Huntington’s Disease News and Research

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Huntington's disease may take effect much earlier in life than previously believed, study suggests

A new study published in the Proceedings of the National Academy of Sciences suggests that Huntington's disease may take effect much earlier in life than was previously believed, and that a new drug may be key in controlling the disease.

5 Sep 2018

Protein aggregation in neurons linked to gene regulation in Huntington's disease

Researchers at Lund University in Sweden have discovered a direct link between the protein aggregation in nerve cells that is typical for neurodegenerative diseases, and the regulation of gene expression in Huntington's disease.

21 Aug 2018

Scientists use new drug discovery system to target Huntington’s Disease

Scientists have used a new drug discovery system to specifically target phosphatases in Huntington's, which were previously thought to be undruggable.

27 Jul 2018

Scientists use new drug discovery system to target Huntington’s Disease

Scientists have used a new drug discovery system to specifically target phosphatases in Huntington's, which were previously thought to be undruggable.

27 Jul 2018

Scientists take important step to understand mechanisms that cause Huntington's disease

The neuroscientist Dr David Vilchez and his team at CECAD, the University of Cologne's Cluster of Excellence for Aging Research, have made an important step towards understanding the mechanisms that cause the neurodegenerative disorder Huntington's disease.

27 Jul 2018

New theory on Huntington's disease shows promise to open new avenues of drug development

McMaster University researchers have developed a new theory on Huntington's disease which is being welcomed for showing promise to open new avenues of drug development for the condition.

10 Jul 2018

Study unravels new piece of information in the Huntington’s disease puzzle

In a new study, researchers from the University of Copenhagen have discovered a hitherto unknown error in the transport of glutamine between astrocytes and neurons in the brain of mice with Huntington's disease.

21 Jun 2018

Scientists find overlap between causes of RA and Huntington’s disease

Using new analytic tools, researchers at University of California San Diego School of Medicine and the Icahn School of Medicine at Mount Sinai have decoded the epigenetic landscape for rheumatoid arthritis (RA), a common autoimmune disease that affects more than 1.3 million Americans.

15 May 2018

Key signaling protein in Huntington's disease found to have deleterious effects on heart function, shows study

Researchers investigating a key signaling protein in Huntington's disease describe deleterious effects on heart function, going beyond the disease's devastating neurological impact.

25 Apr 2018

Scientists use CRISPR tool to make multiple edits to DNA samples 'in vitro'

Scientists at Christiana Care Health System's Gene Editing Institute have developed a potentially breakthrough CRISPR gene-editing tool. It could allow researchers to take fragments of DNA extracted from human cells, put them into a test tube, and quickly and precisely engineer multiple changes to the genetic code, according to a new study published today in the CRISPR Journal.

20 Apr 2018

Scientists find link between over-accumulation of mitochondrial iron and Huntington's disease

Scientists at the University of Wyoming have found that mice engineered to have Huntington's disease (HD) have an over-accumulation of iron in their mitochondria.

11 Apr 2018

Researcher finds that shape of misfolded proteins may contribute to Alzheimer’s, Parkinson’s and Huntington’s disease

Alzheimer's, Parkinson's and Huntington's disease may have more in common than their effects on the functions of the brain and spinal cord. And finding that common thread could lead to a treatment that could work for all three.

2 Apr 2018

Adult-onset degenerative disease mechanism begins much earlier than previously thought

The disease mechanism for adult-onset progressive degenerative diseases begins much earlier than previously thought, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.

30 Mar 2018

C-Path and CHDI announce launch of Huntington's Disease Regulatory Science Consortium

The Critical Path Institute, together with CHDI Foundation, Inc., today announced the official launch of C-Path's Huntington's Disease Regulatory Science Consortium.

28 Mar 2018

Golgi stress signaling pathway found in cells with Huntington’s disease

Working with cells grown in the lab, Johns Hopkins researchers have identified a biochemical pathway that allows a structure within cells, called the Golgi apparatus, to combat stress caused by free radicals and oxidants.

8 Mar 2018

The effects of Huntington’s disease can be seen as early as conception, finds new study

In a breakthrough study, scientists at the Rockefeller University have observed the effects of Huntington’s disease in neurons as early as conception.

30 Jan 2018

Researchers uncover key protein that rescues progression of adult spinocerebellar ataxia

Spinocerebellar ataxia is a group of neurodegenerative diseases characterized by progressive incoordination of gait, and is often associated with poor coordination of hands, speech, and eye movements.

27 Jan 2018

Discovery of potential biomarker for Huntington's disease may help postpone disease onset

A new discovery of a potential biomarker for Huntington's disease (HD) could mean a more effective way of evaluating the effectiveness of treatments for this neurological disease.

2 Jan 2018

Newly discovered molecular chaperones may soon be part of therapies for Huntington's disease

Huntington's disease is a neurodegenerative disease. It is always fatal. The disease is caused by a defect in the Huntingtin gene. To this day, no therapy will put a stop to the insidious disintegration of brain cells.

12 Dec 2017

Huntington's disease drug clears initial hurdles - raising hopes

Huntington’s disease is a genetic disorder that affects the brain progressively and has no known cure till date. In a breakthrough, the first drug that can target and reduce the cause behind this dreaded disease has been found to be effective, safe and well tolerated in a human clinical trial that was conducted by UCL scientists.

11 Dec 2017

Huntington’s Disease News and Research

Huntington's disease may take effect much earlier in life than previously believed, study suggests

Protein aggregation in neurons linked to gene regulation in Huntington's disease

Scientists use new drug discovery system to target Huntington’s Disease

Scientists use new drug discovery system to target Huntington’s Disease

Scientists take important step to understand mechanisms that cause Huntington's disease

New theory on Huntington's disease shows promise to open new avenues of drug development

Study unravels new piece of information in the Huntington’s disease puzzle

Scientists find overlap between causes of RA and Huntington’s disease

Key signaling protein in Huntington's disease found to have deleterious effects on heart function, shows study

Scientists use CRISPR tool to make multiple edits to DNA samples 'in vitro'

Scientists find link between over-accumulation of mitochondrial iron and Huntington's disease

Researcher finds that shape of misfolded proteins may contribute to Alzheimer’s, Parkinson’s and Huntington’s disease

Adult-onset degenerative disease mechanism begins much earlier than previously thought

C-Path and CHDI announce launch of Huntington's Disease Regulatory Science Consortium

Golgi stress signaling pathway found in cells with Huntington’s disease

The effects of Huntington’s disease can be seen as early as conception, finds new study

Researchers uncover key protein that rescues progression of adult spinocerebellar ataxia

Discovery of potential biomarker for Huntington's disease may help postpone disease onset

Newly discovered molecular chaperones may soon be part of therapies for Huntington's disease

Huntington's disease drug clears initial hurdles - raising hopes

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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