Glioblastoma News and Research

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Glioblastoma is the most aggressive and malignant form of glioma, a type of primary brain cancer. Surgery is often used to treat gliomas, along with radiation. However, since surgery and radiation fail to cure the disease, doctors may turn to additional radiation or chemotherapy. In early stages glioblastoma tumors often grow without symptoms and therefore can become quite large before symptoms arise. When the tumor becomes symptomatic, tumor growth is usually very rapid and is accompanied by altered brain function, and if left untreated the disease becomes lethal. Although primary treatment is often successful in temporarily stopping the progression of the tumor, glioblastomas almost always recur and become lethal.
Cells key to blood vessel formation can also produce tumors and enable their spread

Cells key to blood vessel formation can also produce tumors and enable their spread

Lack of 'editing' in microRNAs can potentially drive brain cancers

Lack of 'editing' in microRNAs can potentially drive brain cancers

New treatment strategy may destroy difficult-to-treat brain tumors

New treatment strategy may destroy difficult-to-treat brain tumors

Study establishes BCL6 protein as potential marker to predict overall survival of GBM patients

Study establishes BCL6 protein as potential marker to predict overall survival of GBM patients

Researchers develop new approach to build better blood-brain barrier model

Researchers develop new approach to build better blood-brain barrier model

Cancer Research UK-funded scientists to test effect of Zika virus on glioblastoma

Cancer Research UK-funded scientists to test effect of Zika virus on glioblastoma

New spherical nucleic acid drug crosses blood-brain barrier to target brain tumors in animals

New spherical nucleic acid drug crosses blood-brain barrier to target brain tumors in animals

UAB spinoff develops drug-resistant immunotherapy to combat solid tumors

UAB spinoff develops drug-resistant immunotherapy to combat solid tumors

Scientists map genetic changes that help drive aggressive brain tumor

Scientists map genetic changes that help drive aggressive brain tumor

Brain cancer patient treated with malaria drug shows dramatic improvement

Brain cancer patient treated with malaria drug shows dramatic improvement

Vaccine-chemotherapy combination may improve survival for glioblastoma patients

Vaccine-chemotherapy combination may improve survival for glioblastoma patients

PID1 gene increases killing effect of chemotherapy drugs on brain tumor cells

PID1 gene increases killing effect of chemotherapy drugs on brain tumor cells

Combination of TTFields with standard therapies may improve survival in pancreatic cancer patients

Combination of TTFields with standard therapies may improve survival in pancreatic cancer patients

Phase 2 study shows encouraging results for TTFields therapy in treating recurrent ovarian cancer

Phase 2 study shows encouraging results for TTFields therapy in treating recurrent ovarian cancer

Study identifies specific genetic risk factors that increase susceptibility to gliomas

Study identifies specific genetic risk factors that increase susceptibility to gliomas

City of Hope researchers to highlight basic cancer research and population studies at AACR meeting

City of Hope researchers to highlight basic cancer research and population studies at AACR meeting

New clinical approach offers hope for patients with aggressive brain cancer

New clinical approach offers hope for patients with aggressive brain cancer

Combined therapy extends survival of older patients with glioblastoma, clinical study shows

Combined therapy extends survival of older patients with glioblastoma, clinical study shows

Antibody treats pediatric brain tumors safely and effectively in mice

Antibody treats pediatric brain tumors safely and effectively in mice

Rheumatoid arthritis drug blocks metabolic pathway, reduces breast cancer tumors in mice

Rheumatoid arthritis drug blocks metabolic pathway, reduces breast cancer tumors in mice