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Glutamine is an amino acid used in nutrition therapy. It is also being studied for the treatment of diarrhea caused by radiation therapy to the pelvis.
Nutrition and breast cancer; starving triple negative breast cancer cells to death: an interview with Associate Professor Jeff Holst

Nutrition and breast cancer; starving triple negative breast cancer cells to death: an interview with Associate Professor Jeff Holst

While there are a range of reports that different foods and food groups can increase or decrease your risk of cancer, these associations are very difficult to scientifically verify. [More]
Study reveals mechanism behind protein-related diseases

Study reveals mechanism behind protein-related diseases

Dartmouth researchers have found that some proteins turn into liquid droplets on the way to becoming toxic solids implicated in neurodegenerative diseases and other genetic disorders. [More]
Scientists find new way to inhibit growth of lung cancer cells

Scientists find new way to inhibit growth of lung cancer cells

Scientists have identified a new way to stop the growth of lung cancer cells, by blocking their ability to use alternative sources of nutrition. The discovery was made possible by identifying the metabolic programs used by cancer cells to fuel their growth. [More]
Researchers find significant link between breast cancer and nutrition, explore new preventative treatment

Researchers find significant link between breast cancer and nutrition, explore new preventative treatment

Researchers at Sydney’s Centenary Institute are working on a new treatment aimed at “starving” breast cancer cells, following the discovery of a significant link between breast cancer and nutrition. [More]
UH researcher investigates two new avenues for detection, treatment of prostate cancer

UH researcher investigates two new avenues for detection, treatment of prostate cancer

Prostate cancer is the most commonly diagnosed malignancy and second leading cause of cancer-related deaths among men in the U.S. The challenge with prostate cancer is that the standard treatment methods in the advanced stage of the disease lose effectiveness after about one to two years, leading to recurrence and, ultimately, death. A University of Houston researcher and his team are working to change that. [More]
Cancer-causing gene disrupts internal rhythm, metabolic pathways in cancer cells

Cancer-causing gene disrupts internal rhythm, metabolic pathways in cancer cells

Myc is a cancer-causing gene responsible for disrupting the normal 24-hour internal rhythm and metabolic pathways in cancer cells, found a team led by researchers from the Perelman School of Medicine at the University of Pennsylvania. Postdoctoral fellow Brian Altman, PhD, and doctoral student Annie Hsieh, MD, both from the lab of senior author Chi Van Dang, MD, PhD, director Abramson Cancer Center, study body clock proteins associated with cancer cells. [More]
Cognizin citicoline shows promise in patients with bipolar disorder and cocaine dependence

Cognizin citicoline shows promise in patients with bipolar disorder and cocaine dependence

The results of a randomized, double-blind, placebo-controlled clinical trial showed that Cognizin citicoline (Jarrow Formulas) was effective at reducing cocaine use, based on urine drug screens, in patients with bipolar disorder and cocaine dependence. The study, published in the American Journal of Psychiatry in Advance, included a total of 130 outpatients with bipolar I disorder and cocaine dependence, who received either Cognizin citicoline or placebo add-on therapy for 12 weeks. [More]
New research could help reverse side effects of acetaminophen overdose

New research could help reverse side effects of acetaminophen overdose

New research could help reverse deadly side effects caused by excessive doses of the drug acetaminophen, the major ingredient in Tylenol and many other over-the-counter and prescription medicines. [More]
Ruhr-Universität Bochum scientists develop mouse model to investigate SCA6

Ruhr-Universität Bochum scientists develop mouse model to investigate SCA6

Scientists at the Ruhr-Universität Bochum established a mouse model for the human disease SCA6. SCA6 is characterised by movement deficits and caused by similar genetic alterations as Chorea Huntington. The mouse model will be used to investigate the disease mechanisms. [More]
Study examines effects of intravenous glutamine on hind limb ischemia reperfusion injury

Study examines effects of intravenous glutamine on hind limb ischemia reperfusion injury

