Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Inorganic nitrate reduces rate of heart dysfunction caused by doxorubicin

Virginia Commonwealth University researchers have found that nutrient supplementation, like the kind that is found in leafy greens, spinach and lettuce, may reduce the damage to the heart caused by a powerful anti-cancer drug.

20 May 2011

The Chartis Group and HPMG partner to help providers improve outpatient care delivery systems

HealthPartners Medical Group and Clinics and The Chartis Group today announce a unique collaboration to help hospitals and health systems achieve superior performance in health care quality and patient service, while simultaneously lowering costs.

20 May 2011

Isis receives $5M milestone payment from GSK for initiating ISIS-TTRRx Phase 1 study

Isis Pharmaceuticals, Inc. announced today that it has earned a $5 million milestone payment from GlaxoSmithKline related to the initiation of a Phase 1 clinical study for ISIS-TTRRx.

19 May 2011

Treadmill test helps predict lifetime risk of cardiovascular disease in middle-age people

In two separate studies, UT Southwestern Medical Center researchers have found that how fast a middle-age person can run a mile can help predict the risk of dying of heart attack or stroke decades later for men and could be an early indicator of cardiovascular disease for women.

19 May 2011

Aspirin, simvastatin not effective in combating pulmonary artery hypertension

Despite their beneficial effects in treating heart disease, neither aspirin nor simvastatin appear to offer benefit to patients suffering from pulmonary artery hypertension (PAH), according to a National Institutes of Health (NIH)-funded study conducted at four U.S. medical centers. This was the first NIH-funded randomized clinical trial (RCT) in PAH.

19 May 2011

Pfizer's axitinib Phase 3 trial in advanced renal cell carcinoma meets primary endpoints

Pfizer Inc. today announced data from the pivotal Phase 3 AXIS 1032 trial, showing that in patients with previously treated advanced renal cell carcinoma, axitinib significantly extended progression-free survival at the 47th Annual American Society of Clinical Oncology meeting in Chicago from June 3-7, 2011.

19 May 2011

Abiomed fiscal fourth quarter revenue increases 24% to $28.5 million

Abiomed, Inc., a leading provider of breakthrough heart support technologies, today reported fourth quarter fiscal 2011 revenue of $28.5 million, up 24% compared to revenue of $23.0 million in the same period of fiscal 2010.

18 May 2011

New book provides insight into new stem cell therapies for stabilizing heart function

A new book edited by researchers at Worcester Polytechnic Institute and the Stony Brook University School of Medicine provides a comprehensive look at the science and application of cellular therapies aimed at the leading cause of death---heart disease.

18 May 2011

Novel gene associated with heart development and aging process

Researchers at the University of Ottawa Heart Institute (UOHI) have identified a novel gene in the nucleus of muscle and brain cells that affects heart development and the aging process. Their investigation brings the promise of new treatments for an old, failing heart.

18 May 2011

Study offers new understanding of cell signaling networks tied to diabetes and cancer

Researchers at the University of Texas Medical Branch at Galveston and the University of California-San Diego School of Medicine have published a study that offers a new understanding of a protein critical to physiological processes involved in major diseases such as diabetes and cancer. This work could help scientists design drugs to battle these disorders.

18 May 2011

Adenotonsillectomy prevents high blood pressure and heart damage in children with OSA

Removing enlarged tonsils and adenoids may help prevent high blood pressure and heart damage in children who suffer from obstructive sleep apnea, according to a study conducted at Cincinnati Children's Hospital Medical Center.

17 May 2011

Journal of Burn Care & Research publishes Caldolor clinical study data in hospitalized patients

Cumberland Pharmaceuticals Inc. today announced that results from a clinical study evaluating the safety and efficacy of Caldolor Injection in treating fever and pain in hospitalized burn patients was published in Volume 32, Number 1 of the Journal of Burn Care & Research.

