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Research provides insight into role of APP gene variant in Alzheimer’s disease

New research from the University of Eastern Finland shows that the APP gene variant protecting against Alzheimer's disease significantly decreases plasma beta-amyloid levels in a population cohort.

20 Jun 2017

New breakthrough technology facilitates DNA delivery into drug-resistant bacterial pathogens

Antimicrobial resistance is one of the biggest threats to global health, affecting anyone, at any age, in any country, according to the World Health Organization.

19 Jun 2017

Researchers discover broad role for DNA-cutting enzyme in driving abnormal genetic rearrangements

Researchers studying a DNA-cutting enzyme with a crucial role in regulating the structure of genes have discovered a broad role for its cutting activity in driving abnormal genetic rearrangements called translocations that cause cancer, including leukemias and solid tumors.

16 Jun 2017

Lack of 'editing' in microRNAs can potentially drive brain cancers

SCIENTISTS in the UK and India have observed a "significant" lack of 'editing' in microRNAs in brain tissue of brain cancer patients.

16 Jun 2017

Viral vectors for gene transfer can travel to distant areas in the brain, study shows

Gene transfer is seen as a hopeful therapy for Alzheimer's and Parkinson's patients. The approach involves using harmless laboratory-produced viruses to introduce important genes into the brain cells.

16 Jun 2017

IU study may explain how Wolbachia bacterium prevents mosquitoes from transmitting deadly diseases

A new study from Indiana University may explain how a bacterium called Wolbachia prevents mosquitoes from transmitting deadly diseases such as dengue fever, West Nile virus and Zika.

16 Jun 2017

Penn/CHOP research helps to better understand cause of pediatric and treatment-related leukemias

Certain pediatric leukemias share a common underlying cause with treatment-related secondary leukemias.

16 Jun 2017

Early life stress encodes lifelong susceptibility to depression through alterations in brain reward region

Early life stress encodes lifelong susceptibility to stress through long-lasting transcriptional programming in a brain reward region implicated in mood and depression, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published June 15 in the journal Science.

15 Jun 2017

TSRI scientist and partners receive $7.2 million grant to create new RNA-based treatments for ALS

Professor Matthew Disney of the Department of Chemistry on the Florida campus of The Scripps Research Institute, together with scientists from Mayo Clinic's Florida campus and Johns Hopkins School of Medicine, has been awarded $7.2 million from the National Institute of Neurological Disorders and Stroke of The National Institutes of Health to create new RNA-based treatments for the most common form of amyotrophic lateral sclerosis (ALS), as well as a type of frontotemporal dementia (FTD).

15 Jun 2017

Study identifies new susceptibility loci for lung cancer

Using the OncoArray genotyping platform developed by multiple cancer consortia, a recent large aggregated genomewide association study identifies new susceptibility loci for lung cancer, the leading cause of cancer mortality worldwide.

14 Jun 2017

UAB researchers demonstrate persistence of donor microbes in recipients after fecal transplant

University of Alabama at Birmingham researchers have made the first direct demonstration that fecal donor microbes remained in recipients for months or years after a transplant to treat the diarrhea and colitis caused by recurrent Clostridium difficile infections -- a serious and stubborn cause of diarrhea after an antibiotic treatment for some other illness.

14 Jun 2017

UNC study uncovers crucial function of key enzyme found in virtually all organisms

UNC School of Medicine researchers have cracked a long-standing mystery about an important enzyme found in virtually all organisms other than bacteria.

13 Jun 2017

Study uncovers new genetic markers linked to testicular germ cell tumors

Testicular cancer is relatively rare with only 8,850 cases expected this year in the United States. A majority of testicular cancer, 95 percent of all cases, begins in testicular germ cells, which are the cells responsible for producing sperm.

13 Jun 2017

New HPV vaccine could prevent most infections and millions of cancers

Cervical cancer affects more than half a million women and causes more than a quarter of a million deaths each year globally.

13 Jun 2017

Scientists create method for mapping genome-wide DNA damage caused by chemical carcinogen

Scientists have known for decades that smoking cigarettes causes DNA damage, which leads to lung cancer. Now, for the first time, UNC School of Medicine scientists created a method for effectively mapping that DNA damage at high resolution across the genome.

13 Jun 2017

Dietary practices get reflected in the genes of Europeans, study reveals

A recently published Cornell University study describes how shifts in the diets of Europeans after the introduction of farming 10,000 years ago led to genetic adaptations that favored the dietary trends of the time.

13 Jun 2017

Penn analysis finds genetic factors that could help identify men at increased risk for testicular cancer

An analysis of data from five major studies of testicular cancer has identified new genetic locations that could be susceptible to inherited testicular germ cell tumors.

12 Jun 2017

Anorexia nervosa linked to genetic anomalies on chromosome 12

A large-scale, international whole-genome analysis has now revealed for the first time that anorexia nervosa is associated with genetic anomalies on chromosome 12.

12 Jun 2017

KAUST-led researchers reveal epigenetic mechanism for gene regulation

An epigenetic mechanism regulating gene activity has been revealed by a KAUST-led international team of researchers investigating interactions between the human genome and its environment in adult tissues.

12 Jun 2017

'Mismatch repair' genetic defects drive cancer patient's response to immunotherapy drugs

In an expanded, three-year clinical trial of 86 patients with colorectal and 11 other kinds of cancer that have so-called 'mismatch repair' genetic defects, scientists at Johns Hopkins Medicine and its Bloomberg~Kimmel Institute for Cancer Immunotherapy have found that half of the patients respond to an immunotherapy drug called pembrolizumab.

9 Jun 2017

Genome News and Research

Research provides insight into role of APP gene variant in Alzheimer’s disease

New breakthrough technology facilitates DNA delivery into drug-resistant bacterial pathogens

Researchers discover broad role for DNA-cutting enzyme in driving abnormal genetic rearrangements

Lack of 'editing' in microRNAs can potentially drive brain cancers

Viral vectors for gene transfer can travel to distant areas in the brain, study shows

IU study may explain how Wolbachia bacterium prevents mosquitoes from transmitting deadly diseases

Penn/CHOP research helps to better understand cause of pediatric and treatment-related leukemias

Early life stress encodes lifelong susceptibility to depression through alterations in brain reward region

TSRI scientist and partners receive $7.2 million grant to create new RNA-based treatments for ALS

Study identifies new susceptibility loci for lung cancer

UAB researchers demonstrate persistence of donor microbes in recipients after fecal transplant

UNC study uncovers crucial function of key enzyme found in virtually all organisms

Study uncovers new genetic markers linked to testicular germ cell tumors

New HPV vaccine could prevent most infections and millions of cancers

Scientists create method for mapping genome-wide DNA damage caused by chemical carcinogen

Dietary practices get reflected in the genes of Europeans, study reveals

Penn analysis finds genetic factors that could help identify men at increased risk for testicular cancer

Anorexia nervosa linked to genetic anomalies on chromosome 12

KAUST-led researchers reveal epigenetic mechanism for gene regulation

'Mismatch repair' genetic defects drive cancer patient's response to immunotherapy drugs

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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