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Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

A study in The Journal of Cell Biology by scientists at the University of Massachusetts Medical School reveals important new details about the inner workings of the CRISPR-Cas9 machinery in live cells that may have implications for the development of therapeutics that use the powerful gene editing tool. [More]
Researchers find better way to purify liver cells made from induced pluripotent stem cells

Researchers find better way to purify liver cells made from induced pluripotent stem cells

A research team including developmental biologist Stephen A. Duncan, D. Phil., SmartState Chair of Regenerative Medicine at the Medical University of South Carolina, has found a better way to purify liver cells made from induced pluripotent stem cells (iPSCs). [More]
Penn scientists find striking similarities between human patients with LCA and dogs

Penn scientists find striking similarities between human patients with LCA and dogs

Ciliopathies are diseases that affect the cilia, sensory organelles that most mammalian cells possess and which play a critical role in many biological functions. [More]
Scripps collaborates with MD Anderson for clinically integrated cancer care program

Scripps collaborates with MD Anderson for clinically integrated cancer care program

Scripps Health and The University of Texas MD Anderson Cancer Center have reached a partnership agreement to create Scripps MD Anderson Cancer Center, a comprehensive and clinically integrated cancer care program in San Diego that will provide adult cancer patients greater access to the most advanced oncology care available throughout Southern California. [More]
Nicotinic receptors could be new therapeutic target to prevent memory loss linked to Alzheimer's

Nicotinic receptors could be new therapeutic target to prevent memory loss linked to Alzheimer's

Several scientific studies have indicated that nicotine may be beneficial for memory function. [More]
Fluid-filled sacs that brain cells make to trap amyloid may contribute to Alzheimer's disease

Fluid-filled sacs that brain cells make to trap amyloid may contribute to Alzheimer's disease

Vesicles, fluid-filled sacs that brain cells make to trap amyloid, a hallmark of Alzheimer's, appear to also contribute to the disease, scientists report. [More]
Long-term exposure to combination of lower LDL-C and SBP can reduce cardiovascular risk

Long-term exposure to combination of lower LDL-C and SBP can reduce cardiovascular risk

Long-term exposure to the combination of even modestly lower LDL cholesterol (LDL-C) and systolic blood pressure (SBP) has the potential to "dramatically reduce" a person's lifetime risk of cardiovascular disease, according to new findings reported at ESC Congress 2016. [More]
Boehringer Ingelheim and Duke expand collaboration to create largest patient registry for idiopathic pulmonary fibrosis (IPF)

Boehringer Ingelheim and Duke expand collaboration to create largest patient registry for idiopathic pulmonary fibrosis (IPF)

Boehringer Ingelheim Pharmaceuticals, Inc. and the Duke Clinical Research Institute (DCRI) announced today the expansion of the Idiopathic Pulmonary Fibrosis – PROspective Outcomes (IPF-PRO) Registry, a patient registry developed to uncover insights into IPF, a rare and serious lung disease. The expansion will increase the study enrollment from 300 patients at 18 study sites to 1,500 patients at approximately 45 sites, creating the largest registry of newly diagnosed IPF patients. [More]
Mediterranean Diet linked to mortality risk reduction in patients with cardiovascular disease

Mediterranean Diet linked to mortality risk reduction in patients with cardiovascular disease

The Mediterranean diet is associated with a reduced risk of death in patients with a history of cardiovascular disease, according to results from the observational Moli-sani study presented at ESC Congress 2016 today. [More]
Skin cells derived from autistic donors grow faster than those from control subjects

Skin cells derived from autistic donors grow faster than those from control subjects

Brain cells grow faster in children with some forms of autism due to distinct changes in core cell signaling patterns, according to research from the laboratory of Anthony Wynshaw-Boris, MD, PhD, chair of the department of genetics and genome sciences at Case Western Reserve University School of Medicine. [More]
NanoScope awarded AGI Grant to re-sensitize photo-degenerated retinal areas with MCO

NanoScope awarded AGI Grant to re-sensitize photo-degenerated retinal areas with MCO

Millions of individuals affected by Retinitis Pigmentosa (RP) are visually impaired due to photo-degeneration of retina. The visual loss starts with the peripheral region progressing towards the center leading to tunnel vision. Currently, there is no cure to restore vision in these patients. The disease leads not only to physical impairment, but has a significant emotional and psychological impact on quality of life of patients as well as their family members. [More]
Newly-developed epigenetic test can be used to identify tumors responsible for metastasis in cancer patient

Newly-developed epigenetic test can be used to identify tumors responsible for metastasis in cancer patient

In patients with cancer, initial diagnosis most often includes the detection of the primary or original tumor and the presence or absence of metastases, ie cells from the original tumor that have escaped from their original location and are growing into other tissues of the patient. [More]
QOL Medical to introduce new disease awareness-raising tool at WCPGHAN 2016

QOL Medical to introduce new disease awareness-raising tool at WCPGHAN 2016

QOL Medical, LLC announced today they will introduce a ground breaking hyper-targeted marketing tool at the 5th Annual World Congress of Pediatric Gastroenterology, Hepatology and Nutrition, from October 5th-8th 2016 in Montreal, Canada. [More]
Basic cell biology research into neurodegeneration may fuel understanding of neurodegenerative diseases

Basic cell biology research into neurodegeneration may fuel understanding of neurodegenerative diseases

Clinical trials and translational medicine have certainly given people hope and rapid pathways to cures for some of mankind's most troublesome diseases, but now is not the time to overlook the power of basic research, says UC Santa Barbara neuroscientist Kenneth S. Kosik. [More]
Researchers explore molecular mechanisms through which lead exposure may affect neural stem cells

Researchers explore molecular mechanisms through which lead exposure may affect neural stem cells

Researchers have identified a potential molecular mechanism through which lead, a pervasive environmental toxin, may harm neural stem cells and neurodevelopment in children. [More]
Researchers find new way for early prediction of leukemic relapse

Researchers find new way for early prediction of leukemic relapse

Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a particularly problematic disease that typically afflicts older patients who have often already experienced a bout with cancer. [More]
SSRI treatment improves cognitive and social functioning in young children with fragile X

SSRI treatment improves cognitive and social functioning in young children with fragile X

Treatment with sertraline may provide nominal but important improvements in cognition and social participation in very young children with fragile X syndrome, the most common genetic cause of intellectual disability and the leading single-gene cause of autism, a study by researchers with the UC Davis MIND Institute has found. [More]
Kobe University researchers develop new technique for high-level genome editing operation

Kobe University researchers develop new technique for high-level genome editing operation

A team involving Kobe University researchers has succeeded in developing 'Target-AID', a genome editing technique that does not cleave the DNA. [More]
Naturally-occurring sugars in woman's breast milk may protect infants against life threatening bacteria

Naturally-occurring sugars in woman's breast milk may protect infants against life threatening bacteria

A type of sugar found naturally in some women's breast milk may protect newborn babies from infection with a potentially life threatening bacterium called Group B streptococcus, according to a new study from Imperial College London. [More]
Chromatrap develops new range of optimised ChIP assay kits for genetic research

Chromatrap develops new range of optimised ChIP assay kits for genetic research

Chromatrap is a pioneer in the development of solid-state filter-based technology that significantly enhances and accelerates the important epigenetic research tool of chromatin immunoprecipitation (ChIP). [More]
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