Genome Editing News and Research

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Dual CRISPR-Cas3 is a promising tool to induce a gigantic genomic deletion and restore dystrophin protein

Researchers evaluated the use of a dual clustered regularly interspaced short palindromic repeats (CRISPR)-Cas3 system.

29 Aug 2023

Two small molecule inhibitors can help improve precision, efficiency of CRISPR-Cas9 gene editing

A new study published in Nature Communications demonstrates how small molecule inhibitors can be used to improve the precision and efficiency of CRISPR-Cas9 gene editing.

25 Aug 2023

Genome editing in the spotlight: genetic disorder carriers' views shape the conversation

Study explores perspectives on the applications of somatic genome editing.

8 Aug 2023

Can genome editing transform ocular disease treatment?

The discovery and development of gene-editing technologies and their applications in managing ocular diseases.

3 Aug 2023

MU researcher receives $3 million grant to use gene editing for investigating the building blocks of disease

In a new study funded by a $3 million grant from the National Institutes of Health (NIH), University of Missouri researcher Kiho Lee, an associate professor in the College of Agriculture, Food and Natural Resources, will use gene editing to investigate the building blocks of disease.

27 Jul 2023

Generating functional parathyroid glands from mouse embryonic stem cells

Regenerative medicine has opened up exciting possibilities in the world of medicine. Now, researchers in Japan are searching for ways to recreate and rebuild body tissues and organs, which may be an alternative cure for diseases.

24 Jul 2023

American Heart Association invests in the future of heart and brain health research

More than 100 scientists from across the U.S. are receiving special grants to support their research work in finding innovative solutions to fight heart disease and stroke.

21 Jul 2023

Tight junctions between cells may play a critical role in gastrulation in human embryos

As a human embryo grows, a set of molecules directs cells as they multiply and take on specific identities and spatial positions within the embryo.

18 Jul 2023

Using CRISPR gene-editing system to build a more sustainable forest

Researchers at North Carolina State University used a CRISPR gene-editing system to breed poplar trees with reduced levels of lignin, the major barrier to sustainable production of wood fibers, while improving their wood properties.

13 Jul 2023

COST Connect: A platform for collaboration and progress in cancer research

Beating cancer is a major challenge for research and innovation in the coming years. By 2030, it is estimated that over 1.5 million people in the EU will succumb to cancer.

6 Jul 2023

Sphere Fluidics expands Cyto-Mine capabilities to meet cGMP requirements for drug manufacture workflows

Sphere Fluidics, a company developing single cell analysis systems underpinned by its patented picodroplet technology, today announced updates to its flagship platform, Cyto-Mine®, enabling it to be compliant with current Good Manufacturing Practice (cGMP) regulations enforced by the US FDA.

From Sphere Fluidics 6 Jul 2023

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

Activation of the NRF2 transcription factor shows promise as a potential treatment approach for non-alcoholic fatty liver disease (NAFLD), a condition associated with oxidative stress and liver damage. By screening FDA-approved drugs, researchers identified six compounds that enhanced NRF2 activity and demonstrated protective effects against oxidative stress and lipid accumulation.

3 Jul 2023

Cell therapy using genome-edited iPS cells could be a new treatment for Fabry disease

Induced pluripotent stem (iPS) cells have a great impact on biology and medicine, and they are expected to improve regenerative medicine.

3 Jul 2023

Base editing shows promise for treating sickle cell disease and beta thalassemia

Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and beta thalassemia.

3 Jul 2023

How New Genomic Techniques can make agricultural production more sustainable

The EU Commission announced the release of a draft proposal for a reformed regulation of New Genomic Techniques (NGTs) that is expected to be published in early July 2023.

29 Jun 2023

AI may hold the key to a sharper and more precise DNA scissor technology

Artificial Intelligence may be the key to more precise and effective gene therapy treatments. A new study from Aarhus University has found, that applying AI predictions of protein structures enhances the DNA scissor technology CRISPR, by making the cuts in a patient's DNA more precise.

29 Jun 2023

First programmable RNA-guided system found in eukaryotes

A team of researchers led by Feng Zhang at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT has uncovered the first programmable RNA-guided system in eukaryotes -; organisms that include fungi, plants, and animals.

28 Jun 2023

New kidney cancer model highlights molecular targets and genomic events that drive metastasis

Researchers at The University of Texas MD Anderson Cancer have engineered a new model of aggressive renal cell carcinoma (RCC), highlighting molecular targets and genomic events that trigger chromosomal instability and drive metastatic progression.

26 Jun 2023

New study warns of dangers of gene editing in human embryos

Scientists have discovered that the cells of early human embryos are often unable to repair damage to their DNA.

26 Jun 2023

New project aims to improve the efficacy and safety of CAR T therapies for solid tumors

Partners in the international consortium CAR T-REX announce the awarding of a highly competitive EIC Pathfinder Open grant, following the positive evaluation of their project entitled 'CAR T Cells Rewired to Prevent EXhaustion in the Tumour Microenvironment'.

23 Jun 2023

Genome Editing News and Research

Dual CRISPR-Cas3 is a promising tool to induce a gigantic genomic deletion and restore dystrophin protein

Two small molecule inhibitors can help improve precision, efficiency of CRISPR-Cas9 gene editing

Genome editing in the spotlight: genetic disorder carriers' views shape the conversation

Can genome editing transform ocular disease treatment?

MU researcher receives $3 million grant to use gene editing for investigating the building blocks of disease

Generating functional parathyroid glands from mouse embryonic stem cells

American Heart Association invests in the future of heart and brain health research

Tight junctions between cells may play a critical role in gastrulation in human embryos

Using CRISPR gene-editing system to build a more sustainable forest

COST Connect: A platform for collaboration and progress in cancer research

Sphere Fluidics expands Cyto-Mine capabilities to meet cGMP requirements for drug manufacture workflows

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

Cell therapy using genome-edited iPS cells could be a new treatment for Fabry disease

Base editing shows promise for treating sickle cell disease and beta thalassemia

How New Genomic Techniques can make agricultural production more sustainable

AI may hold the key to a sharper and more precise DNA scissor technology

First programmable RNA-guided system found in eukaryotes

New kidney cancer model highlights molecular targets and genomic events that drive metastasis

New study warns of dangers of gene editing in human embryos

New project aims to improve the efficacy and safety of CAR T therapies for solid tumors

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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