Gene

A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

What are Genes?

Deoxyribonucleic acid (DNA) is the chemical information database that carries the complete set of instructions for the cell as to the nature of the proteins produced by it, its life span, maturity, function and death. Genes are the working subunits of DNA. Each gene contains a particular set of instructions, usually coding for a particular protein or for a particular function.

Gene History

Gene Concepts

Clinical trial shows CRISPR gene editing has exciting potential to treat a rare form of blindness

A recent study published in The New England Journal of Medicine investigated the potential use of gene editing to correct a congenital retinal degeneration called CEP290 that causes early-onset vision loss.

8 May 2024

Gene linked to intellectual disability can regulate learning and memory

A gene previously linked to intellectual disability has been found to regulate learning and memory in mice.

8 May 2024

APOE4 gene linked to early onset Alzheimer's, target for therapeutic intervention

A study published in Nature Medicine delineates how APOE4 homozygosity distinctly accelerates Alzheimer's disease pathology and biomarkers from the age of 55, suggesting a unique form of the disease and a potential focus for targeted therapies.

8 May 2024

AI-driven model identifies potent cancer-killing immune cells for personalized immunotherapy

Using artificial intelligence, Ludwig Cancer Research scientists have developed a powerful predictive model for identifying the most potent cancer killing immune cells for use in cancer immunotherapies.

7 May 2024

New PET imaging agent shows promise in visualizing lesions in clear cell renal cell cancer patients

A novel investigational PET imaging agent can rapidly and accurately visualize lesions in clear cell renal cell cancer (ccRCC) patients according to new research published in the May issue of The Journal of Nuclear Medicine.

7 May 2024

Exploring associations between NMR-measured biomarkers and accelerated aging in cardiac catheterization patients

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "Associations among NMR-measured inflammatory and metabolic biomarkers and accelerated aging in cardiac catheterization patients."

7 May 2024

Unraveling the complex pathology of gastric cancer: TP53 loss and extrinsic risk factors

GC ranks as the fifth most common and fourth deadliest cancer worldwide, presenting significant health challenges, particularly in China where it is most prevalent and accounts for nearly half of newly diagnosed and death cases.

7 May 2024

New study highlights sharp rise in exposures to synthetic cannabis products among youth

A sharp rise in exposures to synthetic cannabis products among youth -; some leading to hospitalization -; highlights the need for increased education around the dangers of exposure and increased focus on safe storage and packaging, according to pediatricians and researchers at Nationwide Children's Hospital and the Central Ohio Poison Center.

7 May 2024

Broken String Biosciences and the Francis Crick Institute collaborate to advance ALS research

Partnership to expand applications of DNA break-mapping technology and advance understanding of genomic instability in development of the neurodegenerative disease amyotrophic lateral sclerosis.

From Broken String Biosciences 7 May 2024

Vitamin D receptor polymorphism found to influence COVID-19 severity

Researchers compared SNPs in the vitamin D receptor (VDR) gene between mild and severe COVID-19 patients.

7 May 2024

Neural circuits revealed as key regulators in body's immune response, study finds

A recent study in Nature reveals how specific neural circuits within the body-brain axis regulate immune responses, highlighting potential new therapeutic approaches for immune disorders.

6 May 2024

Rutgers scientists create CRISPR-edited mice to study the neurobiology of Tourette disorder

In research that may be a step forward toward finding personalized treatments for Tourette disorder, scientists at Rutgers University–New Brunswick have bred mice that exhibit some of the same behaviors and brain abnormalities seen in humans with the disorder.

6 May 2024

CRISPR-based gene editing shows promise in treating rare form of blindness

About 79% of clinical trial participants experienced measurable improvement after receiving experimental, CRISPR-based gene editing that is designed to fix a rare form of blindness, according to a paper published in the New England Journal of Medicine.

6 May 2024

MedStar Washington Hospital Center enrolls first U.S. patient in gene-editing therapy trial for heart disease

The first U.S. heart patient involved in a study for a new gene-editing therapy directly infused inside the body has successfully been enrolled at MedStar Washington Hospital Center.

6 May 2024

CRISPR gene editing shows promise for treating individuals with a form of inherited blindness

Results from a groundbreaking clinical trial of CRISPR gene editing in 14 individuals with a form of inherited blindness show that the treatment is safe and led to measurable improvements in 11 of the participants treated.

6 May 2024

Study identifies APOE4 homozygotes as high-risk group for Alzheimer's disease

Researchers from the Research Area on Neurological Diseases, Neuroscience, and Mental Health at the Sant Pau Research Institute, led by Dr. Juan Fortea, Director of the Memory Unit of the Neurology Service at the same hospital, have found that over 95% of individuals over 65 years old who have two copies of the APOE4 gene -APOE4 homozygotes- show biological characteristics of Alzheimer's pathology in the brain or biomarkers of this disease in cerebrospinal fluid and PET scans.

6 May 2024

Lab to plant: Scaling up API processes with Dr. James Mencel's guidance

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Gene

Overview

Gene History

Gene Concepts

Latest Gene News and Research

Clinical trial shows CRISPR gene editing has exciting potential to treat a rare form of blindness

Gene linked to intellectual disability can regulate learning and memory

APOE4 gene linked to early onset Alzheimer's, target for therapeutic intervention

AI-driven model identifies potent cancer-killing immune cells for personalized immunotherapy

New PET imaging agent shows promise in visualizing lesions in clear cell renal cell cancer patients

Exploring associations between NMR-measured biomarkers and accelerated aging in cardiac catheterization patients

Unraveling the complex pathology of gastric cancer: TP53 loss and extrinsic risk factors

New study highlights sharp rise in exposures to synthetic cannabis products among youth

Broken String Biosciences and the Francis Crick Institute collaborate to advance ALS research

Vitamin D receptor polymorphism found to influence COVID-19 severity

Neural circuits revealed as key regulators in body's immune response, study finds

Rutgers scientists create CRISPR-edited mice to study the neurobiology of Tourette disorder

CRISPR-based gene editing shows promise in treating rare form of blindness

MedStar Washington Hospital Center enrolls first U.S. patient in gene-editing therapy trial for heart disease

CRISPR gene editing shows promise for treating individuals with a form of inherited blindness

Study identifies APOE4 homozygotes as high-risk group for Alzheimer's disease

Lab to plant: Scaling up API processes with Dr. James Mencel's guidance

Researchers review current evidence on Candida auris, an emerging multidrug-resistant yeast

Durable lymph-node expansion improves vaccine responses against tumors

NK cells' role in cancer therapy resistance unveiled

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut