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Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior

Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior

Two recently discovered genetic differences between brain cancer cells and normal tissue cells -- an altered gene and a snippet of noncoding genetic material -- could offer clues to tumor behavior and potential new targets for therapy, Johns Hopkins scientists report. [More]
Cornell researchers develop chemical probe activated by UV light to control inflammation

Cornell researchers develop chemical probe activated by UV light to control inflammation

Black light does more than make posters glow. Cornell researchers have developed a chemical tool to control inflammation that is activated by ultraviolet (UV) light. [More]
Combination of demineralized bone and gene therapy shows promise for treating pseudarthrosis

Combination of demineralized bone and gene therapy shows promise for treating pseudarthrosis

A team headed by Professor Albert Rizvanov, director of the Gene and Cell Technologies Open Lab, created a gene therapy drug that encodes growth factors for the stimulation of blood vessel and bone formation. [More]
Scientists devise new radiation-free probe for imaging molecules in the brain

Scientists devise new radiation-free probe for imaging molecules in the brain

Scientists hoping to get a glimpse of molecules that control brain activity have devised a new probe that allows them to image these molecules without using any chemical or radioactive labels. [More]
Scientists discover unique genomic changes integral to testicular cancer development

Scientists discover unique genomic changes integral to testicular cancer development

Researchers led by scientists at Dana-Farber Cancer Institute say they have identified unique genomic changes that may be integral to testicular cancer development and explain why the great majority are highly curable with chemotherapy - unlike most solid tumors. [More]
Scientists discover molecular link between rare childhood genetic disease and major cancer gene

Scientists discover molecular link between rare childhood genetic disease and major cancer gene

A team of researchers led by a University of Rhode Island scientist has discovered an important molecular link between a rare childhood genetic disease, Fanconi anemia, and a major cancer gene called PTEN. [More]
Nature Methods publishes comparative study of leading Protein-Protein Interaction Networks

Nature Methods publishes comparative study of leading Protein-Protein Interaction Networks

Nature Methods published (online) a comparative study of leading Protein-Protein Interaction (PPI) Networks. [More]
Researchers uncover new prognostic marker and possible therapeutic target for Ewing's sarcoma

Researchers uncover new prognostic marker and possible therapeutic target for Ewing's sarcoma

Researchers of the Sarcoma research group of the Bellvitge Biomedical Research Institute, led by Dr. Òscar Martínez-Tirado, have first described the methylation profile of Ewing's sarcoma, a cancer of bone and soft tissues that mainly affects children and teenagers. [More]
New global network to explore link between genes and environmental factors to tackle health challenges

New global network to explore link between genes and environmental factors to tackle health challenges

A new global network linking leading research centres across the world has launched today to tackle some of the most pressing global health challenges of our time such as autism, cancer, diabetes and dementia. [More]
PCSK9 and HMGCR genetic variations that lower bad cholesterol affect risk of cardiovascular events

PCSK9 and HMGCR genetic variations that lower bad cholesterol affect risk of cardiovascular events

In a new study published in the December 1, 2016 issue of The New England Journal of Medicine, researchers at Brigham and Women's Hospital, and a collaboration of international researchers, studied variants in the genes encoding HMGCR and PCSK9 that affect cholesterol levels, and found that variants that lowered LDL (or "bad") cholesterol in each gene were associated with nearly identical protective effects on the risk of cardiovascular events per unit reduction in LDL cholesterol. [More]
Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

The Allen Institute for Cell Science has released the Allen Cell Collection: the first publicly available collection of gene edited, fluorescently tagged human induced pluripotent stem cells that target key cellular structures with unprecedented clarity. [More]
Scientists identify microrna that provides clues for quieting auditory hallucinations of schizophrenia

Scientists identify microrna that provides clues for quieting auditory hallucinations of schizophrenia

St. Jude Children's Research Hospital scientists have identified a small RNA (microRNA) that may be essential to restoring normal function in a brain circuit associated with the "voices" and other hallucinations of schizophrenia. [More]
Discovery of four genes linked to fatal aneurysms could provide potential target for treatments

Discovery of four genes linked to fatal aneurysms could provide potential target for treatments

Thousands of lives could be saved every year after it was discovered a fatal cardiovascular condition could be linked to four genes, research has found. [More]
Dirt beneath New York City may provide new weapons to fight against disease

Dirt beneath New York City may provide new weapons to fight against disease

Microbes have long been an invaluable source of new drugs. And to find more, we may have to look no further than the ground beneath our feet. [More]
Scientists develop safe, highly efficient method to improve searching of new germicides

Scientists develop safe, highly efficient method to improve searching of new germicides

Scientists from the Lomonosov Moscow State University in cooperation with colleagues have worked out a safe, not that expensive and highly efficient method, which allows to speed up and improve searching of new germicides. [More]
Early life history and genetics may play crucial role in shaping gut microbiome

Early life history and genetics may play crucial role in shaping gut microbiome

Genetics and birthplace have a big effect on the make-up of the microbial community in the gut, according to research published Nov. 28. in the journal Nature Microbiology. [More]
Scientists develop easy-to-use software tool to detect important genetic mutations

Scientists develop easy-to-use software tool to detect important genetic mutations

Scientists have developed an easy-to-use software tool that can detect important genetic mutations that previously needed to be identified by a separate test. [More]
DNA changes in blood samples could pave way for simple tests to diagnose IBD

DNA changes in blood samples could pave way for simple tests to diagnose IBD

Scientists have identified chemical changes in the DNA of patients with inflammatory bowel diseases that could improve screening for the conditions. [More]
Editing preferences of enzymes may play role in infertility and cancer

Editing preferences of enzymes may play role in infertility and cancer

To "turn off" particular regions of genes or protect them from damage, DNA strands can wrap around small proteins, called histones, keeping out all but the most specialized molecular machinery. [More]
Gene mutation appears to increase risk of Parkinson's disease in Caucasians

Gene mutation appears to increase risk of Parkinson's disease in Caucasians

A defect in a gene that produces dopamine in the brain appears to accelerate the onset of Parkinson's disease, according to new research from Iowa State University. The effect is particularly dramatic for people under age 50. [More]
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