Horse News and Research

RSS

CytoDel successfully delivers neuronal antibody in animal models of botulism

CytoDel, Inc., a privately-held corporation, today announces the publication of preclinical data on the Company's lead product, Cyto-111, in the peer-reviewed journal, Science Translational Medicine. The complete text of the article titled, "Neuronal Delivery of Antibodies has Therapeutic Effects in Animal Models of Botulism," can be found here.

7 Jan 2021

New approach produces strong antidotal efficacy in treating lethal botulism in animals

Related to new research published in the January issue of Science Translational Medicine, Patrick McNutt, PhD, of the Wake Forest Institute for Regenerative Medicine, was part of the research team that demonstrated a new "Trojan horse" approach that produces strong antidotal efficacy in treating lethal botulism in mice, guinea pigs and rhesus macaque monkeys.

7 Jan 2021

Black women find healing (but sometimes racism, too) in the outdoors

It would be the last hike of the season, Jessica Newton had excitedly posted on her social media platforms.

6 Jan 2021

Microplastic particles find their way into living cells if exposed to natural aquatic environments

The environment is polluted by microplastics worldwide. The tiny particles enter food chains, and thereby the digestive systems of animals and humans; moreover, they can be inhaled. Instead of being excreted, small microplastics can be incorporated into the body tissue.

10 Dec 2020

Intermediate embryonic stem cell type could lead to advances in regenerative medicine

A team led by UT Southwestern has derived a new "intermediate" embryonic stem cell type from multiple species that can contribute to chimeras and create precursors to sperm and eggs in a culture dish.

4 Dec 2020

Trump’s lame-duck status leaves governors to wing it on COVID

Not long after the world learned that President Donald Trump had lost his reelection bid, states began issuing a new round of crackdowns and emergency declarations against the surging coronavirus.

20 Nov 2020

Scientists exploit 'trojan horse' feature in SARS-CoV-2 virus to create antivirals against COVID-19

Scientific analysis of a protein enzyme found in COVID-19 could lead to the development of new drugs to treat the virus, research led by Oxford Brookes University scientists has found.

20 Nov 2020

Developing a precision 'Trojan Horse' nanotherapy to treat breast cancer

With a nearly $2.6 million grant from the National Institutes of Health, Michigan State University researchers are using nanoscopic particles to turn the body's own cells into weapons that cancer won't see coming.

9 Oct 2020

Anti-N-protein IgG may predict severity of COVID-19

A recent study by researchers at the University of Miami, Miami VA Healthcare System and Express Gene and published on the preprint server medRxiv in September 2020 reports on the prognostic significance of the anti-N Immunoglobulin G (IgG) antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

28 Sep 2020

Researchers develop 'Trojan horse' approach to destroy cancer cells

Cancer cells are killed in lab experiments and tumour growth reduced in mice, using a new approach that turns a nanoparticle into a 'Trojan horse' that causes cancer cells to self-destruct, a research team at the Nanyang Technological University, Singapore (NTU Singapore) has found.

23 Sep 2020

Michigan sees increasing EEE cases

In the United States, the Michigan Department of Health and Human Services (MDHHS) urge people to stay indoors, especially after dusk. Health officials have confirmed 22 horse cases of Eastern Equine Encephalitis (EEE), and one suspected human case.

17 Sep 2020

Triple therapy increases response rates in patients with Severe Aplastic Anemia

The European Society for Blood and Marrow Transplantation (EBMT), Europe's collaborative peer network of professionals working in the field of stem cell transplantation and cellular therapy, announced today the results of the phase III RACE trial during EBMTs virtual 46th Annual Meeting. Preliminary data show that adding Eltrombopag to standard immunosuppressive treatment is safe and increases response rates in patients with Severe Aplastic Anaemia.

31 Aug 2020

Equine antibody preparation shows greater capacity to neutralize SARS-CoV-2 isolate than human convalescent plasma

A recent Brazilian study demonstrates that hyperimmune globulin formulations generated against the recombinant spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) provide significantly high antibody titer with highly neutralizing capacity. The study is currently available on the bioRxiv preprint server.

23 Aug 2020

New book series advances the development of pharmaceutical agents for treating neurological, CNS disorders

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders.

21 Aug 2020

Heart cell treatment can benefit patients, shows study

More than three years after a clinical trial was prematurely ended for failing to show progress in healing heart attack scars, a prominent peer-reviewed journal is publishing some surprising results showing that the heart cell treatment does benefit patients.

4 Aug 2020

Face masks do not lead to false sense of security, shows study

Existing limited evidence suggests that wearing face coverings to protect against COVID-19 does not lead to a false sense of security and is unlikely to increase the risk of infection through wearers foregoing other behaviours such as good hand hygiene, say researchers from the University of Cambridge and King's College London.

27 Jul 2020