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Phase II clinical trial evaluates the safety and efficacy of a Muse cell-based product in patients with ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of motor functions, which eventually leads to death within 5 years of its onset.

1 Feb 2024

Study: Up to 10% of dementia cases in veterans may be caused by liver disease

As many as 10% of older U.S. veterans diagnosed with dementia may suffer instead from reversible cognitive decline caused by advanced liver disease, according to an analysis from the Virginia Commonwealth University's School of Medicine and the Richmond VA Medical Center.

31 Jan 2024

Researchers detect genetic traces of hepatitis E viruses in wastewater

Researchers have identified genetic traces of hepatitis E viruses in almost 73 percent of wastewater samples from North-Rhine Westphalia.

31 Jan 2024

New DNA-based vaccine can induce strong antibody response against SARS-CoV-2

Using a virus-like delivery particle made from DNA, researchers from MIT and the Ragon Institute of MGH, MIT, and Harvard have created a vaccine that can induce a strong antibody response against SARS-CoV-2.

30 Jan 2024

3D-printed liver model paves way for new MASH treatments

Metabolic dysfunction- associated steatohepatitis, or MASH, is an inflammatory, liver-scarring disease that has reached epidemic proportions, with an estimated 1.5% to 6.5% of U.S. adults afflicted by the condition, and roughly 24% of adults having nonalcoholic fatty liver disease (NAFLD).

23 Jan 2024

Study provides valuable insights into the evolutionary dynamics of hepatitis E virus

A combination therapy with multiple drugs is more effective than just one active compound. To begin with, at least.

23 Jan 2024

Antiviral hope emerges as viruses linked to multiple myeloma

A few years ago, a patient was cured of multiple myeloma after being treated for hepatitis C, astounding researchers from the group led by Joaquín Martínez, from the H12O-CNIO Haematological Tumours Clinical Research Unit, a collaboration between the Hospital 12 de Octubre (H12O) and the National Cancer Research Centre (CNIO).

19 Jan 2024

Study reveals intestinal helminth infection diminishes T cell response to COVID-19 mRNA vaccine

Study investigates the impact of helminth infection on COVID-19 mRNA vaccine efficacy, revealing that while antibody responses remain largely unaffected, T-cell responses are significantly impaired, particularly against Omicron variants.

17 Jan 2024

Study explores intratumoral microbiota as a novel frontier in cancer research

Researchers review the role of intratumoral microbiota in cancer development, suggesting its potential in predicting and treating various cancers.

14 Jan 2024

Extended liver preservation technique shows promise for daytime transplants

Phase II clinical trial evaluates the safety and feasibility of prolonged DHOPE for extending human donor liver preservation to 20 hours, showing potential for facilitating daytime liver transplantation.

11 Jan 2024

Inhalable point-of-care urinary diagnostic platform for early lung cancer detection

Using a new technology developed at MIT, diagnosing lung cancer could become as easy as inhaling nanoparticle sensors and then taking a urine test that reveals whether a tumor is present.

5 Jan 2024

Exploring the global health challenge of hepatitis D

Review explores the global impact of the hepatitis D virus (HDV) on public health, detailing its transmission, clinical course, diagnosis, and treatment options.

2 Jan 2024

Simple mail trick doubles liver cancer screening rates for high-risk patients

Liver cancer screening among patients with cirrhosis almost doubled when they were mailed a signed order from their specialist, according to a new study from the Perelman School of Medicine at the University of Pennsylvania.

22 Dec 2023

R21/Matrix-M vaccine gets WHO green light for global rollout

The R21/Matrix-M™ malaria vaccine is one step closer to mass rollout, after officially receiving WHO prequalification status, making it eligible for procurement by United Nations agencies.

21 Dec 2023

Autopsy study provides new insights into yellow fever's impact on the heart

To fill gaps in knowledge of yellow fever (YF), a group of researchers in Brazil affiliated with the Department of Pathology at the University of São Paulo's Medical School (FM-USP), Hospital das Clínicas (HC, the hospital complex run by FM-USP), the Heart Institute (InCor, linked to HC) and Emílio Ribas Institute of Infectious Diseases (IIER) decided to study the pathogenesis of YF-associated heart injury.

19 Dec 2023

Study shows synergistic effects of genetic factors, binge drinking, and diabetes in alcohol-related cirrhosis

Researchers investigated associations between alcohol consumption behaviors, diabetes mellitus, genetic predispositions, and ARLD incidence in 312,59 active drinkers from the United Kingdom Biobank.

18 Dec 2023

$9M awarded to study HIV and substance use at intersection of vulnerable populations

The Institute of Human Virology (IHV) at the University of Maryland School of Medicine (UMSOM) received an annual award for $3 million funded by the NIH Office of AIDS Research.

15 Dec 2023

Research shows how the immune system keeps Herpes simplex virus at bay

Herpes simplex virus (HSV) is extremely common, affecting nearly two-thirds of the world's population, according to the World Health Organization.

14 Dec 2023

Infective endocarditis deaths spike among young adults, research shows

Death rates related to infective endocarditis declined in most adults across the U.S. within the last two decades, yet accelerated among young adults ages 25 to 44 years old, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

13 Dec 2023