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Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

Horizon Discovery Group today announces that it has entered into an exclusive target discovery partnership with C4XD, a pioneering drug discovery company.

From Revvity 19 Dec 2018

New genetic testing method increases the precision of biomarker analysis

Estonian scientists have announced the invention of a genetic testing technology that allows the number of clinical biomarkers to be analyzed at the single-molecule level, which enhances the sensitivity of tests in precision medicine and will make them more affordable in future.

18 Dec 2018

Advanced method can help detect multiple markers that contribute to Alzheimer's disease

In biomedical research, plant breeding, and countless other endeavors, geneticists are on the hunt for the specific genes responsible for disease susceptibility, yield, and other traits of interest.

17 Dec 2018

TGen receives PayPal grant to underwrite costs of genetic tests for children with rare disorders

The Translational Genomics Research Institute, an affiliate of City of Hope, today announced a $10,000 grant from PayPal Gives, which will help underwrite the costs of genetic tests for children with rare disorders.

17 Dec 2018

Researcher conducts study to investigate peripheral blood markers of Alzheimer's disease

Β-amyloid formation, an indicative element of Alzheimer's disease, is a consequence of alternative expression of enzymes involved in the cleavage of amyloid precursor protein, leading to dementia in elderly populations.

17 Dec 2018

Study finds epigenetic differences in the brains of individuals with schizophrenia

A study using a PET scan tracer developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital has identified, for the first time, epigenetic differences between the brains of individuals with schizophrenia and those of unaffected study participants.

17 Dec 2018

Using machine learning to predict risk of developing life-threatening infections

Staphylococcus epidermidis is an ubiquitous colonizer of healthy human skin, but it is also a notorious source of serious nosocomial infections with indwelling devices and surgical procedures such as hip replacements.

14 Dec 2018

New drug shows promise in treating sarcomas

A new compound that targets a receptor within sarcoma cancer cells shrank tumors and hampered their ability to spread in mice and pigs, a study from researchers at the University of Illinois reports.

14 Dec 2018

Acne could have a genetic basis find researchers promising new cure

In one of the pioneering genetic studies of acne, it has been seen that the condition that affects millions of teenagers and adults could have a genetic basis. This genetic study can also pave the way for new and accurate treatment for acne promise researchers. The study results are published in the latest issue of the journal Nature Communications.

13 Dec 2018

New mouse model shows potential for rapid identification of promising muscular dystrophy therapies

A Massachusetts General Hospital research team has created a new mouse model of a common form of muscular dystrophy with the potential of rapidly distinguishing promising therapeutic drugs from those unlikely to be successful.

13 Dec 2018

Blood test helps identify distinct molecular signatures in children with cystic fibrosis

Researchers at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago, and colleagues, used a blood test and microarray technology to identify distinct molecular signatures in children with cystic fibrosis.

12 Dec 2018

Genetics study offers hope for new acne treatment

A discovery by researchers from the School of Basic & Medical Biosciences and NIHR Guy's and St Thomas' Biomedical Research Centre could lead to new treatments for severe acne. Scientists found 15 genome regions linked to developing the condition.

12 Dec 2018

Faster, cheaper test has potential to enhance prostate cancer evaluation

For men newly diagnosed with prostate cancer or patients previously treated, the risk of metastasis is a crucial determinant of whether to choose conservative management or undergo further treatment.

12 Dec 2018

Ezogabine treatment reduces motor neuron excitability in ALS patients, study shows

Brian Wainger, MD, PhD, of the Healey Center for ALS at Massachusetts General Hospital presented initial, top-level results of a recently completed phase 2 clinical trial of ezogabine (also called retigabine) on December 9 at the Motor Neurone Disease Association annual meeting in Glasgow, Scotland.

11 Dec 2018

New data from TAILORx trial confirms lack of chemo benefit regardless of race or ethnicity

An analysis of race and ethnicity data from the TAILORx clinical trial was presented at the 2018 San Antonio Breast Cancer Symposium.

10 Dec 2018

Black women with breast cancer have worse outcomes despite receiving equivalent treatments as white women

Even with equivalent treatments in women with hormone receptor-positive, HER2-negative breast cancer, black women had significantly higher breast cancer recurrence and increased overall mortality compared to white women in a large phase III clinical trial, TAILORx, according to data presented at the 2018 San Antonio Breast Cancer Symposium, held Dec. 4-8.

7 Dec 2018

Genomic News and Research

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

New genetic testing method increases the precision of biomarker analysis

Advanced method can help detect multiple markers that contribute to Alzheimer's disease

TGen receives PayPal grant to underwrite costs of genetic tests for children with rare disorders

Researcher conducts study to investigate peripheral blood markers of Alzheimer's disease

Study finds epigenetic differences in the brains of individuals with schizophrenia

Using machine learning to predict risk of developing life-threatening infections

New drug shows promise in treating sarcomas

Acne could have a genetic basis find researchers promising new cure

New mouse model shows potential for rapid identification of promising muscular dystrophy therapies

Blood test helps identify distinct molecular signatures in children with cystic fibrosis

Genetics study offers hope for new acne treatment

Faster, cheaper test has potential to enhance prostate cancer evaluation

Ezogabine treatment reduces motor neuron excitability in ALS patients, study shows

New data from TAILORx trial confirms lack of chemo benefit regardless of race or ethnicity

Black women with breast cancer have worse outcomes despite receiving equivalent treatments as white women

New technology for profiling genetic makeup of myeloma tumor cells developed

Elevated hormone flags liver disease in mice with serious genomic disorder

Study reveals how the absence of Dna2 enzyme affects chromosome instability

New massive sequencing platform implemented for double factor preimplantation genetic testing

Genetics & Genomics - Second Edition eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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