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Researchers uncover molecule that may explain smoking-CHD connection

Cigarette smoking accounts for about one-fifth of cases of coronary heart disease, one of the leading causes of death worldwide, but precisely how smoking leads to CHD has long been unclear.

2 May 2017

TACC's supercomputers assist in discovery of new, better chemotherapy drugs

Surgery and radiation remove, kill, or damage cancer cells in a certain area. But chemotherapy -- which uses medicines or drugs to treat cancer -- can work throughout the whole body, killing cancer cells that have spread far from the original tumor.

2 May 2017

Penn study sheds new light on mysterious powers of spider silk genes

They can be stronger than steel at a mere fraction of weight, and also can be tougher and more flexible. Spider silks also tend not to provoke the human immune system. Some even inhibit bacteria and fungi, making them potentially ideal for surgery and medical device applications.

2 May 2017

Study: New gene editing strategy effectively targets cancer-causing ‘fusion genes’ in mouse models

A novel gene therapy using CRISPR genome editing technology effectively targets cancer-causing "fusion genes" and improves survival in mouse models of aggressive liver and prostate cancers, University of Pittsburgh School of Medicine researchers report in a study published online today in Nature Biotechnology.

2 May 2017

New study shows that gene editing technology can shut down HIV-1 replication in animals

A permanent cure for HIV infection remains elusive due to the virus's ability to hide away in latent reservoirs. But now, in new research published in print May 3 in the journal Molecular Therapy, scientists at the Lewis Katz School of Medicine at Temple University and the University of Pittsburgh show that they can excise HIV DNA from the genomes of living animals to eliminate further infection.

2 May 2017

Gene critical for tumor progression also encourages growth of intestinal stem cells, study shows

A gene previously identified as critical for tumor growth in many human cancers also maintains intestinal stem cells and encourages the growth of cells that support them, according to results of a study led by Johns Hopkins researchers.

28 Apr 2017

Scientists rewire mouse stem cells to fight inflammation caused by arthritis

Using new gene-editing technology, researchers have rewired mouse stem cells to fight inflammation caused by arthritis and other chronic conditions.

28 Apr 2017

Scientists use rooster testes to shed light on how germ cells fight viruses

Our bodies are constantly under siege by foreign invaders; viruses, bacteria and parasites that want to infiltrate our cells.

27 Apr 2017

NETRF announces $4 million in collaborative grants to study neuroendocrine tumors

The Neuroendocrine Tumor Research Foundation today announced its largest research commitment ever -- $4 million in collaborative grants -- most from its new Accelerator Grants program to study neuroendocrine tumors, a widely misunderstood, commonly misdiagnosed cancer type, without adequately identified genomic drivers.

27 Apr 2017

Researchers discover new mechanism of epigenetic inheritance in fruit flies

Giacomo Cavalli's team at the Institute of Human Genetics (University of Montpellier / CNRS), in collaboration with the French National Institute for Agricultural Research, has demonstrated the existence of transgenerational epigenetic inheritance among Drosophila fruit flies.

27 Apr 2017

AI key to driving precision medicine in cancer?

It is worth noting that in the U.S. and in many countries, digital pathology is still at a very early stage, compared to many other fields that were digitized 15 or 20 years ago such as radiology. There have been some barriers to the adoption of digital pathology such as regulatory challenges that are only just now being overcome. Recently, the FDA approved the use of whole slide imaging software for primary diagnostics.

27 Apr 2017

Study underscores need for genetic screening to improve safety of experimental stem cell treatments

Regenerative medicine using human pluripotent stem cells to grow transplantable tissue outside the body carries the promise to treat a range of intractable disorders, such as diabetes and Parkinson's disease.

26 Apr 2017

Studies uncover link between immune system, brain structure and memory

The body's immune system performs essential functions, such as defending against bacteria and cancer cells. However, the human brain is separated from immune cells in the bloodstream by the so-called blood-brain barrier.

26 Apr 2017

Scientists use modern techniques to investigate how silver poisons pathogenic microbes

Silver and other metals have been used to fight infections since ancient times. Today, researchers are using sophisticated techniques such as the gene-editing platform Crispr-Cas9 to take a closer look at precisely how silver poisons pathogenic microbes-; and when it fails.

26 Apr 2017

Researchers discover genes linked to resilience against brain pathologies

The pathologies (damage) in the brain that stroke, Alzheimer's disease and other neurological conditions cause in older adults only partially explain the memory loss, reduced reasoning ability and other cognitive impairments that result from these conditions. Little is known about why the effects of brain pathology vary between people who develop it.

26 Apr 2017

Researchers identify new rare genetic variants linked to extreme longevity

The search for the genetic determinants of extreme longevity has been challenging, with the prevalence of centenarians (people older than 100) just one per 5,000 population in developed nations.

25 Apr 2017

Scientists create new technique for studying how chlamydia interacts with immune system

Scientists at the Wellcome Trust Sanger Institute and their collaborators at the University of British Columbia have created an innovative technique for studying how chlamydia interacts with the human immune system.

25 Apr 2017

Combination of genetics and experience gives each individual a unique sense of smell, study finds

Researchers from the Wellcome Trust Sanger Institute and their collaborators have shown that receptors in the noses of mice exposed to certain smells during life are different to genetically similar mice that lived without those smells.

25 Apr 2017

Whole-exome sequencing may routinely miss detecting some disease-causing genes, say researchers

Whole-exome DNA sequencing -- a technology that saves time and money by sequencing only protein-coding regions and not the entire genome -- may routinely miss detecting some genetic variations associated with disease, according to Penn State researchers who have developed new ways to identify such omissions.

24 Apr 2017

$Women at highest genetic risk for fracture benefit most from hormone therapy, study finds$

Women at highest genetic risk for fracture benefit most from hormone therapy, study finds

Women at the highest genetic risk for fracture benefit the most from hormone therapy, according to a first-of-its-kind study led by researchers at the University at Buffalo.

24 Apr 2017

Genome News and Research

Researchers uncover molecule that may explain smoking-CHD connection

TACC's supercomputers assist in discovery of new, better chemotherapy drugs

Penn study sheds new light on mysterious powers of spider silk genes

Study: New gene editing strategy effectively targets cancer-causing ‘fusion genes’ in mouse models

New study shows that gene editing technology can shut down HIV-1 replication in animals

Gene critical for tumor progression also encourages growth of intestinal stem cells, study shows

Scientists rewire mouse stem cells to fight inflammation caused by arthritis

Scientists use rooster testes to shed light on how germ cells fight viruses

NETRF announces $4 million in collaborative grants to study neuroendocrine tumors

Researchers discover new mechanism of epigenetic inheritance in fruit flies

AI key to driving precision medicine in cancer?

Study underscores need for genetic screening to improve safety of experimental stem cell treatments

Studies uncover link between immune system, brain structure and memory

Scientists use modern techniques to investigate how silver poisons pathogenic microbes

Researchers discover genes linked to resilience against brain pathologies

Researchers identify new rare genetic variants linked to extreme longevity

Scientists create new technique for studying how chlamydia interacts with immune system

Combination of genetics and experience gives each individual a unique sense of smell, study finds

Whole-exome sequencing may routinely miss detecting some disease-causing genes, say researchers

Women at highest genetic risk for fracture benefit most from hormone therapy, study finds

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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