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Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior

Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior

Two recently discovered genetic differences between brain cancer cells and normal tissue cells -- an altered gene and a snippet of noncoding genetic material -- could offer clues to tumor behavior and potential new targets for therapy, Johns Hopkins scientists report. [More]
Combination of demineralized bone and gene therapy shows promise for treating pseudarthrosis

Combination of demineralized bone and gene therapy shows promise for treating pseudarthrosis

A team headed by Professor Albert Rizvanov, director of the Gene and Cell Technologies Open Lab, created a gene therapy drug that encodes growth factors for the stimulation of blood vessel and bone formation. [More]
Newcastle scientists develop promising new test to identify patients with rare liver disease

Newcastle scientists develop promising new test to identify patients with rare liver disease

Newcastle scientists and medics have developed a promising new test to identify patients with a rare liver disease who will not respond to standard treatment, allowing earlier intervention with alternatives. [More]
Researchers receive Stafford Fox Medical Research Foundation grant to accelerate CFS diagnosis

Researchers receive Stafford Fox Medical Research Foundation grant to accelerate CFS diagnosis

Major improvement in the diagnosis of Chronic Fatigue Syndrome is expected following the award of $4m in funding to one of Australia’s foremost authorities on the condition. [More]
Elucigene collaborates with Congenica to develop new NGS kit for cystic fibrosis

Elucigene collaborates with Congenica to develop new NGS kit for cystic fibrosis

The emergence of new therapies that treat the causes of cystic fibrosis are creating an imperative for more accurate variant analysis. [More]
Reseachers identify cellular ‘off’ switch for inflammatory immune response in asthma attacks

Reseachers identify cellular ‘off’ switch for inflammatory immune response in asthma attacks

Working with human immune cells in the laboratory, Johns Hopkins researchers report they have identified a critical cellular "off" switch for the inflammatory immune response that contributes to lung-constricting asthma attacks. [More]
Cigarette smoking may lead to fibrosis in the heart and kidneys, study reveals

Cigarette smoking may lead to fibrosis in the heart and kidneys, study reveals

Smoking may lead to fibrosis in the heart and kidneys and can worsen existing kidney disease, according to a new study. [More]
Scientists discover molecular link between rare childhood genetic disease and major cancer gene

Scientists discover molecular link between rare childhood genetic disease and major cancer gene

A team of researchers led by a University of Rhode Island scientist has discovered an important molecular link between a rare childhood genetic disease, Fanconi anemia, and a major cancer gene called PTEN. [More]
Protective barrier inside chromosomes helps prevent errors during cell division, study finds

Protective barrier inside chromosomes helps prevent errors during cell division, study finds

Fresh insights into the structures that contain our genetic material could explain how the body's cells stay healthy. [More]
Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

Researchers at NEOMED have just identified a major connection between areas of the brainstem - the ancient area that controls mood, sleep and metabolism - and detrimental changes to bone in a preclinical model of Alzheimer's disease (AD). [More]
Type 2 diabetes linked to long list of complications that can affect health and quality of life

Type 2 diabetes linked to long list of complications that can affect health and quality of life

T2D Lifestyle, a national survey by Health Union of more than 400 individuals living with type 2 diabetes (T2D), reveals that patients not only struggle with commonly understood complications, but also numerous lesser known ones that people do not associate with diabetes. [More]
Study identifies conditions required to further develop liver and pancreas cells

Study identifies conditions required to further develop liver and pancreas cells

AMSBIO reports on the recent publication in Nature Protocols1 by Dr Meritxell Huch** and co-workers which describes development of culture conditions that allow the long-term expansion of adult primary tissues from the liver and pancreas into self-assembling 3D organoid cultures. [More]
Nature Methods publishes comparative study of leading Protein-Protein Interaction Networks

Nature Methods publishes comparative study of leading Protein-Protein Interaction Networks

Nature Methods published (online) a comparative study of leading Protein-Protein Interaction (PPI) Networks. [More]
PCSK9 and HMGCR genetic variations that lower bad cholesterol affect risk of cardiovascular events

PCSK9 and HMGCR genetic variations that lower bad cholesterol affect risk of cardiovascular events

In a new study published in the December 1, 2016 issue of The New England Journal of Medicine, researchers at Brigham and Women's Hospital, and a collaboration of international researchers, studied variants in the genes encoding HMGCR and PCSK9 that affect cholesterol levels, and found that variants that lowered LDL (or "bad") cholesterol in each gene were associated with nearly identical protective effects on the risk of cardiovascular events per unit reduction in LDL cholesterol. [More]
TGen and City of Hope collaborate to accelerate precision medicine research

TGen and City of Hope collaborate to accelerate precision medicine research

City of Hope, a world-renowned independent research and cancer and diabetes treatment center, and Translational Genomics Research Institute, a leading biomedical research institute, announced today that they have formed an alliance to make precision medicine a reality for patients. [More]
New study shows link between metabolic syndrome and cognitive abilities in U.S. adolescents

New study shows link between metabolic syndrome and cognitive abilities in U.S. adolescents

A new study of U.S. adolescents shows an association between metabolic syndrome and impairments in reading, attention, and working memory. [More]
Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

The Allen Institute for Cell Science has released the Allen Cell Collection: the first publicly available collection of gene edited, fluorescently tagged human induced pluripotent stem cells that target key cellular structures with unprecedented clarity. [More]
Okayama University researchers find way to prevent replication of influenza viral RNA

Okayama University researchers find way to prevent replication of influenza viral RNA

Researchers at Okayama University have successfully cleaved influenza viral RNA to prevent its replication using novel artificial RNA restriction enzymes in laboratory cell cultures. [More]
Researchers come up with new approach to stabilize vaccines at room temperature

Researchers come up with new approach to stabilize vaccines at room temperature

Shipping vaccines in an unbroken temperature-controlled supply chain (a "cold chain") all the way to recipients is a major logistical and financial challenge in remote areas and developing countries. [More]
Scientists identify microrna that provides clues for quieting auditory hallucinations of schizophrenia

Scientists identify microrna that provides clues for quieting auditory hallucinations of schizophrenia

St. Jude Children's Research Hospital scientists have identified a small RNA (microRNA) that may be essential to restoring normal function in a brain circuit associated with the "voices" and other hallucinations of schizophrenia. [More]
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