16 May 2011

Study finds link between heart failure hospitalization and readmission rates

Researchers compared hospitalization rates and rehospitalization rates of patients admitted for heart attack and for heart failure. Heart attack admissions are considered non-discretionary, whereas, heart failure admissions are considered more discretionary.

16 May 2011

Continuous positive airway pressure reduces cardiovascular mortality in elderly OSA patients

Continuous positive airway pressure (CPAP) effectively decreases the risk of cardiovascular death in elderly patients who suffer from obstructive sleep apnea (OSA), according to a study conducted by researchers in Spain.

16 May 2011

Loyola earns Joint Commission certification for heart pump therapy

Loyola University Hospital has been certified by the Joint Commission to begin implanting heart pumps known as left ventricular assist devices (LVADs) as permanent therapy for advanced heart failure.

16 May 2011

PROTECT II study data in high-risk percutaneous coronary intervention to be presented at EuroPCR

Abiomed Inc., a leading provider of breakthrough heart support technologies, today announced that data from the PROTECT II study will be presented by Jeffrey W. Moses, M.D., Director of Interventional Services at NewYork-Presbyterian Hospital/Columbia University - Cornell Medical Center, during the late-breaking registries and clinical trial update session at EuroPCR 2011 in Paris.

13 May 2011

59-year-old enrolls in study of stem cell transplantation during cardiac bypass

A 59-year-old Houston man became the first individual in the United States to enroll in a study using stem cell transplantation during cardiac bypass to treat severe heart failure.

12 May 2011

Researchers discover quarky calcium release in heart cells

Three years of microscopic experiments on heart cells has led to a discovery by a team of University of Maryland researchers and collaborators of the workings of faint calcium signals in the heart cells, a discovery that may translate into new therapies for heart disease.

12 May 2011

Response Biomedical first quarter total revenues increase 59% to $2,470,560

Response Biomedical Corporation reported financial results for the first quarter ended March 31, 2011. Total revenues for the three-month period ended March 31, 2011 increased 59% to $2,470,560 compared to $1,549,479 for the same period last year.

11 May 2011

Journal of Rheumatology publishes positive results from Cimzia Phase III trial in RA

UCB announced today results from a post hoc analysis of the RAPID 1 study published in the Journal of Rheumatology. The results suggest moderate to severe rheumatoid arthritis patients treated with Cimzia, the only approved PEGylated anti-TNF, together with methotrexate, achieved a rapid response associated with improved long-term outcomes one year after treatment began.

11 May 2011

Heart Failure News and Research

Further Reading

Inorganic nitrate reduces rate of heart dysfunction caused by doxorubicin

The Chartis Group and HPMG partner to help providers improve outpatient care delivery systems

Isis receives $5M milestone payment from GSK for initiating ISIS-TTRRx Phase 1 study

Treadmill test helps predict lifetime risk of cardiovascular disease in middle-age people

Aspirin, simvastatin not effective in combating pulmonary artery hypertension

Pfizer's axitinib Phase 3 trial in advanced renal cell carcinoma meets primary endpoints

Abiomed fiscal fourth quarter revenue increases 24% to $28.5 million

New book provides insight into new stem cell therapies for stabilizing heart function

Novel gene associated with heart development and aging process

Study offers new understanding of cell signaling networks tied to diabetes and cancer

Adenotonsillectomy prevents high blood pressure and heart damage in children with OSA

Journal of Burn Care & Research publishes Caldolor clinical study data in hospitalized patients

Study finds link between heart failure hospitalization and readmission rates

Continuous positive airway pressure reduces cardiovascular mortality in elderly OSA patients

Loyola earns Joint Commission certification for heart pump therapy

PROTECT II study data in high-risk percutaneous coronary intervention to be presented at EuroPCR

59-year-old enrolls in study of stem cell transplantation during cardiac bypass

Researchers discover quarky calcium release in heart cells

Response Biomedical first quarter total revenues increase 59% to $2,470,560

Journal of Rheumatology publishes positive results from Cimzia Phase III trial in RA

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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