High Throughput Sequencing News and Research

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Role of biochip advancements in next-generation sequencing

Biochips are essentially tiny laboratories designed to function inside living organisms, and they are driving next-generation DNA sequencing technologies.

26 Jun 2019

ChIP-seq kit maximizes chromatin-antibody binding and capture

Optimizing protein orientation for maximum chromatin-antibody binding and capture enables Chromatrap® ChIP-seq kits to offer market leading sensitivity.

From Chromatrap® - Porvair Sciences Ltd 19 Jun 2019

Bacteriophage can have a profound impact on the dynamics of gut microbiome, study finds

The gut microbiome is a complex, interconnected ecosystem of species. And, like any ecosystem, some organisms are predators and some are prey.

7 Jun 2019

New Chromatrap ChIP-seq kit performs chromatin immunoprecipitation with unparalleled sensitivity

Porvair Sciences announces version 2.0 of its Chromatrap® ChIP-seq kit - developed to perform chromatin immunoprecipitation with unparalleled sensitivity.

From Chromatrap® - Porvair Sciences Ltd 3 Apr 2019

Researchers call for industry standards to help improve high-throughput genomic sequencing

Researchers from the George Washington University, the U.S. Food and Drug Administration, and industry leaders published in PLOS Biology, describing a standardized communication method for researchers performing high-throughput sequencing called BioCompute.

31 Jan 2019

Big data opens door for characterizing immunity-related genome in Japanese population

Although different genes are distributed widely across chromosomes, many genes related to the immune system are clustered together on human chromosome 6, in a segment called the major histocompatibility complex (MHC) region.

29 Jan 2019

Scientists aim to find genetic causes of developmental abnormalities in the vagina and uterus

A percentage of females are born with a missing or underdeveloped vagina and uterus, and scientists are working to analyze the genes of hundreds of them to get a better idea about causes, improve genetic counseling and ideally treatment.

22 Jan 2019

White colonies on kimchi surface is not formed by molds but by yeasts, finds study

WiKim reported that the white colonies on the surface of kimchi is not formed by molds but by "yeasts" and that genomic data was acquired regarding the hygienic safety of the yeast strains.

27 Dec 2018

RNA sequencing offers novel insights into the microbiome

Researchers have come up with a revolutionary strategy for studying the activity of the gut microbiome – using high-throughput sequencing of tRNA.

17 Dec 2018

New findings highlight importance of inflammatory component in atherosclerosis pathogenesis

One of the main characteristics of atherosclerosis is the accumulation of lipids in the intimal layer of the arterial wall.

29 Oct 2018

Study finds typical mutations in offspring of radar soldiers

The offspring of radar soldiers exposed to high doses of radiation during their service experience more genetic alterations than families without radiation exposure.

5 Oct 2018

Expert proposes new model to generate automated updates of genetic test results

Maybe the genetic test report your doctor ordered says your DNA contains many “variants of unknown significance.” Currently, up to 70 percent of such reports are negative or inconclusive.

4 Oct 2018

UTA scientist to provide new insights on the role of 'jumping genes'

A biology researcher at The University of Texas at Arlington will be using the high-tech tools provided by the North Texas Genome Center to shed light on the role of 'jumping genes'.

14 Sep 2018

New technique harnesses 'natural barcodes' to facilitate better cell tracking

Each of us carries in our genomes about 10 million genetic variations called single nucleotide polymorphisms, which represent a difference of just one letter in the genetic code.

24 Apr 2018

Tissue-specific changes in gene expression can help predict time of death

International team of scientists led by Roderic Guigó at the Centre for Genomic Regulation in Barcelona showed that changes in gene expression in different tissues triggered by death can be used to predict the time of death of an individual.

13 Feb 2018

Illumina and Bio‑Rad introduce first next-generation sequencing solution for single-cell analysis

Illumina, Inc. and Bio‑Rad Laboratories, Inc. today announced the launch of the Illumina Bio-Rad Single-Cell Sequencing Solution at the J.P. Morgan Healthcare Conference, San Francisco.

26 Jul 2017

Antibiotic use during peripartum period linked to greater risk of inflammatory condition in offspring

A study by researchers at the University of Chicago Medicine shows that when mice that are genetically susceptible to developing inflammatory bowel disease (IBD) were given antibiotics during late pregnancy and the early nursing period, their offspring were more likely to develop an inflammatory condition of the colon that resembles human IBD.

11 Jul 2017

Study offers better understanding of progression of metastatic breast cancer

Researchers at the Jules Bordet Institute - Université libre de Bruxelles, VIB and KU Leuven published this 21 of April an important study offering a better understanding of the progression of breast cancer.

24 Apr 2017

Chromatrap publishes new article comparing efficiency, sensitivity of native and cross-linked ChIP-seq kits

Chromatrap has published a new article that describes a detailed genome wide comparison of native and crosslinked chromatin immunoprecipitation followed by next generation sequencing (ChIP-seq) using the company's patented solid state spin column technology.

From Chromatrap® - Porvair Sciences Ltd 24 Mar 2017

Equipment for single-cell genomics launched by Illumina and Bio-Rad

Illumina, Inc. and Bio-Rad Laboratories, Inc. today announced the launch of the Illumina® Bio-Rad® Single-Cell Sequencing Solution at the J.P. Morgan Healthcare Conference. The comprehensive solution is the first next-generation sequencing (NGS) workflow for single-cell analysis, providing researchers the ability to investigate the coordinated contribution of individual cells in tissue function, disease progression, and therapeutic response.

From Illumina, Inc. 12 Jan 2017