Glucagon News and Research

RSS

First clinical trial of GABA/GAD focused exclusively on children with recent onset Type 1 diabetes

For the first time, humans with newly diagnosed Type 1 diabetes, or T1D, have received two treatments called GABA and GAD that have shown promise in animal studies and in isolated human pancreas islets. This investigator-initiated clinical trial, published in Nature Communications, focused exclusively on children with recent onset T1D.

22 Feb 2023

Are SGLT2 inhibitors the next blockbuster drug?

Recent clinical trials investigating the therapeutic potency of sodium-glucose cotransporter 2 inhibitors (SGLT2i) have highlighted that this drug is highly effective in treating patients with cardiovascular and renal diseases.

19 Feb 2023

Study provides a rare view of real-world use of off-label drugs prescribed for Type 1 diabetes

Two classes of drugs prescribed off-label for some patients with Type 1 diabetes can provide significant benefits but also come with health concerns, according to a study by UT Southwestern Medical Center researchers.

16 Feb 2023

Preventing, diagnosing, and treating cardiovascular disease in women

An article published in the journal Medical Clinics of North America provides recent updates on cardiovascular disease prevention, diagnosis, and treatment in women.

8 Feb 2023

Gut hormone receptor polyagonists show promise for obesity and diabetes

A new paper in the Journal of Clinical Investigation describes drugs that could help lose weight and manage type 2 diabetes mellitus (T2DM).

6 Feb 2023

Genetically increasing omega-3 fatty acid production improves glucose balance in obese mice

A new study from researchers at Laval University in Quebec, Canada, shows that genetically increasing omega-3 fatty acid production, without direct gut microbiota contact, improves the balance of insulin and glucagon (glucose balance) in obese mice.

25 Jan 2023

New Clinical Practice Guideline offers recommendations to manage hypoglycemia in people with diabetes

People with diabetes are benefiting from advances in medications and technologies to lower their risk of hypoglycemia, according to a Clinical Practice Guideline issued today by the Endocrine Society.

7 Dec 2022

SARS-CoV-2 can cause hyperglycemia in cats

In a recent study published in The Journal of Infectious Diseases, researchers explored the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and hyperglycemia in cats.

30 Nov 2022

Almond consumption could keep extra kilos at bay, research says

Weight loss is never an easy nut to crack, but a handful of almonds could keep extra kilos at bay according to new research from the University of South Australia.

21 Nov 2022

Researchers explore the role of trigeminal axons in nose-to-brain delivery of antidepressant

Intranasal (in.) administration has been garnering increasing popularity as a non-invasive approach to deliver drugs directly to the brain. This approach involves the respiratory or olfactory epithelia of the nasal mucosa through which the drugs reach the central nervous system (CNS).

11 Nov 2022

Weekly weight loss drug reduces BMI in teens

Researchers report that a weekly dose of semaglutide led to a significant BMI reduction in adolescents.

3 Nov 2022

International group of honorees to provide latest insights into preventing and treating obesity

An international group of honorees have been selected to present innovative research designs providing the latest insights into preventing and treating obesity during the 10th annual Obesity Journal Symposium.

14 Oct 2022

Associations of cardioprotective medications with COVID-19 outcomes

Researchers evaluated COVID-19 outcomes in patients taking four types of cardioprotective medicines.

14 Oct 2022

Metformin reduces risk of severe COVID-19 in diabetic patients

A new study determines whether antidiabetic agents can reduce complications in COVID-19 patients with diabetes.

10 Oct 2022

Study establishes a direct link between disruption of circadian clocks and lipid changes in diabetics

A team from Geneva, Switzerland, shows that the disruption of lipid temporal profiles in type 2 diabetes stiffens the membrane of pancreatic endocrine cells, which could alter their function.

19 Sep 2022

Obese children who recently lost weight more likely to show hunger-related brain activity after a meal

Children with obesity, who have recently lost weight, are more likely to show hunger-related activity in their brains after a meal, according to research presented today at the 60th Annual European Society for Paediatric Endocrinology Meeting.

15 Sep 2022

Is there a right time for eating?

In a recent study published in the journal Cell Metabolism, researchers assessed how calorie or energy intake (EI) time influences calorie distribution and all energy expenditure (EE) components, which, in turn, impact energy balance and weight loss in healthy obese people.

12 Sep 2022

Researchers discover how patients with mutations in a DNA sequence develop pancreatic malformations

Researchers at the Centre for Genomic Regulation have identified a DNA sequence that is crucial for pancreatic differentiation and function – and for the first time – describe how it works.

22 Aug 2022

Novel member of a class of anti-diabetes drugs could help treat muscle wasting disease

Inflammatory myopathies can be challenging to treat, but a new study reports encouraging findings for patients with these debilitating conditions. Researchers from Japan have found that a novel member of a class of anti-diabetes drugs could be the key to treating patients with muscle wasting disease.

18 Aug 2022

Eating disorders could be treated by modulating gut microbiota

Researchers describe how the gut-brain axis facilitates communication between the gastrointestinal tract and brain to regulate food consumption behaviors.

17 Aug 2022