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A new perspective on evolution provided by fly testes

The male testes are important areas for biological innovation, as well as being a factory for sperm. In exciting new biological research a team of scientists has found that the testes are also a hotspot for the production ofnew genes.

19 Aug 2019

Advanced method to accurately detect low-level somatic mutation in intractable epilepsy

KAIST medical scientists have developed an advanced method for perfectly detecting low-level somatic mutation in patients with intractable epilepsy. Their study showed that deep sequencing replicates of major focal epilepsy genes accurately and efficiently identified low-level somatic mutations in intractable epilepsy.

16 Aug 2019

Study reveals Lassa virus' soft spot

As this year's Lassa fever outbreak in Nigeria is finally ebbing, the total tally came to more than 600 infected people, one-quarter of them dead. Thousands more die each year, uncounted in rural villages throughout West Africa.

9 Aug 2019

Ancient epigenetic change deactivates some genes linked to cancer

An epigenetic change, a form of DNA control, that deactivates some genes linked to cancer late in human development has been conserved for more than 400 million years, new research led by the Garvan Institute of Medical Research suggests.

11 Jul 2019

New telementoring program seeks to improve quality of care for breast cancer patients

A new program led by The University of Kansas Cancer Center seeks to improve community oncology providers' knowledge of genetic testing in breast cancer patients, as well as provide tools to allow genetic counseling and testing to be incorporated in their clinical practice.

2 Jul 2019

Identifying colorectal cancer subtypes in patients could help provide better care

Colorectal cancer is the second leading cause of cancer death in the U.S., expected to cause about 51,000 deaths in 2019. But until now, it was unclear which drugs were most effective for which patients.

12 Jun 2019

Russian researcher announces plans to create more CRISPR-edited babies

A researcher has announced controversial plans to create gene-edited babies, dividing the scientific community.

12 Jun 2019

Identifying subtype of colorectal cancer may help oncologists determine most effective treatment

12 Jun 2019

Learned avoidance behavior can be inherited for multiple generations, say Princeton researchers

Princeton University researchers have discovered that learned behaviors can be inherited for multiple generations in C. elegans, transmitted from parent to progeny via eggs and sperm cells.

7 Jun 2019

Men who delay fatherhood put health of partners, unborn children at risk

Men who delay starting a family have a ticking "biological clock" -- just like women -- that may affect the health of their partners and children, according to Rutgers researchers.

13 May 2019

Will gene-editing of human embryos ever be justifiable?

World-leading medical ethicist Professor Arthur Caplan has published a series of recommendations with the aim of addressing worldwide concerns over gene editing of human embryos.

30 Apr 2019

New computer program developed by TGen lights up cancer-causing genetic mutations

By conjuring the spell "Lumos!" wizards in the mythical world of Harry Potter could light up the tip of their magic wands and illuminate their surroundings. So, too, does LumosVar, a computer program developed by the Translational Genomics Research Institute, "light up" cancer-causing genetic Var-ients, or mutations, illuminating how physicians might best treat their patients.

21 Mar 2019

Gene editing and designer babies experiments face global moratorium

Powerful gene editing tools could soon face a global regulations on their use on human embryos, sperms or eggs.

20 Mar 2019

Researchers track effects of epigenetic marks carried by sperm chromosomes

As an organism grows and responds to its environment, genes in its cells are constantly turning on and off, with different patterns of gene expression in different cells. But can changes in gene expression be passed on from parents to their children and subsequent generations?

20 Mar 2019

Gene editing regulations to be tightened

Last week a group of scientists from across the globe came together to sign a moratorium on gene editing in humans.

20 Mar 2019

Call for halt to human gene editing and designer babies experiments

Powerful gene editing tools could soon face a global regulations on their use on human embryos, sperms or eggs.

18 Mar 2019

Genetic variations in a fourth gene associated with higher ALL risk in Hispanic children

St. Jude Children's Research Hospital scientists have identified genetic variations in a fourth gene that are associated with an increased risk of acute lymphoblastic leukemia in Hispanic children. The research appears today in the journal Blood.

15 Feb 2019

Cell membrane complexes may be new target for drugs to kill cancer cells

Old molecules and new complexes: researchers at Hollings Cancer Center at the Medical University of South Carolina have discovered cell membrane complexes called ceramidosomes that may be a new target for drugs to kill cancer cells.

13 Feb 2019

Cloning-free Nested CRISPR uses long DNA fragments for efficient gene editing

CRISPR is a technique that is revolutionizing biomedical research through high-precision genome editing. However, even though it allows the creation or correction of mutations consisting of a single or few nucleotides with relative ease, it still possesses limitations upon introducing larger fragments of DNA in the genome.

8 Feb 2019

Study sheds new light on male infertility

Hope has emerged for infertile men as scientists at Newcastle University have understood the importance of a gene in regulating the production of fully-functioning sperm.

24 Jan 2019