Glioblastoma News and Research RSS Feed - Glioblastoma News and Research

Glioblastoma is the most aggressive and malignant form of glioma, a type of primary brain cancer. Surgery is often used to treat gliomas, along with radiation. However, since surgery and radiation fail to cure the disease, doctors may turn to additional radiation or chemotherapy. In early stages glioblastoma tumors often grow without symptoms and therefore can become quite large before symptoms arise. When the tumor becomes symptomatic, tumor growth is usually very rapid and is accompanied by altered brain function, and if left untreated the disease becomes lethal. Although primary treatment is often successful in temporarily stopping the progression of the tumor, glioblastomas almost always recur and become lethal.
Researchers uncover structure of cancer cell receptor protein that paves way for drug development

Researchers uncover structure of cancer cell receptor protein that paves way for drug development

A team of researchers from Case Western Reserve University School of Medicine has helped uncover the elusive structure of a cancer cell receptor protein that can be leveraged to fight disease progression. [More]
TGen scientists identify potent inhibitory compound for treatment against glioblastoma

TGen scientists identify potent inhibitory compound for treatment against glioblastoma

A study led by scientists at the Translational Genomics Research Institute has identified "a potent inhibitory compound" in the elusive hunt for an improved treatment against glioblastoma, the most common and deadly type of adult brain cancer. [More]
Researchers identify brain cell types from cell culture of adult human neurons

Researchers identify brain cell types from cell culture of adult human neurons

Studying brain disorders in people and developing drugs to treat them has been slowed by the inability to investigate single living cells from adult patients [More]
Duke researchers use cancer-seeking salmonella to treat glioblastoma

Duke researchers use cancer-seeking salmonella to treat glioblastoma

Biomedical engineers at Duke University have recruited an unlikely ally in the fight against the deadliest form of brain cancer -- a strain of salmonella that usually causes food poisoning. [More]
New research suggests novel combination approach to fight against gliomas

New research suggests novel combination approach to fight against gliomas

"Devastating" and "dismal." That's how leading researchers describe the present outlook for malignant brain tumors. The median survival rate for patients with glioblastoma multiforme, or GBM, is a mere 14.2 months. [More]
NFCR scientists develop new treatment for brain cancer

NFCR scientists develop new treatment for brain cancer

The National Foundation for Cancer Research (NFCR) today congratulated Dr. Web Cavenee and Dr. Paul B. Fisher on their discovery of a new pharmacological agent to treat glioblastoma multiforme (GBM), the deadliest brain cancer, which they have been developing together with NFCR support. [More]
Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

In experiments on mice with a form of aggressive brain cancer, Johns Hopkins researchers have shown that localized chemotherapy delivered directly to the brain rather than given systemically may be the best way to keep the immune system intact and strong when immunotherapy is also part of the treatment. [More]
Novel genomics model allows personalized approach to radiation therapy

Novel genomics model allows personalized approach to radiation therapy

Cancer therapeutics is currently in the era of precision medicine - personalized medicine for individual patients based on their tumor biology. [More]
New graphene system can detect activity levels of interfaced normal and cancer cells

New graphene system can detect activity levels of interfaced normal and cancer cells

What can't graphene do? You can scratch "detect cancer" off of that list. By interfacing brain cells onto graphene, researchers at the University of Illinois at Chicago have shown they can differentiate a single hyperactive cancerous cell from a normal cell, pointing the way to developing a simple, noninvasive tool for early cancer diagnosis. [More]
Researchers identify attractive drug candidate to target glioma tumors

Researchers identify attractive drug candidate to target glioma tumors

In a paper published today in Cancer Research, researchers: 1) identify a biomarker enzyme associated with aggressive glioma brain tumors, 2) reveal the regulatory mechanism for that enzyme, and 3) demonstrate potent efficacy, using a mouse model of glioma, for a small molecule inhibitor they have developed. [More]
Lactate component responsible for anti-tumor effects of plasma medicine, research shows

Lactate component responsible for anti-tumor effects of plasma medicine, research shows

Physical plasma is one of the four fundamental states of matter, together with solid, liquid, and gas, and can be completely or partially ionized (thermal/hot or non-thermal/cold plasma, respectively). [More]
Metabolic pathway that shows potential to slow aging may drive brain cancer

Metabolic pathway that shows potential to slow aging may drive brain cancer

While a particular metabolic pathway shows potential to slow down the aging process, new research indicates a downside: That same pathway may drive brain cancer. [More]
Ancient Japanese art inspires groundbreaking technique to create ‘artificial brains’

Ancient Japanese art inspires groundbreaking technique to create ‘artificial brains’

The ancient Japanese art of flower arranging was the inspiration for a groundbreaking technique to create tiny "artificial brains" that could be used to develop personalized cancer treatments. [More]
Researchers design smart drug to treat patients with most aggressive brain cancers

Researchers design smart drug to treat patients with most aggressive brain cancers

Physicians and researchers at Houston Methodist Hospital have designed a new drug to treat patients with the most aggressive, incurable brain cancers. [More]
Researchers identify pathway that helps cancer cells to aggressively spread in the brain

Researchers identify pathway that helps cancer cells to aggressively spread in the brain

Glioblastoma multiforme remains the most common and highly lethal brain cancer and is known for its ability to relapse. [More]
Cancer researchers identify important driver of tumor cell invasion in glioblastoma

Cancer researchers identify important driver of tumor cell invasion in glioblastoma

University of Hawai'i Cancer Center researchers have identified an essential driver of tumor cell invasion in glioblastoma, the most aggressive form of brain cancer that can occur at any age. [More]
Deficiency of tumor suppressor gene may allow brain cancer cells to survive outside niches

Deficiency of tumor suppressor gene may allow brain cancer cells to survive outside niches

Astronauts survive in space by wearing high-tech space suits. But how do brain cancer cells thrive when they migrate to inhospitable sites within the brain? [More]
TSRI study suggests new approach to limit tumor growth by targeting immune system cells

TSRI study suggests new approach to limit tumor growth by targeting immune system cells

A new study led by scientists at The Scripps Research Institute suggests there may be a way to limit tumor growth by targeting immune system cells called macrophages. [More]
DNAtrix enters into license agreement with University of Florida to develop new oncolytic virus platform

DNAtrix enters into license agreement with University of Florida to develop new oncolytic virus platform

DNAtrix, a clinical stage biotechnology company developing virus-driven immunotherapies for cancer, announced it has entered into an exclusive license agreement with the University of Florida, Gainesville to develop a novel oncolytic virus platform. [More]
Characteristics of brain tumour provide insight into survival, treatment options for patients over 70

Characteristics of brain tumour provide insight into survival, treatment options for patients over 70

Characteristics like seizures, location of the tumour, and pressure in the brain, give insight into length of survival and treatment options for brain tumour patients over the age of 70, according to new research presented at the National Cancer Research Institute's Cancer Conference in Liverpool. [More]
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