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Glucocorticoid is a compound that belongs to the family of compounds called corticosteroids (steroids). Glucocorticoids affect metabolism and have anti-inflammatory and immunosuppressive effects. They may be naturally produced (hormones) or synthetic (drugs).

Financial results for third-quarter 2009 announced by Combinatorx

3. November 2009 08:47
CombinatoRx, Incorporated today reported financial results for the third quarter ended September 30, 2009. [More]

Posted in: Business / Finance

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Steroid-induced osteoporosis can now be treated with Teriparatide

29. October 2009 02:10
A recent study determined glucocorticoid-induced osteoporosis (OP) is now treatable with Teriparatide, a synthetic form of the human parathyroid hormone. Researchers found patients with glucocorticoid-induced OP who were treated with teriparatide for 36 months had a greater increase in bone mineral density (BMD) and fewer new vertebral fractures than those treated with alendronate. [More]

Posted in: Medical Condition News | Pharmaceutical News

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CombinatoRx announces Synavive Phase 2 extension trial results at the 2009 ACR meeting

21. October 2009 08:18
CombinatoRx, Incorporated today announced the results of a 12 month knee osteoarthritis (OA) Phase 2 extension trial for Synavive™ (CRx-102) at the American College of Rheumatology (ACR) 2009 Annual Meeting in Philadelphia. The data demonstrated that Synavive-treated subjects maintained efficacy levels throughout the 12 month extension trial. [More]

Posted in: Drug Trial News | Medical Condition News

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SwitchGear Genomics introduces high-throughput research tools for profiling biological pathway regulation

14. October 2009 08:41
SwitchGear Genomics, Inc., a leading provider of products for studying regulatory elements in the human genome, today announced the availability of the first cost-effective, high-throughput research tools for screening transcriptional activation and repression in a number of key biological pathways. [More]

Posted in: Device / Technology News | Medical Science News

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CombinatoRx' Prednisolone/Dipyridamole Combination abstract to be presented at the ACR 2009

8. October 2009 08:18
CombinatoRx, Incorporated today announced that its abstract entitled, “CRx-102 (Prednisolone/Dipyridamole Combination) Enhances Glucocorticoid (GC) Efficacy and Reduces Adverse Effects in OA Therapy: 3-12 Month Results”, has been accepted for oral presentation at the American College of Rheumatology (ACR) 2009 Annual Meeting in Philadelphia on October 20, 2009. [More]

Posted in: Pharmaceutical News

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Researchers discover why smoking increases the risk of heart disease and stroke

2. September 2009 05:12
Researchers have discovered a reason why smoking greatly increases the risk of heart disease and stroke. Nicotine promotes insulin resistance, also called prediabetes, which is a risk factor for cardiovascular disease, according to the new study, which was presented at The Endocrine Society's 91st Annual Meeting in Washington, D.C. [More]

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Positive results from second pivotal phase III trial for Lodotra

2. September 2009 04:48
Nitec Pharma AG ("Nitec" or "Nitec Pharma"), a Switzerland-based specialty pharma company focused on the development and commercialization of medicines to treat chronic inflammation and pain-related diseases, today announced positive results from the second pivotal phase III trial for its lead product, Lodotra(TM). [More]

Posted in: Drug Trial News | Pharmaceutical News

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Steroid hormones found to affect gene activity

19. August 2009 21:58
Intermittent signaling by steroid hormones can affect the way genes are expressed in rodents, according to research by scientists at the University of Bristol and the National Cancer Institute (NCI), USA. This work has major implications for understanding how steroids work and opens novel avenues for new therapies. [More]

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Association of Specialty Professors announces the 2009 T. Franklin Williams scholars

10. August 2009 18:21
The Association of Specialty Professors (ASP) is pleased to announce the eighth class of T. Franklin Williams Scholars. These scholars are recipients of two- to four-year career development awards funded by a generous grant from the Atlantic Philanthropies (USA) Inc. and the John A. Hartford Foundation, and co-sponsored by 12 internal medicine specialty societies. [More]

Posted in: Miscellaneous News

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New findings on how stress causes sexual dysfunction and infertility

16. June 2009 02:49
University of California, Berkeley, researchers have found what they think is a critical and, until now, missing piece of the puzzle about how stress causes sexual dysfunction and infertility. [More]

Posted in: Medical Research News

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Appetite-stimulating hormone may protect muscle from atrophy

13. June 2009 20:50
Researchers have found a potential new treatment for the common problem of muscle atrophy. Results of the animal study were presented at The Endocrine Society's 91st Annual Meeting in Washington, D.C. [More]

Posted in: Medical Research News

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Nicotine promotes insulin resistance

13. June 2009 20:35
Researchers have discovered a reason why smoking greatly increases the risk of heart disease and stroke. Nicotine promotes insulin resistance, also called prediabetes, which is a risk factor for cardiovascular disease, according to the new study, which was presented at The Endocrine Society's 91st Annual Meeting in Washington, D.C. [More]

Posted in: Medical Research News

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Inflammation clue to fragile bones in Duchenne's muscular dystrophy

25. May 2009 19:10
Inflammation could contribute to bone loss in Duchenne's muscular dystrophy (DMD), a discovery made by a group of Italian researchers. Dr Anna Rufo and her colleagues found that levels of an inflammatory molecule, known as IL-6, are high in patients with DMD. [More]

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Arsenic exposure linked to influenza A (H1N1) susceptibility

20. May 2009 15:09
This colorized negative stained transmission electron micrograph (TEM) depicts some of the ultrastructural morphology of the A/CA/4/09 swine flu virus. Credit: CDC/C. S. Goldsmith and A. Balish The ability to mount an immune response to influenza A (H1N1) infection is significantly compromised by a low level of arsenic exposure that commonly occurs through drinking contaminated well water, scientists at the Marine Biological Laboratory (MBL) and Dartmouth Medical School have found. [More]

Posted in: Disease/Infection News

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Engineered antibody gives cancer the recognition it deserves

22. April 2009 21:10
In concept, the human immune system has the power to destroy cancer cells with great specificity. [More]

Posted in: Medical Research News

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