A single dose of intravenous glutamine (GLN) administered immediately after a non-lethal lower limb ischemia reduces the reperfusion inflammatory reaction locally and systemically according to a new study. [More]
Researchers submit patent application for drug that could destroy acute lymphoblastic leukemia

Researchers submit patent application for drug that could destroy acute lymphoblastic leukemia

A patent application for a drug that could destroy the deadly childhood disease known as acute lymphoblastic leukemia — and potentially other cancers as well — has been submitted by researchers at Sandia National Laboratories, the University of Maryland and the MD Anderson Cancer Center in Houston. [More]
Allele-specific lncRNA regulates cancer metabolism

Allele-specific lncRNA regulates cancer metabolism

Long non-coding RNAs (lncRNA) are unusual in that they don't encode proteins like normal RNA. Yet they do play a role in regulating cellular functions and interest cancer researchers. [More]
Study: Broken communication in brain regions appears to worsen Huntington's disease

Study: Broken communication in brain regions appears to worsen Huntington's disease

Indiana University researchers have found that broken communication in a specific part of the brain plays a role in the involuntary physical movements that affect individuals with Huntington's disease. [More]
Emmaus Life Sciences presents Phase 3 clinical trial of PGLG treatment for sickle cell disease

Emmaus Life Sciences presents Phase 3 clinical trial of PGLG treatment for sickle cell disease

Emmaus Life Sciences, Inc., a biopharmaceutical company dedicated primarily to the discovery, development and commercialization of innovative treatments and therapies for rare and orphan diseases today announced that data from the Company’s Phase 3 clinical trial of its pharmaceutical grade L-glutamine (PGLG) treatment for sickle cell anemia and sickle beta-0 thalassemia, will be presented, during the 9th Annual Sickle Cell Disease Research and Educational Symposium and 38th National Sickle Cell Disease Scientific Meeting. [More]
Researchers discover new metabolic mechanisms linked to macrophage polarization

Researchers discover new metabolic mechanisms linked to macrophage polarization

A group of researchers from Washington University in St. Louis, Agios Pharmaceuticals and ITMO University has discovered new metabolic mechanisms that regulate macrophage polarization - the unique ability of these immune cells to change their specialization depending on the required task. [More]
Metabolic derangement may facilitate cell proliferation in PAH

Metabolic derangement may facilitate cell proliferation in PAH

An enzyme that facilitates modification of proteins via a glucose metabolism pathway may promote cell proliferation in the lung tissue of patients with idiopathic pulmonary arterial hypertension, say researchers. [More]
BeiGene chooses SAFC's CHOZN Platform to support oncology drug development

BeiGene chooses SAFC's CHOZN Platform to support oncology drug development

Sigma-Aldrich Corporation today announced that SAFC Commercial, its custom manufacturing services business unit, has entered a commercial sales and service contract with leading biopharmaceutical company, BeiGene. [More]
Xylem’s YSI biochemistry analyzer is effective tool for cell culture and cancer research

Xylem’s YSI biochemistry analyzer is effective tool for cell culture and cancer research

Specifically for oncology drug development applications, the YSI 2950 biochemistry analyzer is used to measure analytes such as glucose, glutamine, glutamate, lactate, providing a simple, automated analysis of bioprocess cell culture samples, with accurate results in less than a minute. [More]
Sanford-Burnham researchers discover control mechanism for glutamine uptake in breast cancer cells

Sanford-Burnham researchers discover control mechanism for glutamine uptake in breast cancer cells

Researchers at Sanford-Burnham Medical Research Institute have discovered a mechanism that explains why some breast cancer tumors respond to specific chemotherapies and others do not. The findings highlight the level of glutamine, an essential nutrient for cancer development, as a determinant of breast cancer response to select anticancer therapies, and identify a marker associated with glutamine uptake, for potential prognosis and stratification of breast cancer therapy. [More]
New study may lead to novel drug target for treating lung cancer

New study may lead to novel drug target for treating lung cancer

A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a key enzyme and its associated metabolic programming may lead to novel drug development to treat lung cancer. [More]
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