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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.
Amgen announces submission of supplemental New Drug Application to FDA for Kyprolis (carfilzomib)

Amgen announces submission of supplemental New Drug Application to FDA for Kyprolis (carfilzomib)

Amgen today announced the submission of a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration for Kyprolis (carfilzomib) for Injection to seek an expanded indication for the treatment of patients with a form of blood cancer, relapsed multiple myeloma, who have received at least one prior therapy. [More]
Six hot line sessions set to reveal latest research in cardiovascular disease at ESC Congress 2015

Six hot line sessions set to reveal latest research in cardiovascular disease at ESC Congress 2015

Six hot line sessions at ESC Congress 2015 are set to reveal the latest in cardiovascular disease research across a range of conditions and comorbidities. Hot topics include atrial fibrillation, pacing, acute myocardial infarction, heart failure, hypertension, diabetes mellitus, pharmacology and coronary artery disease. [More]
UC San Diego researchers receive NIH grant to test efficacy of Sanofi's pain drug in treating Chagas disease

UC San Diego researchers receive NIH grant to test efficacy of Sanofi's pain drug in treating Chagas disease

The National Center for Advancing Translational Sciences, part of the National Institutes of Health (NIH), has awarded James McKerrow, MD, PhD, director of the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences, with a 2015 New Therapeutic Uses Award. [More]
ICER’s drug assessment program to provide trusted source of information about new drugs

ICER’s drug assessment program to provide trusted source of information about new drugs

With drug prices for cancer and many other conditions soaring to new highs amid questions about their true value to patients, the Institute for Clinical and Economic Review today launched a program to transform the way new drugs are evaluated and priced in the United States. [More]
HeartWare announces initiation of MVAD System CE Mark international clinical trial

HeartWare announces initiation of MVAD System CE Mark international clinical trial

HeartWare International, Inc., a leading innovator of less invasive, miniaturized circulatory support technologies that are revolutionizing the treatment of advanced heart failure, today announced commencement of its MVAD System CE Mark international clinical trial. [More]
New issue of FMCH Journal examines evidence-based population health and patient care

New issue of FMCH Journal examines evidence-based population health and patient care

Evidence-Based Approaches to Population Health and Family Practice is the theme of the new issue of Family Medicine and Community Health, an international peer reviewed medical journal with editorial offices in China and the U.S. The Summer 2015 issue includes six original research articles, two educational research articles and two systematic reviews addressing various topics in evidence based population health and patient care. [More]
No significant research undertaken to prevent or treat PPCM in healthy pregnant women, study reveals

No significant research undertaken to prevent or treat PPCM in healthy pregnant women, study reveals

Peripartum cardiomyopathy (PPCM) is a rare disorder characterized by weakened pumping of the heart, or "left ventricular dysfunction," which results in otherwise healthy pregnant women experiencing heart failure shortly before or up to five months after they deliver healthy babies. Despite the seriousness of this condition, a new study published in the Canadian Journal of Cardiology revealed that no significant research has been undertaken to explore how to prevent or treat this disorder. [More]
New drug patiromer could improve potassium levels of patients with diabetic kidney disease

New drug patiromer could improve potassium levels of patients with diabetic kidney disease

Among patients with diabetic kidney disease and hyperkalemia (elevated potassium levels in the blood), a potentially life-threatening condition, those who received the new drug patiromer, twice daily for four weeks, had significant decreases in potassium levels which lasted through one year, according to a study in the July 14 issue of JAMA. [More]
Lixiana (edoxaban) recommended for treating, preventing recurrent DVT and PE in adults

Lixiana (edoxaban) recommended for treating, preventing recurrent DVT and PE in adults

The National Institute for Health and Care Excellence has recommended a new treatment to help patients suffering from blood clots in the legs and lungs. [More]
Envarsus XR receives FDA approval for treatment of kidney transplant recipients

Envarsus XR receives FDA approval for treatment of kidney transplant recipients

Veloxis Pharmaceuticals A/S today announced U.S. Food and Drug Administration approval of Envarsus XR (tacrolimus extended-release tablets) for the prophylaxis of rejection in kidney transplant patients who require or desire conversion from other twice-daily tacrolimus products to once-daily Envarsus XR. [More]

University of Liverpool researchers discover common cause of cardiac injury in sepsis patients

Researchers at the University of Liverpool's Institute of Infection and Global Health (IGH) have discovered a common cause of heart damage in patients with sepsis. [More]
FDA approves new heart failure drug

FDA approves new heart failure drug

A new drug called Entresto has been approved by the U.S Food and Drug Administration (FDA) for the treatment of heart failure. [More]
Novartis announces FDA approval of Entresto to reduce risk of cardiovascular death, heart failure hospitalization

Novartis announces FDA approval of Entresto to reduce risk of cardiovascular death, heart failure hospitalization

Novartis announced today that the US Food and Drug Administration has approved Entresto™ tablets, previously known as LCZ696, to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure and reduced ejection fraction. [More]
Evidence-based initiative aims to prevent avoidable hospital readmissions

Evidence-based initiative aims to prevent avoidable hospital readmissions

A statewide effort led by key stakeholders in South Carolina successfully organized and implemented an evidence-based initiative aimed at improving the quality of healthcare transitions after hospital discharge to prevent avoidable readmissions. [More]
Sepsis readmissions have significant impact on health care expenditures in California

Sepsis readmissions have significant impact on health care expenditures in California

The Affordable Care Act created several national initiatives aimed at reducing hospital readmission rates for heart attacks, congestive heart failure and other common high-risk conditions. But there is still no national program intended to address sepsis, a potentially life-threatening illness caused by infection. [More]
New portable system can produce life-saving NO from air by means of electrical spark

New portable system can produce life-saving NO from air by means of electrical spark

Treatment with inhaled nitric oxide (NO) has proven to be life saving in newborns, children and adults with several dangerous conditions, but the availability of the treatment has been limited by the size, weight and complexity of equipment needed to administer the gas and the therapy's high price. [More]
New research suggests that Bcl-Rambo protein can protect against heart failure

New research suggests that Bcl-Rambo protein can protect against heart failure

A protein dubbed 'Bcl-Rambo' can protect against heart failure, suggests new research from King's College London and funded by the British Heart Foundation. [More]
UCLA patient successfully receives smaller Total Artificial Heart

UCLA patient successfully receives smaller Total Artificial Heart

A petite 44-year-old woman has received a successful heart transplant at Ronald Reagan UCLA Medical Center, thanks to an experimental Total Artificial Heart designed for smaller patients. [More]
Penn State Health, CHI complete transfer of St. Joseph Regional Health Network ownership

Penn State Health, CHI complete transfer of St. Joseph Regional Health Network ownership

Penn State Health and Catholic Health Initiatives have completed the transfer of ownership of CHI's affiliate, St. Joseph Regional Health Network (St. Joseph) in Reading, Pa., to Penn State Health. [More]
UCLA patient first in California to receive smaller Total Artificial Heart

UCLA patient first in California to receive smaller Total Artificial Heart

A petite 44-year-old woman has received a successful heart transplant at Ronald Reagan UCLA Medical Center, thanks to an experimental Total Artificial Heart designed for smaller patients. [More]
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