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Hemophilia is a rare, inherited bleeding disorder in which your blood doesn’t clot normally. If you have hemophilia, you may bleed for a longer time than others after an injury. You also may bleed internally, especially in your knees, ankles, and elbows. This bleeding can damage your organs or tissues and, sometimes, be fatal.
TSRI biologists uncover new mechanism behind sense of touch

TSRI biologists uncover new mechanism behind sense of touch

Biologists on the Florida campus of The Scripps Research Institute have discovered a new mechanism that likely underlies how we feel force or touch. Their study suggests that "rafts" of fatty lipids on the cell surface act as compartments to keep certain enzymes from mixing with their binding partners. [More]
TSRI scientists develop new tool to uncover molecular details of protein structure

TSRI scientists develop new tool to uncover molecular details of protein structure

Scientists on the Florida campus of The Scripps Research Institute have developed a new tool for studying the molecular details of protein structure. [More]
New TSRI study sheds light on how the brain stores memories

New TSRI study sheds light on how the brain stores memories

A new study led by scientists at The Scripps Research Institute (TSRI) sheds light on how the brain stores memories. [More]
AAV-based gene therapy to treat liver disorders advances into human testing

AAV-based gene therapy to treat liver disorders advances into human testing

Liver-directed gene therapy delivered using adeno-associated viral (AAV) vectors to treat diseases such as hemophilia have advanced into human testing. [More]
TSRI scientists develop new approach for understanding diverse effects of endocrine-disruptors

TSRI scientists develop new approach for understanding diverse effects of endocrine-disruptors

Breast cancer researchers from the Florida campus of The Scripps Research Institute (TSRI) have developed a novel approach for identifying how chemicals in the environment--called environmental estrogens--can produce infertility, abnormal reproductive development, including "precocious puberty," and promote breast cancer. [More]
A new strategy to fight prostate cancer

A new strategy to fight prostate cancer

A new study led by scientists from the Florida campus of The Scripps Research Institute (TSRI) sheds light on a signaling circuit in cells that drives therapy resistance in prostate cancer. [More]
Researchers working to develop pill for inherited bleeding disorders

Researchers working to develop pill for inherited bleeding disorders

Motivated by the tribulations of hemophilia patients and their families, researchers funded by the National Institute of Biomedical Imaging and Bioengineering are working to develop a pill to treat this serious inherited bleeding disorder. [More]
TSRI scientists shed light on how antiviral drug stops influenza infections

TSRI scientists shed light on how antiviral drug stops influenza infections

A new study led by scientists at The Scripps Research Institute (TSRI) is the first to show exactly how the drug Arbidol stops influenza infections. The research reveals that Arbidol stops the virus from entering host cells by binding within a recessed pocket on the virus. [More]
TSRI scientist receives Outstanding Investigator Grant to focus on memory formation research

TSRI scientist receives Outstanding Investigator Grant to focus on memory formation research

Ron Davis, chair of the Department of Neuroscience on the Florida campus of The Scripps Research Institute has been awarded a $5 million Outstanding Investigator Grant, one of the first of its kind, by the National Institute of Neurological Disorders and Stroke of the National Institutes of Health. [More]
Hemophilia B patients produce near-normal levels of clotting factor IX after gene therapy, study shows

Hemophilia B patients produce near-normal levels of clotting factor IX after gene therapy, study shows

Researchers are reporting the highest and most sustained levels to date of the essential blood-clotting factor IX in patients with the inherited bleeding disorder hemophilia B. [More]
Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

CRISPR/Cas9, a powerful genome editing tool, is showing promise for efficient correction of disease-causing mutations. [More]
UT Austin researchers develop new oral capsule for treating hemophilia patients

UT Austin researchers develop new oral capsule for treating hemophilia patients

In the near future, hemophiliacs could be able to treat their disease by simply swallowing a capsule. [More]
ASGCT seeks to educate public and policy-makers on fundamentals of gene editing

ASGCT seeks to educate public and policy-makers on fundamentals of gene editing

On Nov. 21, 2016, the American Society of Gene & Cell Therapy released Therapeutic Gene Editing: an ASGCT White Paper, intended to provide policy-makers, patient advocates, and the interested public with the necessary background information in anticipation of an upcoming consensus report on human gene editing from the National Academy of Sciences and National Academy of Medicine (NAS), expected to be released in early 2017. [More]
TSRI scientists unravel mystery of ‘food coma’ phenomenon

TSRI scientists unravel mystery of ‘food coma’ phenomenon

Anyone who has drifted into a fuzzy-headed stupor after a large holiday meal is familiar with the condition commonly known as a "food coma." [More]
TSRI scientists offer novel structure-based drug design strategy for better breast cancer treatment

TSRI scientists offer novel structure-based drug design strategy for better breast cancer treatment

While there have been advances in the treatment of hormone-driven breast cancer, resistance to these therapies remains a significant problem. [More]
TSRI study reveals how circadian clocks may influence cancer growth

TSRI study reveals how circadian clocks may influence cancer growth

A new study led by scientists at The Scripps Research Institute describes an unexpected role for proteins involved with our daily "circadian" clocks in influencing cancer growth. [More]
TSRI study unravels how protein is directly responsible for sensing touch

TSRI study unravels how protein is directly responsible for sensing touch

A new study led by scientists at The Scripps Research Institute reveals that a protein first discovered at TSRI in 2010 is directly responsible for sensing touch. [More]
New European study emphasizes need to enhance standard of haemophilia care in real life

New European study emphasizes need to enhance standard of haemophilia care in real life

Swedish Orphan Biovitrum AB (publ) announces the results from a new European study that assessed the efficacy of haemophilia care in real life. [More]
TSRI study suggests new approach to limit tumor growth by targeting immune system cells

TSRI study suggests new approach to limit tumor growth by targeting immune system cells

A new study led by scientists at The Scripps Research Institute suggests there may be a way to limit tumor growth by targeting immune system cells called macrophages. [More]
TSRI scientists receive NIH grants for computational biology research

TSRI scientists receive NIH grants for computational biology research

Three groups at The Scripps Research Institute have been awarded grants from the National Institutes of Health to develop methods for computational modeling and to apply them to cutting-edge systems in biology and health. [More]
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