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Glioma is a cancer of the brain that begins in glial cells (cells that surround and support nerve cells).
Precision medicine advances diagnosis and treatment of children with brain tumors

Precision medicine advances diagnosis and treatment of children with brain tumors

Precision medicine - in which diagnosis and treatments are keyed to the genetic susceptibilities of individual cancers - has advanced to the point where it can now impact the care of a majority of children with brain tumors, a new study by investigators at Dana-Farber/Boston Children's Cancer and Blood Disorders Center suggests. [More]
NCCN publishes new easy-to-understand patient education resources focused on brain cancer

NCCN publishes new easy-to-understand patient education resources focused on brain cancer

The National Comprehensive Cancer Network has published the NCCN Guidelines for Patients and NCCN Quick Guide sheets for Brain Cancer - Gliomas—the first in a series of patient education resources focused on Brain Cancer. [More]
New research suggests novel combination approach to fight against gliomas

New research suggests novel combination approach to fight against gliomas

"Devastating" and "dismal." That's how leading researchers describe the present outlook for malignant brain tumors. The median survival rate for patients with glioblastoma multiforme, or GBM, is a mere 14.2 months. [More]
Researchers identify attractive drug candidate to target glioma tumors

Researchers identify attractive drug candidate to target glioma tumors

In a paper published today in Cancer Research, researchers: 1) identify a biomarker enzyme associated with aggressive glioma brain tumors, 2) reveal the regulatory mechanism for that enzyme, and 3) demonstrate potent efficacy, using a mouse model of glioma, for a small molecule inhibitor they have developed. [More]
Scientists discover new biomarker to help determine aggressiveness of brain cancer

Scientists discover new biomarker to help determine aggressiveness of brain cancer

Researchers at UT Southwestern Medical Center have found a new biomarker for glioma, a common type of brain cancer, that can help doctors determine how aggressive a cancer is and that could eventually help determine the best course of treatment. [More]
Ancient Japanese art inspires groundbreaking technique to create ‘artificial brains’

Ancient Japanese art inspires groundbreaking technique to create ‘artificial brains’

The ancient Japanese art of flower arranging was the inspiration for a groundbreaking technique to create tiny "artificial brains" that could be used to develop personalized cancer treatments. [More]
Tumour cell of origin in childhood malignant glioma impacts susceptibility to cancer therapy

Tumour cell of origin in childhood malignant glioma impacts susceptibility to cancer therapy

Children that are diagnosed with the severe the brain tumour malignant glioma often have a very poor prognosis. Knowledge about how pediatric malignant glioma arises and develops is still limited. [More]
Researchers identify pathway that helps cancer cells to aggressively spread in the brain

Researchers identify pathway that helps cancer cells to aggressively spread in the brain

Glioblastoma multiforme remains the most common and highly lethal brain cancer and is known for its ability to relapse. [More]
Experimental cancer imaging tool shows promise in illuminating brain tumors during surgery

Experimental cancer imaging tool shows promise in illuminating brain tumors during surgery

An experimental cancer imaging tool that makes tumors glow brightly during surgery has shown promise again in a new Penn Medicine clinical study, this time in patients with brain cancer. [More]
Deficiency of tumor suppressor gene may allow brain cancer cells to survive outside niches

Deficiency of tumor suppressor gene may allow brain cancer cells to survive outside niches

Astronauts survive in space by wearing high-tech space suits. But how do brain cancer cells thrive when they migrate to inhospitable sites within the brain? [More]
Consortium develops new approach to understand causes of common cancers

Consortium develops new approach to understand causes of common cancers

Through the development of a novel, inexpensive genotyping microarray, the OncoArray, Dartmouth investigators have led a key collaborative research study that will revolutionize our knowledge of the causes of common cancers. [More]
Researchers develop MRI-based method that can track progression of genetically mutated gliomas

Researchers develop MRI-based method that can track progression of genetically mutated gliomas

UT Southwestern Medical Center researchers have developed an MRI-based method that can track the state and progression of a common type of genetically mutated brain cancer. [More]
Researchers report high response rate with single drug in phase I/II trial of paediatric brain cancer

Researchers report high response rate with single drug in phase I/II trial of paediatric brain cancer

A high response rate with a single drug in a phase I/II trial of paediatric brain tumour has set the stage for combination therapy with higher response and lower toxicity, researchers reported at the ESMO 2016 Congress in Copenhagen. [More]
Study identifies prognostic value of IDH and CIC mutations for grade II/III glioma patients

Study identifies prognostic value of IDH and CIC mutations for grade II/III glioma patients

NRG Oncology investigators have identified two biomarkers that are prognostic of overall and progression-free survival for patients with lower-grade gliomas. [More]
University education linked to higher risk of brain tumor

University education linked to higher risk of brain tumor

Men and women with a university degree are more prone to developing a brain tumor than people who do not take up higher education, according to an observational study published in the Journal of Epidemiology & Community Health. [More]
UCLA scientists develop statistical method for conducting survival analysis of cancer patients

UCLA scientists develop statistical method for conducting survival analysis of cancer patients

People with cancer are often told by their doctors approximately how long they have to live, and how well they will respond to treatments, but what if there were a way to improve the accuracy of doctors' predictions? [More]
Giving chemotherapy after radiotherapy delays rare brain tumour growth

Giving chemotherapy after radiotherapy delays rare brain tumour growth

GIVING chemotherapy after radiotherapy delays further growth of a rare type of brain tumour, increasing the number of patients alive at five years from 44 per cent to 56 per cent. [More]
Radiation therapy with bevacizumab/pembrolizumab improves outcomes in glioma patients

Radiation therapy with bevacizumab/pembrolizumab improves outcomes in glioma patients

Patients with recurrent high-grade glioma brain tumors have few effective treatment options and the majority of available therapies do not improve survival. Moffitt Cancer Center will present preliminary results from a phase 1 study testing whether the addition of pembrolizumab to radiation therapy and bevacizumab is safe and can control tumor growth for these patients. [More]
Specific immune system genes may determine how long people can live with glioblastoma

Specific immune system genes may determine how long people can live with glioblastoma

Researchers have identified a group of immune system genes that may play a role in how long people can live after developing a common type of brain cancer called glioblastoma multiforme, a tumor of the glial cells in the brain. [More]
Clinical trials of anti-cancer agent PAC-1 continue to progress with anonymous funding

Clinical trials of anti-cancer agent PAC-1 continue to progress with anonymous funding

Clinical trials of the anti-cancer agent PAC-1 are continuing to expand, thanks to a $7 million angel investment from an anonymous contributor who originally invested $4 million to help get the compound this far in the drug-approval pipeline. [More]
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