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RBFox2 protein plays critical role in heart failure

RBFox2 protein plays critical role in heart failure

Researchers at the University of California, San Diego School of Medicine have identified a key piece in the complex molecular puzzle underlying heart failure - a serious and sometimes life-threatening disorder affecting more than 5 million Americans. [More]
Researchers one step closer to unraveling complex processes crucial to sperm development

Researchers one step closer to unraveling complex processes crucial to sperm development

Researchers are one step closer to unraveling the extraordinarily complex series of processes that leads to an event crucial to human reproduction: the creation of sperm. [More]
UIC researchers identify genetic variation that increases MS risk in women

UIC researchers identify genetic variation that increases MS risk in women

Researchers at the University of Illinois at Chicago have identified a genetic variation that in women significantly increases their risk of developing multiple sclerosis. [More]
New cell powerhouse sequencing technique may provide clearer picture of inherited disease risk

New cell powerhouse sequencing technique may provide clearer picture of inherited disease risk

A new sequencing technique may provide a clearer picture of how genes in mitochondria, the "powerhouses" that turn sugar into energy in human cells, shape each person's inherited risk for diabetes, heart disease and cancer, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published online this week in the journal Nucleic Acids Research. [More]
Study shows how mutations that cause Alzheimer's disease lead to neurodegeneration, dementia

Study shows how mutations that cause Alzheimer's disease lead to neurodegeneration, dementia

A study from researchers at Massachusetts General Hospital and Brigham and Women's Hospital reveals for the first time exactly how mutations associated with the most common form of inherited Alzheimer's disease produce the disorder's devastating effects. [More]
Finding may help advance experimental approach to improving public health

Finding may help advance experimental approach to improving public health

Scientists have discovered a new way to manipulate how cells function, a finding that might help advance an experimental approach to improving public health: DNA vaccines, which could be more efficient, less expensive and easier to store than traditional vaccines. [More]
GeneSight test better predicts antidepressant outcomes for patients with depression

GeneSight test better predicts antidepressant outcomes for patients with depression

The combinatorial, multi-gene GeneSight test has been found to better predict antidepressant treatment outcomes for patients with depression, and their use of health care resources, than any of the individual genes that comprise the test, according to a peer-reviewed analysis by investigators from the Mayo Clinic and Assurex Health, and published online by The Pharmacogenomics Journal. [More]
Resverlogix, Emerald Logic complete collaborative research program

Resverlogix, Emerald Logic complete collaborative research program

Resverlogix Corp. today announced that it has completed a collaborative research program with Emerald Logic, a leader in quantitative analytics. Using Fast Collective Evolution Technology (FACET), Emerald Logic analyzed Resverlogix's complete clinical dataset including all measurements obtained from each of 798 patients who participated in the Company's Phase 2 clinical trials ASSERT, SUSTAIN and ASSURE. [More]
Changing breast cancer cells' shape could make the disease more sensitive to treatments

Changing breast cancer cells' shape could make the disease more sensitive to treatments

Changing the shape of breast cancer cells could make the disease more sensitive to treatments - even driving the body's own inflammatory response against a tumour - a new study shows. [More]
Environmental conditions play significant role in determining growth, height

Environmental conditions play significant role in determining growth, height

If you've ever wondered why you aren't a little taller, it turns out it's not all about genetics. In findings published in the Journal of Pediatrics (January 2015), an Israeli research team shows that the environment in which one lives from the womb to about age one largely determines an adult's height. [More]
Kansas State researchers preparing for next potential influenza strain

Kansas State researchers preparing for next potential influenza strain

As seasonal influenza cases decrease across the United States, Kansas State University researchers are preparing for the next potential virulent strain of flu. [More]
UCLA life scientists develop new method to find genetic markers for many diseases

UCLA life scientists develop new method to find genetic markers for many diseases

UCLA life scientists have created an accurate new method to identify genetic markers for many diseases -- a significant step toward a new era of personalized medicine, tailored to each person's DNA and RNA. [More]
CHOPS syndrome sheds light on key biological processes during human development

CHOPS syndrome sheds light on key biological processes during human development

Analyzing a puzzling multisystem disorder in three children, genetic experts have identified a new syndrome, shedding light on key biological processes during human development. The research also provides important information to help caregivers manage the disorder, and may offer clues to eventually treating it. [More]
MIT researchers develop new nanodevice that can help overcome drug resistance

MIT researchers develop new nanodevice that can help overcome drug resistance

Chemotherapy often shrinks tumors at first, but as cancer cells become resistant to drug treatment, tumors can grow back. A new nanodevice developed by MIT researchers can help overcome that by first blocking the gene that confers drug resistance, then launching a new chemotherapy attack against the disarmed tumors. [More]
BUSM researchers discover genes involved in formation of lung tumors

BUSM researchers discover genes involved in formation of lung tumors

The lung transcription factor Nkx2-1 is an important gene regulating lung formation and normal respiratory functions after birth. Alterations in the expression of this transcription factor can lead to diseases such as lung interstitial disease, post-natal respiratory distress and lung cancer. [More]
Caltech researchers reveal new information that could help fight against hookworms

Caltech researchers reveal new information that could help fight against hookworms

Tiny parasitic hookworms infect nearly half a billion people worldwide--almost exclusively in developing countries--causing health problems ranging from gastrointestinal issues to cognitive impairment and stunted growth in children. By sequencing and analyzing the genome of one particular hookworm species, Caltech researchers have uncovered new information that could aid the fight against these parasites. [More]
Autism Speaks' affiliate DELSIA announces new funding for clinical trial of cognitive video game

Autism Speaks' affiliate DELSIA announces new funding for clinical trial of cognitive video game

Autism Speaks' not-for-profit affiliate Delivering Scientific Innovation for Autism has announced new funding for clinical testing of a cognitive video game designed to improve executive function skills in children and adolescents with autism. [More]
Scientists sequence genome of hookworm

Scientists sequence genome of hookworm

In an advance that may potentially lead to new treatments for parasitic hookworms, scientists at the University of Massachusetts Medical School and Cornell University have sequenced the genome of the hookworm, Ancylostoma ceylanicum. [More]
New genetic discovery may lead to effective treatments for Huntington's disease

New genetic discovery may lead to effective treatments for Huntington's disease

A new genetic discovery in the field of Huntington's disease (HD) could mean a more effective way in determining severity of this neurological disease when using specific treatments. This study may provide insight for treatments that would be effective in slowing down or postponing the death of neurons for people who carry the HD gene mutation, but who do not yet show symptoms of the disease. [More]
Study details a new pathway for tumor formation

Study details a new pathway for tumor formation

Researchers at the University of Wisconsin-Madison School of Veterinary Medicine (SVM) have identified the biological mechanism that may give some cancer cells the ability to form tumors in dogs. [More]