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Study shows how epigenetic randomness helps cancer cells proliferate

In a research effort that merged genetics, physics and information theory, a team at the schools of medicine and engineering at The Johns Hopkins University has added significantly to evidence that large regions of the human genome have built-in variability in reversible epigenetic modifications made to their DNA.

27 Mar 2017

New UBC research reveals clues to how bacteria proliferates in lungs of cystic fibrosis patients

New UBC research on bacteria that cause major problems for those with cystic fibrosis reveals clues as to how it proliferates for so long in the lungs and offers new ideas for treatments to explore.

27 Mar 2017

New genetic test may give men better view on how to deal with prostate cancer risk

Scientists are reporting a test which can predict which patients are most at risk from aggressive prostate cancer, and whether they suffer an increased chance of treatment failure.

27 Mar 2017

Scientists call for better basic-clinical genomic research collaborations

In the era of genome sequencing, it's time to update the old "bench-to-bedside" shorthand for how basic research discoveries inform clinical practice, researchers from The Jackson Laboratory, National Human Genome Research Institute and institutions across the U.S. declare in a Leading Edge commentary in Cell.

27 Mar 2017

Study shows how antibiotics increase survival chances of bacteria

Antibiotics harm bacteria and stress them. Trimethoprim (TMP), an antibiotic, inhibits the growth of the bacterium Escherichia coli and induces a stress response.

25 Mar 2017

Researchers report discovery of new gene linked to Tau accumulation in AD

Tau pathology is one of the defining features of Alzheimer disease (AD), which is the most common form of dementia in older age.

25 Mar 2017

Multipronged study of schizophrenia-associated syndrome receives $3.1 million NIH grant

A research team at Emory University is embarking on a multipronged study of 3q29 deletion syndrome, a genetic mutation associated with a 40-fold increased risk for schizophrenia and a range of other neuropsychiatric conditions including mild to moderate intellectual disability, autism and anxiety.

24 Mar 2017

New gene linked to Tau pathology

Investigators at Rush University Medical Center and the Brigham and Women's Hospital in Boston reported the discovery of a new gene that is associated with susceptibility to a common form of brain pathology called Tau that accumulates in several different conditions, including Alzheimer's disease, certain forms of dementia and Parkinsonian syndromes as well as chronic traumatic encephalopathy that occurs with repeated head injuries.

24 Mar 2017

Researchers show shared genetic origin between ALS/MND and schizophrenia

Researchers have shown for the first time that Amyotrophic Lateral Sclerosis (ALS), also known as Motor Neurone Disease (MND) and schizophrenia have a shared genetic origin, indicating that the causes of these diverse conditions are biologically linked.

24 Mar 2017

Study reveals intriguing crosstalk between metabolism and epigenetics in cancer development

A study published in Briefings in Functional Genomics investigated how epigenetics can modulate human's genetic program -- it can emphasize or silence genes.

24 Mar 2017

Researchers develop new way to assemble genome of an organism from scratch

A team spanning Baylor College of Medicine, Rice University, Texas Children's Hospital and the Broad Institute of MIT and Harvard has developed a new way to sequence genomes, which can assemble the genome of an organism, entirely from scratch, dramatically cheaper and faster.

24 Mar 2017

Random DNA copying ‘mistakes’ account for most cancer mutations, study finds

Johns Hopkins Kimmel Cancer Center scientists report data from a new study providing evidence that random, unpredictable DNA copying "mistakes" account for nearly two-thirds of the mutations that cause cancer.

24 Mar 2017

Chromatrap publishes new article comparing efficiency, sensitivity of native and cross-linked ChIP-seq kits

Chromatrap has published a new article that describes a detailed genome wide comparison of native and crosslinked chromatin immunoprecipitation followed by next generation sequencing (ChIP-seq) using the company's patented solid state spin column technology.

From Chromatrap® - Porvair Sciences Ltd 24 Mar 2017

NHGRI researchers use facial recognition software to diagnose rare genetic disease

Researchers with the National Human Genome Research Institute, part of the National Institutes of Health, and their collaborators, have successfully used facial recognition software to diagnose a rare, genetic disease in Africans, Asians and Latin Americans.

24 Mar 2017

OTUD6B gene mutations linked to physical and intellectual deficits

An international team of researchers from institutions around the world, including Baylor College of Medicine, has discovered that mutations of the OTUD6B gene result in a spectrum of physical and intellectual deficits.

24 Mar 2017

MSU lands $727,000 NIH grant to improve use of fish as disease models for human medicine

Michigan State University has landed a $727,000 grant from the National Institutes of Health to improve the use of fish as disease models for human medicine.

23 Mar 2017

Genome sequencing approach opens door to therapy options for rare, neglected cancers

An international team of scientists led by the Icahn School of Medicine at Mount Sinai and UConn School of Medicine have reported the results of a genome sequencing study for an extremely rare form of cancer.

23 Mar 2017

Researchers develop novel genetic score to calculate age-specific risk of Alzheimer's disease

An international team of scientists, led by researchers at University of California San Diego School of Medicine and University of California San Francisco, has developed a novel genetic score that allows individuals to calculate their age-specific risk of developing Alzheimer's disease (AD), based upon genetic information.

22 Mar 2017

USC study close to finding gene involved in cleft lip and palate

A group of researchers has found that three siblings born with cleft lip and palate share a common gene mutation associated with the birth defect.

22 Mar 2017

Penn researcher wins Scientific Innovations Award from Chicago-based Brain Research Foundation

James Eberwine, PhD, the Elmer Holmes Bobst Professor of Systems Pharmacology and Translational Therapeutics at the Perelman School of Medicine at the University of Pennsylvania, has received the 2017 Scientific Innovations Award from the Chicago-based Brain Research Foundation, which supports research for preventing and treating neurological diseases.

22 Mar 2017

Genome News and Research

Study shows how epigenetic randomness helps cancer cells proliferate

New UBC research reveals clues to how bacteria proliferates in lungs of cystic fibrosis patients

New genetic test may give men better view on how to deal with prostate cancer risk

Scientists call for better basic-clinical genomic research collaborations

Study shows how antibiotics increase survival chances of bacteria

Researchers report discovery of new gene linked to Tau accumulation in AD

Multipronged study of schizophrenia-associated syndrome receives $3.1 million NIH grant

New gene linked to Tau pathology

Researchers show shared genetic origin between ALS/MND and schizophrenia

Study reveals intriguing crosstalk between metabolism and epigenetics in cancer development

Researchers develop new way to assemble genome of an organism from scratch

Random DNA copying ‘mistakes’ account for most cancer mutations, study finds

Chromatrap publishes new article comparing efficiency, sensitivity of native and cross-linked ChIP-seq kits

NHGRI researchers use facial recognition software to diagnose rare genetic disease

OTUD6B gene mutations linked to physical and intellectual deficits

MSU lands $727,000 NIH grant to improve use of fish as disease models for human medicine

Genome sequencing approach opens door to therapy options for rare, neglected cancers

Researchers develop novel genetic score to calculate age-specific risk of Alzheimer's disease

USC study close to finding gene involved in cleft lip and palate

Penn researcher wins Scientific Innovations Award from Chicago-based Brain Research Foundation

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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