millions of adults worldwide. [More]
YEDA and XL-protein sign deal to commercialize PASylated IFN superagonis

YEDA and XL-protein sign deal to commercialize PASylated IFN superagonis

YEDA Research and Development Company Ltd., the technology transfer arm of the Weizmann Institute of Science, Israel, and XL-protein GmbH, Germany, a privately owned biopharmaceutical company, have signed a business collaboration agreement to commercialize a PASylated interferon superagonist -- PAS-YNSα8 -- which has been jointly developed by scientists at the Weizmann Institute and XL-protein. [More]
Scientists identify potent inhibitors to combat common obesity gene

Scientists identify potent inhibitors to combat common obesity gene

Individuals who are genetically predisposed to obesity may soon have a therapeutic solution to combat their condition. A research team led by scientists from the National University of Singapore (NUS) has identified several potent inhibitors that selectively target FTO, the common fat mass and obesity-associated gene. [More]
Finding could help improve treatment of hearing loss caused by noise, normal aging

Finding could help improve treatment of hearing loss caused by noise, normal aging

Scientists have restored the hearing of mice partly deafened by noise, using advanced tools to boost the production of a key protein in their ears. [More]
New study reveals how cancer becomes drug resistant over time

New study reveals how cancer becomes drug resistant over time

Like a colony of bacteria or species of animals, cancer cells within a tumor must evolve to survive. A dose of chemotherapy may kill hundreds of thousands of cancer cells, for example, but a single cell with a unique mutation can survive and quickly generate a new batch of drug-resistant cells, making cancer hard to combat. [More]
Aspirin can improve efficacy of schizophrenia treatments

Aspirin can improve efficacy of schizophrenia treatments

A new study shows that some anti-inflammatory medicines, such as aspirin, estrogen, and Fluimucil, can improve the efficacy of existing schizophrenia treatments. This work is being presented at the European College of Neuropsychopharmacology conference in Berlin. [More]
Newborns of mothers who smoke during pregnancy have altered stress hormones, DNA

Newborns of mothers who smoke during pregnancy have altered stress hormones, DNA

Researchers from The Miriam Hospital have studied the effects of smoking during pregnancy and its impact on the stress response in newborn babies. Their research indicates that newborns of mothers who smoke cigarettes during pregnancy show lower levels of stress hormones, lowered stress response, and alterations in DNA for a gene that regulates passage of stress hormones from mother to fetus. [More]
Researchers identify genetic variant in Latina women that protects against breast cancer

Researchers identify genetic variant in Latina women that protects against breast cancer

An international research collaboration led by UC San Francisco researchers has identified a genetic variant common in Latina women that protects against breast cancer. [More]
Whole exome sequencing can assist in early diagnosis of various disorders

Whole exome sequencing can assist in early diagnosis of various disorders

Approximately one-fourth of the 3,386 patients whose DNA was submitted for clinical whole exome testing received a diagnosis related to a known genetic disease, often ending a long search for answers for them and their parents, said researchers from the Baylor College of Medicine departments of molecular and human genetics and pediatrics and the Baylor Human Genome Sequencing Center and the University of Texas Health Science Center at Houston. [More]
Research: Ageing and depression are associated with epigenetic changes

Research: Ageing and depression are associated with epigenetic changes

Psychological stress and stress-related psychiatric disorders are associated with increased risk for aging-related diseases, but the molecular mechanisms underlying this relation are unknown. [More]
Children infected with enterovirus more likely to have type 1 diabetes

Children infected with enterovirus more likely to have type 1 diabetes

A new study published in Diabetologia (the journal of the European Association for the Study of Diabetes) shows that children who have been infected with enterovirus are 48% more likely to have developed type 1 diabetes. The study is by Dr Tsai Chung-Li, China Medical University, Taiwan, and colleagues. [More]
Females' natural resistance to bacterial pneumonia is linked to NOS3 enzyme

Females' natural resistance to bacterial pneumonia is linked to NOS3 enzyme

Researchers have linked increased resistance to bacterial pneumonia in female mice to an enzyme activated by the female sex hormone estrogen. [More]
Statistical analysis shows stage of breast cancer predicts treatment choice

Statistical analysis shows stage of breast cancer predicts treatment choice

Why did 43 percent of South Dakota women diagnosed with early-stage breast cancer surveyed choose mastectomy rather than lumpectomy? [More]
Melbourne researchers suggest new mechanism for bowel cancer development

Melbourne researchers suggest new mechanism for bowel cancer development

Melbourne researchers have challenged conventional thinking on how the bowel lining develops and, in the process, suggested a new mechanism for how bowel cancer starts. [More]