Genomic News and Research

RSS

New clinical genomic testing helps identify mutations that drive childhood melanoma

Comprehensive clinical genomic testing of an adolescent patient, including whole genome sequencing, helped researchers identify mutations in a single gene that drive the most common childhood melanoma.

5 Mar 2019

Microbes causing cystic fibrosis change rapidly within 2-3 years after first infection

A new study, recently published in Nature Communications, has looked at infections in Danish youth with CF over a period of 10 years. This is the largest longitudinal study to date of the evolution - both involving traits and genes - of the disease-causing microbes that persistently infect young CF-patients.

5 Mar 2019

Beckman Coulter Life Sciences and Apostle announce exclusive liquid biopsy partnership

Launch of Apostle MiniMax High Efficiency Cell-Free DNA Isolation Kit through an exclusive partnership with Apostle, a liquid biopsy company.

From Beckman Coulter Life Sciences - Automation and Genomics 4 Mar 2019

Many genes contribute to risk for Tourette's syndrome, genetic study shows

A meta-analysis of multiple studies into the genetic background of Tourette's syndrome (TS) - a neurodevelopmental disorder characterized by chronic involuntary motor and vocal tics - finds that variants in hundreds of genes, working in combination, contribute to the development of the syndrome and suggests that Tourette's is part of a continuous spectrum of tic disorders, ranging from mild, sometimes transient tics to severe cases that can include psychiatric symptoms.

1 Mar 2019

Research identifies super-enhancers as novel target for pancreatic ductal adenocarcinoma

Differential H3K27AC marks were identified at enhancer regions of genes including c-MYC, MED1, OCT-4, NANOG, and SOX2 that can act as super-enhancers (SE), cluster of genes in non-cancerous, cancerous and metastatic PDAC cell lines.

1 Mar 2019

Breakthrough chromosome imaging could aid in development of new treatments

Chromosomes, each containing hundreds or thousands of genes, act like a detailed instruction manual for how cells should develop and behave.

28 Feb 2019

Study: Chikungunya virus arrived in Brazil at least one year before it was detected

New evidence suggests that Chikungunya virus arrived in Brazil at least one year earlier than it was detected by public health surveillance systems.

26 Feb 2019

Study uncovers potential role of Foxp1 protein in control of autoimmune diseases

Scientists at the Higher School of Economics, the Institute of Bioorganic Chemistry of the Russian Academy of Sciences, and the Memorial Sloan Kettering Cancer Center created a genetic model that helps to understand how the body restrains autoimmune and oncological diseases.

26 Feb 2019

Researchers outline targeted therapeutic strategy for triple-negative breast cancer

New findings put forth by the University of Maryland Fischell Department of Bioengineering and researchers from four other academic institutions outline a targeted therapeutic strategy to treat triple-negative breast cancer - a potential first for the particularly aggressive form of breast cancer.

26 Feb 2019

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

As the biomedical field races to develop therapies based on an individual's genetic makeup, a City of Hope scientist and his colleagues found that some commercial cell lines used for countless laboratory studies have mislabeled ancestry when it comes to minorities.

25 Feb 2019

Scientists identify cause of devastating pediatric brain disorder

An international effort led by physician-scientists at Rady Children's Institute for Genomic Medicine, in collaboration with a team at the Montreal Children's Hospital of the McGill University Health Centre, has identified the cause of a devastating pediatric brain disorder paving the way for the first step in developing potential therapies for this rare neurodegenerative condition.

25 Feb 2019

New analysis highlights increasing focus of early-stage clinical trials on rare cancers

The proportion of early-stage drug trials tackling the biggest cancer killers has declined sharply since the early 1990s as less common tumor types receive increasing attention, according to new research to be presented during the International Congress on Targeted Anticancer Therapies 2019, taking place from today to 27 February in Paris, France.

25 Feb 2019

Biologist uses new grant to find ways to eliminate schistosomiasis

A biologist at The University of Texas at Arlington is using a new grant to look for ways to finish off a disease that has stubbornly resisted all attempts to eradicate it.

22 Feb 2019

UCL and AIIMS collaborates to increase academic and student exchange

UCL and the All India Institute of Medical Sciences have entered into a new partnership which will enable much closer research collaboration and will explore opportunities to increase academic and student exchange between the institutions.

22 Feb 2019

Why melanoma tumors in the brain may be worse?

Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites.

20 Feb 2019

New computational tool searches for factors that cause specific diseases

Researchers from Boston University School of Medicine have developed and tested a new computational tool, Candidate Driver Analysis, which will search for combinations of factors that are likely to cause a specific disease.

20 Feb 2019

Physicians graduated outside the U.S. offer better care for Medicare patients with complex needs

A study by a Massachusetts General Hospital research team indicates that internal medicine physicians who are graduates of medical schools outside the U.S. care for Medicare patients with more complex medical needs than those cared for by graduates of American medical schools.

20 Feb 2019

First molecular test predicts treatment response for kidney cancer

Immunotherapy drugs such as PD-L1 checkpoint inhibitors represent the front-line treatment for kidney cancer. But immunotherapy is expensive, benefits only a subset of patients and is futile in the majority of patients.

19 Feb 2019

Study shows how 3D organization of genetic material helps perpetuate the species

From fathers to children, the delivery of hereditary information requires the careful packing of DNA in sperm. But just how nature packages this DNA to prepare offspring isn't clear.

19 Feb 2019

Researchers identify multiple genetic variants associated with body fat distribution

A new breakthrough from the Genetic Investigation of Anthropometric Traits consortium, which includes many public health researchers from the University of North Carolina at Chapel Hill, identifies multiple genetic variants associated with how the body regulates and distributes body-fat tissue.

18 Feb 2019

Genomic News and Research

New clinical genomic testing helps identify mutations that drive childhood melanoma

Microbes causing cystic fibrosis change rapidly within 2-3 years after first infection

Beckman Coulter Life Sciences and Apostle announce exclusive liquid biopsy partnership

Many genes contribute to risk for Tourette's syndrome, genetic study shows

Research identifies super-enhancers as novel target for pancreatic ductal adenocarcinoma

Breakthrough chromosome imaging could aid in development of new treatments

Study: Chikungunya virus arrived in Brazil at least one year before it was detected

Study uncovers potential role of Foxp1 protein in control of autoimmune diseases

Researchers outline targeted therapeutic strategy for triple-negative breast cancer

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

Scientists identify cause of devastating pediatric brain disorder

New analysis highlights increasing focus of early-stage clinical trials on rare cancers

Biologist uses new grant to find ways to eliminate schistosomiasis

UCL and AIIMS collaborates to increase academic and student exchange

Why melanoma tumors in the brain may be worse?

New computational tool searches for factors that cause specific diseases

Physicians graduated outside the U.S. offer better care for Medicare patients with complex needs

First molecular test predicts treatment response for kidney cancer

Study shows how 3D organization of genetic material helps perpetuate the species

Researchers identify multiple genetic variants associated with body fat distribution

Genetics & Genomics - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest News