Glioblastoma News and Research

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Glioblastoma is the most aggressive and malignant form of glioma, a type of primary brain cancer. Surgery is often used to treat gliomas, along with radiation. However, since surgery and radiation fail to cure the disease, doctors may turn to additional radiation or chemotherapy. In early stages glioblastoma tumors often grow without symptoms and therefore can become quite large before symptoms arise. When the tumor becomes symptomatic, tumor growth is usually very rapid and is accompanied by altered brain function, and if left untreated the disease becomes lethal. Although primary treatment is often successful in temporarily stopping the progression of the tumor, glioblastomas almost always recur and become lethal.
Neuro-oncology scientists discover unique molecular mechanism that maintains glioma stem cells

Neuro-oncology scientists discover unique molecular mechanism that maintains glioma stem cells

Researchers devise strategy to target Achilles heel of nervous system cancers

Researchers devise strategy to target Achilles heel of nervous system cancers

Scientists discover how CD44s molecule gives brain cancer cells a survival advantage

Scientists discover how CD44s molecule gives brain cancer cells a survival advantage

BWH researchers use specific microRNA to identify, alter makeup of glioblastoma subtypes

BWH researchers use specific microRNA to identify, alter makeup of glioblastoma subtypes

Study demonstrates potential nanoparticle-based therapeutic strategy for deadly brain tumors

Study demonstrates potential nanoparticle-based therapeutic strategy for deadly brain tumors

Targeting acid metabolite reduces size and spread of breast cancer

Targeting acid metabolite reduces size and spread of breast cancer

Study shows potential of whole genome sequencing and AI to help clinicians scale precision oncology

Study shows potential of whole genome sequencing and AI to help clinicians scale precision oncology

Scientists reveal role of cellular prion protein in development of NF2-related tumors

Scientists reveal role of cellular prion protein in development of NF2-related tumors

High-throughput screening technique reveals new brain cancer drug targets

High-throughput screening technique reveals new brain cancer drug targets

Research reveals biological processes that underlie comorbidity between Alzheimer's disease and cancer

Research reveals biological processes that underlie comorbidity between Alzheimer's disease and cancer

Wyss Institute researchers develop new capture technology for cancer diagnostics

Wyss Institute researchers develop new capture technology for cancer diagnostics

Cells key to blood vessel formation can also produce tumors and enable their spread

Cells key to blood vessel formation can also produce tumors and enable their spread

Lack of 'editing' in microRNAs can potentially drive brain cancers

Lack of 'editing' in microRNAs can potentially drive brain cancers

New treatment strategy may destroy difficult-to-treat brain tumors

New treatment strategy may destroy difficult-to-treat brain tumors

Study establishes BCL6 protein as potential marker to predict overall survival of GBM patients

Study establishes BCL6 protein as potential marker to predict overall survival of GBM patients

Researchers develop new approach to build better blood-brain barrier model

Researchers develop new approach to build better blood-brain barrier model

Cancer Research UK-funded scientists to test effect of Zika virus on glioblastoma

Cancer Research UK-funded scientists to test effect of Zika virus on glioblastoma

New spherical nucleic acid drug crosses blood-brain barrier to target brain tumors in animals

New spherical nucleic acid drug crosses blood-brain barrier to target brain tumors in animals

UAB spinoff develops drug-resistant immunotherapy to combat solid tumors

UAB spinoff develops drug-resistant immunotherapy to combat solid tumors

Scientists map genetic changes that help drive aggressive brain tumor

Scientists map genetic changes that help drive aggressive brain tumor