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Researchers discover retina protein crucial for vision

Researchers discover retina protein crucial for vision

Research led by Nicolas Bazan, MD, PhD, Boyd Professor and Director of the LSU Health New Orleans Neuroscience Center of Excellence, discovered a protein in the retina that is crucial for vision. The paper reports, for the first time, the key molecular mechanisms leading to visual degeneration and blindness. [More]
Finding may help advance experimental approach to improving public health

Finding may help advance experimental approach to improving public health

Scientists have discovered a new way to manipulate how cells function, a finding that might help advance an experimental approach to improving public health: DNA vaccines, which could be more efficient, less expensive and easier to store than traditional vaccines. [More]
GeneSight test better predicts antidepressant outcomes for patients with depression

GeneSight test better predicts antidepressant outcomes for patients with depression

The combinatorial, multi-gene GeneSight test has been found to better predict antidepressant treatment outcomes for patients with depression, and their use of health care resources, than any of the individual genes that comprise the test, according to a peer-reviewed analysis by investigators from the Mayo Clinic and Assurex Health, and published online by The Pharmacogenomics Journal. [More]
Changing breast cancer cells' shape could make the disease more sensitive to treatments

Changing breast cancer cells' shape could make the disease more sensitive to treatments

Changing the shape of breast cancer cells could make the disease more sensitive to treatments - even driving the body's own inflammatory response against a tumour - a new study shows. [More]
Environmental conditions play significant role in determining growth, height

Environmental conditions play significant role in determining growth, height

If you've ever wondered why you aren't a little taller, it turns out it's not all about genetics. In findings published in the Journal of Pediatrics (January 2015), an Israeli research team shows that the environment in which one lives from the womb to about age one largely determines an adult's height. [More]
New study shows who benefits most from statin therapy

New study shows who benefits most from statin therapy

Research has demonstrated that the risk for developing coronary heart disease depends on a host of risk factors that are related both to lifestyle and genetics. In a new study from Brigham and Women's Hospital, Washington University School of Medicine in St. Louis, and Massachusetts General Hospital, researchers tested whether a composite of genetic variants could identify the risk of cardiovascular death and heart attacks as well as identify individuals who derived greater clinical benefit from statin therapy. [More]
UCLA life scientists develop new method to find genetic markers for many diseases

UCLA life scientists develop new method to find genetic markers for many diseases

UCLA life scientists have created an accurate new method to identify genetic markers for many diseases -- a significant step toward a new era of personalized medicine, tailored to each person's DNA and RNA. [More]
Study on spider venom may lead to new class of potent painkillers

Study on spider venom may lead to new class of potent painkillers

New research shows that seven compounds of the countless found in spider venom block a key step in the body's ability to pass pain signals to the brain. The hunt for a medicine based on just one of these compounds, which would open up a new class of potent painkillers, is now a step closer according to new research published in the British Journal of Pharmacology. [More]
Study: Family Based Interpersonal Psychotherapy effective in treating preadolescents with depression

Study: Family Based Interpersonal Psychotherapy effective in treating preadolescents with depression

A recent study published in the March 2015 issue of the Journal of the American Academy of Child and Adolescent Psychiatry finds that Family Based Interpersonal Psychotherapy (FB-IPT) is more effective in treating preadolescent children with depression compared to child-centered therapy (CCT). [More]
MD Anderson scientists show why some brain cancer patients develop resistance to treatments

MD Anderson scientists show why some brain cancer patients develop resistance to treatments

Scientists at The University of Texas MD Anderson Cancer Center may have discovered why some brain cancer patients develop resistance to standard treatments including radiation and the chemotherapy agent temozolomide. [More]
Investigational drug may attack cause of vaso-occlusion crises in sickle cell anemia

Investigational drug may attack cause of vaso-occlusion crises in sickle cell anemia

Treatment for painful episodes of blood vessel obstruction in sickle cell anemia is currently limited to controlling pain, but an investigational therapy might be able to interfere with the underlying cause of these events, known as vaso-occlusion crises, researchers at Duke Medicine report. [More]
Scientists find gorilla origins in two human AIDS virus lineages

Scientists find gorilla origins in two human AIDS virus lineages

Two of the four known groups of human AIDS viruses (HIV-1 groups O and P) have originated in western lowland gorillas, according to an international team of scientists from the Perelman School of Medicine at the University of Pennsylvania, the University of Montpellier, the University of Edinburgh, and others. [More]
CHOPS syndrome sheds light on key biological processes during human development

CHOPS syndrome sheds light on key biological processes during human development

Analyzing a puzzling multisystem disorder in three children, genetic experts have identified a new syndrome, shedding light on key biological processes during human development. The research also provides important information to help caregivers manage the disorder, and may offer clues to eventually treating it. [More]
MIT researchers develop new nanodevice that can help overcome drug resistance

MIT researchers develop new nanodevice that can help overcome drug resistance

Chemotherapy often shrinks tumors at first, but as cancer cells become resistant to drug treatment, tumors can grow back. A new nanodevice developed by MIT researchers can help overcome that by first blocking the gene that confers drug resistance, then launching a new chemotherapy attack against the disarmed tumors. [More]
Caltech researchers reveal new information that could help fight against hookworms

Caltech researchers reveal new information that could help fight against hookworms

Tiny parasitic hookworms infect nearly half a billion people worldwide--almost exclusively in developing countries--causing health problems ranging from gastrointestinal issues to cognitive impairment and stunted growth in children. By sequencing and analyzing the genome of one particular hookworm species, Caltech researchers have uncovered new information that could aid the fight against these parasites. [More]
Experts review diagnostic approaches to treat obstructive coronary artery disease in women

Experts review diagnostic approaches to treat obstructive coronary artery disease in women

Obstructive coronary artery disease (CAD) in women often presents with different types of symptoms than in men and can be challenging to diagnose due to a variety of factors. A national panel of experts convened to review the latest evidence regarding CAD in women, diagnostic approaches, and new types of tests and technologies. [More]
Data provides better understanding of genetic activity during lung cancer development

Data provides better understanding of genetic activity during lung cancer development

Scientists at the University of Granada, incollaboration with the universities of Harvard and Yale (United States) have provided new data for a better understanding of the alterations produced during the development of lung cancer, the tumour with the highest yearly death rate in Spain. [More]
EMA's CHMP backs JINARC (tolvaptan) for autosomal dominant polycystic kidney disease

EMA's CHMP backs JINARC (tolvaptan) for autosomal dominant polycystic kidney disease

Otsuka Pharmaceutical Co., Ltd. announced today that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency has recommended JINARC (tolvaptan) for approval. [More]
Alizé Pharma announces launch of AZP-531 Phase II trial in patients with Prader-Willi syndrome

Alizé Pharma announces launch of AZP-531 Phase II trial in patients with Prader-Willi syndrome

Alizé Pharma, a company specialized in the development of drugs for the treatment of metabolic disorders and rare diseases, today announces the launch of a Phase II clinical trial of AZP-531, its unacylated ghrelin analog, in patients with Prader-Willi syndrome. [More]
New genetic discovery may lead to effective treatments for Huntington's disease

New genetic discovery may lead to effective treatments for Huntington's disease

A new genetic discovery in the field of Huntington's disease (HD) could mean a more effective way in determining severity of this neurological disease when using specific treatments. This study may provide insight for treatments that would be effective in slowing down or postponing the death of neurons for people who carry the HD gene mutation, but who do not yet show symptoms of the disease. [More]