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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.
Digoxin drug increases risk of adverse cardiovascular events or sudden death

Digoxin drug increases risk of adverse cardiovascular events or sudden death

Digoxin may increase the risk of death in patients with atrial fibrillation (AF) by approximately 20%, according to results from the ROCKET AF trial presented at ESC Congress today by Dr Manesh Patel, director of interventional cardiology and catheterisation labs at Duke University Health System in Durham, North Carolina, US. [More]
Simple awareness campaign in general practice helps improve early diagnosis of AF

Simple awareness campaign in general practice helps improve early diagnosis of AF

A simple awareness campaign in general practice identifies new cases of atrial fibrillation (AF), according to research presented at ESC Congress today by Professor Jean-Marc Davy from France. [More]
Permanent atrial fibrillation twins risk of stroke than paroxysmal AF

Permanent atrial fibrillation twins risk of stroke than paroxysmal AF

Permanent atrial fibrillation (AF) doubles the risk of stroke compared to paroxysmal AF, according to research in more than 6 000 patients presented at ESC Congress today by Dr Thomas Vanassche from Belgium. The findings suggest that a simple clinical assessment of the type of AF can help doctors to better estimate stroke risk. [More]
‘Concerning’ rise in pneumococcus risk factors

‘Concerning’ rise in pneumococcus risk factors

Researchers report that the incidence of Streptococcus pneumoniae infection has fallen significantly in the USA in the past decade but describe a “concerning trend” whereby the baseline health status of those with serious pneumococcal disease has worsened. [More]
Experimental agent TRO40303 ineffective in patients with heart attack

Experimental agent TRO40303 ineffective in patients with heart attack

The administration of an experimental agent known as TRO40303 to patients who have had a heart attack, with the hope of preventing tissue damage when impaired blood flow is corrected (reperfusion), was disappointingly ineffective according to results of a European study of patients with acute ST-elevation myocardial infarction (STEMI) presented today as a Hot Line the ESC Congress 2014 with simultaneous publication in the European Heart Journal. [More]
Serelaxin reduces occurrence of in-hospital worsening heart failure

Serelaxin reduces occurrence of in-hospital worsening heart failure

Serelaxin reduces the occurrence of in-hospital worsening heart failure by almost half in patients admitted for acute heart failure, according to the RELAX-AHF trial. The results were presented for the first time today at ESC Congress by co-principal investigator Professor John R. Teerlink. [More]
'Good' cholesterol turns 'bad' by sugar-derived substance

'Good' cholesterol turns 'bad' by sugar-derived substance

Scientists at the University of Warwick have discovered that 'good' cholesterol is turned 'bad' by a sugar-derived substance. [More]
Morbidity, mortality of AF patients remains high at 1 year even with good use of oral anticoagulants

Morbidity, mortality of AF patients remains high at 1 year even with good use of oral anticoagulants

Mortality and morbidity of atrial fibrillation (AF) patients remains high at one year despite good use of oral anticoagulants, according to the one year follow up of the Atrial Fibrillation General Pilot Registry. [More]
Complete revascularisation leads to better outcomes in patients with heart attack

Complete revascularisation leads to better outcomes in patients with heart attack

In patients being treated for heart attack, complete revascularisation of all significantly blocked arteries leads to better outcomes compared to a strategy of unblocking just the "culprit" artery responsible for the heart attack, according to a new study presented today at ESC Congress 2014. [More]
Antihypertensive therapy decreases risk of mortality, CV events, strokes in older adults

Antihypertensive therapy decreases risk of mortality, CV events, strokes in older adults

Antihypertensive therapy reduces the risk of cardiovascular (CV) events, strokes and mortality in hypertensive older adults, according to research presented at ESC Congress 2014 today by Dr Maciej Ostrowski from Poland. [More]
Novel document on ventricular arrhythmias published in EP Europace

Novel document on ventricular arrhythmias published in EP Europace

The first expert consensus on ventricular arrhythmias is published today. The novel document compiles current evidence on the diagnosis and management of ventricular arrhythmias and was agreed by international experts from three continents. [More]
Intravenous iron supplement can improve quality of life for iron deficient heart failure patients

Intravenous iron supplement can improve quality of life for iron deficient heart failure patients

Heart failure patients with iron deficiency can experience significant and sustainable improvements in functional capacity and quality of life as well as reduced risk of hospital admission for worsening heart failure by receiving just one to two intravenous doses of an iron supplement, according to the results of a study presented today at ESC Congress 2014. [More]
Investigational LCZ696 drug: A real breakthrough for patients with heart failure

Investigational LCZ696 drug: A real breakthrough for patients with heart failure

An investigational new heart failure drug could be poised to change the face of cardiology based on Hot Line results presented today at ESC Congress 2014. [More]
Internal production of hydrogen peroxide can lead cells to exit cell cycle and become senescent

Internal production of hydrogen peroxide can lead cells to exit cell cycle and become senescent

What happens inside cells when they detect the activation of a cancer-inducing gene? Sometimes, cells are able to signal internally to stop the cell cycle. Such cells are able to enter, at least for a time, a protective non-growth state. [More]
Initiatives to reduce deaths from heart failure for patients worldwide

Initiatives to reduce deaths from heart failure for patients worldwide

The Heart Failure Association (HFA) of the European Society of Cardiology (ESC) is calling for global policy change relating to heart failure. An international white paper, Heart failure: preventing disease and death worldwide, was published in May 2014. [More]
ACCA Clinical Decision-Making Toolkit mobile app helps make quick and correct decision

ACCA Clinical Decision-Making Toolkit mobile app helps make quick and correct decision

The ACCA Clinical Decision-Making Toolkit mobile app is now available on the App Store and Google Play. When dealing with acute cardiovascular diseases, a few seconds can make the difference and instant access to the best recommendations can save lives. [More]
Janssen, Bayer announce expansion of EXPLORER global cardiovascular research program for XARELTO

Janssen, Bayer announce expansion of EXPLORER global cardiovascular research program for XARELTO

Janssen Research & Development, LLC and its development partner, Bayer HealthCare, announced today the expansion of the EXPLORER global cardiovascular research program for XARELTO (rivaroxaban) to include additional high-risk patient populations. [More]
Philips to highlight full range of cardiology solutions at ESC Congress 2014

Philips to highlight full range of cardiology solutions at ESC Congress 2014

Royal Philips today announced its presence at the European Society of Cardiology Congress 2014, where the company is highlighting the full range of its cardiology solutions serving clinicians and patients across the care continuum from prevention and diagnosis, to treatment, recovery and wellness. [More]
Viewpoints: Medicare no longer 'busting' the budget; a 'nightmare' trying to get coverage in D.C.

Viewpoints: Medicare no longer 'busting' the budget; a 'nightmare' trying to get coverage in D.C.

You're looking at the biggest story involving the federal budget and a crucial one for the future of the American economy. Every year for the last six years in a row, the Congressional Budget Office has reduced its estimate for how much the federal government will need to spend on Medicare in coming years. [More]
Amgen seeks FDA approval for evolocumab to treat patients with high cholesterol

Amgen seeks FDA approval for evolocumab to treat patients with high cholesterol

Amgen today announced the submission of a Biologics License Application (BLA) to the U.S. Food and Drug Administration for evolocumab seeking approval for the treatment of high cholesterol. [More]