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Fitness-related traits in bipolar disorder relatives may explain disease persistence

Fitness-related traits in bipolar disorder relatives may explain disease persistence

Unaffected twins of patients with bipolar disorder show enhanced neurocognitive function and positive temperament traits, research shows. [More]
Researchers reveal important clue for treating absence seizures

Researchers reveal important clue for treating absence seizures

A group of Korean researchers have succeeded in revealing a principle mechanism of a neural network in the human brain, which will provide an important clue to potential treatments for absence seizures. [More]
Research: Seals and sea lions may spread tuberculosis to humans

Research: Seals and sea lions may spread tuberculosis to humans

Tuberculosis is one of the most persistent and deadliest infectious diseases in the world, killing one to two million people each year. [More]
Researchers restore missing repair protein in skeletal muscle of patients with muscular dystrophy

Researchers restore missing repair protein in skeletal muscle of patients with muscular dystrophy

Advances in the treatment of muscular dystrophy: For the first time, a research team has succeeded in restoring a missing repair protein in skeletal muscle of patients with muscular dystrophy. [More]
Study could pave way for preventing brain and cardiac ischemia induced by atherosclerosis

Study could pave way for preventing brain and cardiac ischemia induced by atherosclerosis

A recent Finnish study could pave the way for preventing brain and cardiac ischemia induced by atherosclerosis. Finnish researchers have found that the low-expression variant of fatty acid-binding protein 4 (FABP4), which is particularly common among Finns, reduces the risk of heart attack and stroke. [More]
Newborn screening for SCID holds promise that affected children can lead healthy lives

Newborn screening for SCID holds promise that affected children can lead healthy lives

Using population-based screening outcomes of approximately 3 million infants, a team of scientists across 14 states, including four researchers at the University of Massachusetts Medical School, have shown that newborn screening for severe combined immunodeficiency (SCID) can be successfully implemented across public health newborn screening programs. [More]
Scientists study about rare type of skin cancer, acral melanomas

Scientists study about rare type of skin cancer, acral melanomas

Acral melanomas, the rare type of skin cancer that caused musician Bob Marley's death, are genetically distinct from other types of skin cancer. [More]
FDA approves GlaxoSmithKline’s Arnuity Ellipta for treatment of asthma

FDA approves GlaxoSmithKline’s Arnuity Ellipta for treatment of asthma

GlaxoSmithKline plc today announced that the FDA has approved Arnuity™ Ellipta® (fluticasone furoate inhalation powder), a once-daily inhaled corticosteroid (ICS) medicine for maintenance treatment of asthma as prophylactic therapy in patients aged 12 years and older. Arnuity is not indicated for relief of acute bronchospasm. [More]
Deep sequencing technique opens up new possibilities for finding genetic causes for brain disorder

Deep sequencing technique opens up new possibilities for finding genetic causes for brain disorder

Not every cell in the body is the same genetically, and disease-causing mutations don't necessarily affect every cell—making these mutations easy to miss even with next-generation genomic sequencing. [More]
Scientists explore chili pepper's effect to develop new drug candidate for pain

Scientists explore chili pepper's effect to develop new drug candidate for pain

Biting into a chili pepper causes a burning spiciness that is irresistible to some, but intolerable to others. Scientists exploring the chili pepper's effect are using their findings to develop a new drug candidate for many kinds of pain, which can be caused by inflammation or other problems. [More]
Researchers identify mutated forms of gene that encodes unregulated enzyme driving CML

Researchers identify mutated forms of gene that encodes unregulated enzyme driving CML

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have identified and characterized mutated forms of the gene that encodes BCR-ABL, the unregulated enzyme driving the blood cancer chronic myeloid leukemia (CML). [More]
Genetics may underpin psychiatric comorbidity in bipolar patients

Genetics may underpin psychiatric comorbidity in bipolar patients

Relatives of people with bipolar disorder are at an increased risk of developing not only bipolarity but also other psychiatric disorders, according to Swedish researchers. [More]
Trovagene announces results from clinical studies on urine-based diagnostic test for detection of HPV

Trovagene announces results from clinical studies on urine-based diagnostic test for detection of HPV

Trovagene, Inc., a developer of cell-free molecular diagnostics, announced today that results from two clinical studies will be presented at the 29th International Papillomavirus conference for the Company's urine-based diagnostic test for the detection of high risk strains of Human Papillomavirus. [More]
Seafood mislabeling can cause unwanted exposure to harmful pollutants

Seafood mislabeling can cause unwanted exposure to harmful pollutants

New measurements from fish purchased at retail seafood counters in 10 different states show the extent to which mislabeling can expose consumers to unexpectedly high levels of mercury, a harmful pollutant. [More]
Researchers focus on how exposure to opioids may alter expression of OPRM1 gene

Researchers focus on how exposure to opioids may alter expression of OPRM1 gene

Some infants born with neonatal abstinence syndrome (NAS) secondary to in-utero opioid exposure have a more difficult time going through withdrawal than others, but the underlying reasons are not well understood. [More]
Analysis of Candida glabrata fungus mutations reveals new genes that confer anti-fungal tolerance

Analysis of Candida glabrata fungus mutations reveals new genes that confer anti-fungal tolerance

A group of researchers at the Max F. Perutz Laboratories has created one of the three world's largest gene libraries for the Candida glabrata yeast, which is harmful to humans. [More]
Study examines national impact of newborn screening test for SCID

Study examines national impact of newborn screening test for SCID

Severe combined immunodeficiency (SCID), a potentially life-threatening, but treatable, disorder affecting infants, is twice as common as previously believed, according to a new study that is the first to examine the national impact of this newborn screening test. [More]
KalVista begins Phase I trial of novel plasma kallikrein inhibitor for treatment of DME

KalVista begins Phase I trial of novel plasma kallikrein inhibitor for treatment of DME

KalVista Pharmaceuticals, an ophthalmology company with a focus on diabetic macular edema (DME), today announces that it has begun a Phase I, First in Human, trial of its novel plasma kallikrein inhibitor, KVD001, for the treatment of DME. [More]
Newborn screening indicates that incidence of SCID is higher than previously believed

Newborn screening indicates that incidence of SCID is higher than previously believed

Newborn screening performed in numerous states indicates that the incidence of the potentially life-threatening disorder, severe combined immunodeficiency, is higher than previously believed, at 1 in 58,000 births, although there is a high rate of survival, according to a study in the August 20 issue of JAMA. [More]
Houston Methodist researchers receive $1.6M from NIH to study pathological antibodies

Houston Methodist researchers receive $1.6M from NIH to study pathological antibodies

Transplant immunologists at the Houston Methodist Research Institute will receive about $1.6 million over four years from the National Institute of Allergy and Infectious Diseases to study pathological antibodies produced from activated memory B cells during the chronic rejection of organ transplants. [More]