Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Genetic signature may help predict disease-free survival in patients with non-small cell lung cancer

A new study identified a set of 140 genes that may help predict enhanced disease-free survival in patients with non-small cell lung cancer (NSCLC) treated with a combination of immunotherapy and low-dose radiation.

23 Feb 2024

Advancing gene regulatory network inference with causal discovery and graph neural networks

Gene regulatory networks (GRNs) depict the regulatory mechanisms of genes within cellular systems as a network, offering vital insights for understanding cell processes and molecular interactions that determine cellular phenotypes.

23 Feb 2024

New study defines clinical phenotype of Post-infectious ME/CFS, highlighting unique biomarker insights

The pathophysiological mechanisms of PI myalgic encephalitis/chronic fatigue syndrome (ME/CFS).

23 Feb 2024

Females' immune system edges out males but at a cost of higher autoimmune risk

A review article highlights how two X chromosomes in females influence immune system composition and function, leading to faster infection clearance and stronger vaccination responses but also a higher risk of autoimmune diseases.

22 Feb 2024

Study reveals unexpected link between cell membrane damage and cellular senescence

Our cells are surrounded by a fragile membrane that's only 5 nanometers thick, 1/20 of a soap bubble. Cells are easily damaged by physiological activities, including muscle contraction and tissue injury.

22 Feb 2024

Chan Zuckerberg Initiative funds Notre Dame research on aging and neurodegeneration

The University of Notre Dame has received a Collaborative Pairs Pilot Project Award from the Chan Zuckerberg Initiative to study genes that affect neurodegenerative diseases, such as Alzheimer's disease.

21 Feb 2024

Study reveals mechanism of drug targeting protein modification in tumor suppressor genes

Researchers have revealed the mechanism of a drug shown to be effective in treating certain types of cancer, which targets a protein modification silencing the expression of multiple tumor suppressor genes.

21 Feb 2024

Unlocking non-hormonal male contraception with HDAC inhibitors

Surveys show most men in the United States are interested in using male contraceptives, yet their options remain limited to unreliable condoms or invasive vasectomies.

20 Feb 2024

Finasteride may offer life-saving benefits beyond hair loss treatment

The drug finasteride, also known as Propecia or Proscar, treats male pattern baldness and enlarged prostate in millions of men worldwide.

20 Feb 2024

Breakthrough gene therapy method utilizes bird retrotransposon for safe gene insertion

The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease.

20 Feb 2024

Study uncovers key genes and cell types that may affect pathogenesis of primary open-angle glaucoma

Although primary open-angle glaucoma (POAG) is the leading cause of blindness in people over the age of 55, there remains no cure for the disease and its biological mechanisms are not well understood.

16 Feb 2024

New DNA recombination toolbox surpasses CRISPR for genome engineering

Belgian researchers from VIB-KU Leuven Center for Microbiology and VIB-UGent Center for Plant Systems Biology have developed a new toolbox of 16 different short DNA sequences that allow triggering controlled and specific recombination events in any genome.

16 Feb 2024

Novel splicing mechanism for short introns discovered

Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been uncovered.

15 Feb 2024

Researchers discover new mechanism of action between the nutrient adaptation of intestinal stem cells and aging

Researchers used an organ-wide approach to quantitatively analyze cell number, size, and identity regulation upon nutrient-induced tissue adaptation of the Drosophila midgut.

15 Feb 2024

Combo of targeted and immunotherapy may boost NSCLC treatment by overcoming immune resistance and enhancing anti-tumor activity

Researchers evaluated rational combination treatment regimens for advanced/metastatic non-small-cell lung cancer (NSCLC).

15 Feb 2024

Gene Expression News and Research

Further Reading

Genetic signature may help predict disease-free survival in patients with non-small cell lung cancer

Advancing gene regulatory network inference with causal discovery and graph neural networks

New study defines clinical phenotype of Post-infectious ME/CFS, highlighting unique biomarker insights

Females' immune system edges out males but at a cost of higher autoimmune risk

Study reveals unexpected link between cell membrane damage and cellular senescence

Chan Zuckerberg Initiative funds Notre Dame research on aging and neurodegeneration

Study reveals mechanism of drug targeting protein modification in tumor suppressor genes

Unlocking non-hormonal male contraception with HDAC inhibitors

Finasteride may offer life-saving benefits beyond hair loss treatment

Breakthrough gene therapy method utilizes bird retrotransposon for safe gene insertion

Study uncovers key genes and cell types that may affect pathogenesis of primary open-angle glaucoma

New DNA recombination toolbox surpasses CRISPR for genome engineering

Novel splicing mechanism for short introns discovered

Researchers discover new mechanism of action between the nutrient adaptation of intestinal stem cells and aging

Combo of targeted and immunotherapy may boost NSCLC treatment by overcoming immune resistance and enhancing anti-tumor activity

Oral bacteria interaction leads to smelly breath

New breakthrough in pancreatic cancer research could help slow the disease's deadly spread

Researchers develop groundbreaking technique to detect chemoresistance using ultrasound

Gene editing gets a boost with new CRISPR-COPIES

Study reveals a crucial survival tactic employed by cancer cells

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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