Hybridization News and Research

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Shortage of specific gene 'silencing' molecules linked with pediatric low-grade gliomas

Experimenting with lab-grown brain cancer cells, Johns Hopkins Medicine researchers have added to evidence that a shortage of specific tiny molecules that silence certain genes is linked to the development and growth of pediatric brain tumors known as low-grade gliomas.

12 Nov 2018

Quantum dot-based FISH method enhances cell imaging

A team of researchers from the University of Illinois at Urbana-Champaign and Mayo Clinic have engineered a new type of molecular probe that can measure and count RNA in cells and tissue without organic dyes.

30 Oct 2018

Researchers now confirm that genome duplication drives evolution of species

Many wild and cultivated plants arise through the combination of two different species. The genome of these so-called polyploid species often consists of a quadruple set of chromosomes - a double set for each parental species - and thus has about twice as many genes as the original species.

25 Sep 2018

New study reveals surprising link between gut microbiota and skin allergies

Over the last few years, scientists have discovered connections between gut microbiota imbalances and various diseases.

25 Sep 2018

Study: Neural signal that urges to eat overpowers the one that says to stop

Almost everyone knows the feeling. You're at a restaurant or a holiday meal, and your stomach is telling you it's full, so logically you know you should stop eating.

21 Sep 2018

Scientists find wild African monkeys infected with bacterium that causes syphilis, yaws in humans

An international research team, led by scientists from the German Primate Center, the Robert Koch Institute, the Max Planck Institute for Evolutionary Anthropology, McGill University, Masaryk University, the University of Tübingen and the Max Planck Institute for the Science of Human History, has successfully recovered genomes of the bacterium Treponema pallidum, which causes syphilis and yaws in humans, from wild nonhuman primate populations across sub-Saharan Africa.

20 Sep 2018

Researchers develop fast detection strategy to know type of virus acquired by patients

Even tiny amounts of viruses can have disastrous consequences. RNA identification can reveal the type of virus present.

20 Sep 2018

Study finds overlapping copy number variations in Japanese patients with autism and schizophrenia

Common genetic variants may underlie autism spectrum disorder and schizophrenia across human populations, according to a study appearing September 11th in the journal Cell Reports.

12 Sep 2018

Individualized therapies targeting specific features show promise in transforming cancer treatment

Individualized therapies that target the specific genetic features of tumors have the potential to transform cancer diagnosis, treatment and care.

10 Sep 2018

New assay may help improve both sarcoma diagnosis and treatment

Sarcomas are rare tumors that are often misdiagnosed. Specific recurrent chromosomal rearrangements, known as translocations, can serve as essential diagnostic markers and are found in about 20 percent of sarcomas.

20 Aug 2018

OGT announces launch of updated SureSeq Interpret NGS analysis software

Oxford Gene Technology, The Molecular Genetics Company, has announced the launch of the eagerly-anticipated update to its SureSeq Interpret software, included with purchases of SureSeq NGS panels.

From Oxford Gene Technology 10 Aug 2018

Study finds false negatives in common tests used to determine ROS1 status in lung cancer

Drugs like crizotinib are used to treat patients with ROS1-positive lung cancer. But which patients are ROS1-positive? A University of Colorado Cancer Center study published in the Journal of Thoracic Oncology shows that common laboratory tests used to determine ROS1 status all have inherent limitations that can lead to false-negative results.

9 Aug 2018

OGT announces direct sales and support services in Europe

Oxford Gene Technology, The Molecular Genetics Company, has announced that it is now directly selling Cytocell Fluorescence In Situ Hybridisation products through several established affiliates of SysmexCorporation in Europe following its acquisition last year.

From Oxford Gene Technology 4 Jul 2018

OGT increases NGS cancer panel content to provide more flexibility for customization

Oxford Gene Technology, The Molecular Genetics Company, has expanded its SureSeq myPanel™ NGS Custom Cancer Panel content - now covering 120 fully optimized cancer related genes.

From Oxford Gene Technology 13 Jun 2018

New guideline for HER2 testing in breast cancer benefits patients and clinicians

Published today, a Focused Update to the American Society of Clinical Oncology/College of American Pathologists guideline for human epidermal growth factor receptor 2 (HER2) testing in breast cancer brings new levels of clarity that will benefit patients and clinical teams alike.

31 May 2018

Lunaphore and Vitro announce partnership to develop ISH protocols for RNA, DNA targets

Lunaphore Technologies SA, a next generation tissue diagnostics company, and Vitro SA, a manufacturer in the field of Pathology and Biomedical Research, announce today a collaboration agreement to develop In Situ Hybridization protocols for RNA and DNA targets in tissue using reagents provided by Vitro on Lunaphore’s rapid autostaining platform.

25 May 2018

Study uncovers mechanism underlying brain malformation linked to severe epilepsy

One of the most frequent causes of drug-resistant epilepsy, considered a difficult disease to control, is a brain malformation known as focal cortical dysplasia.

16 May 2018

Bio-Techne expands automation capabilities of popular RNAscope ISH technology

Bio-Techne has expanded the automation capabilities of its popular Advanced Cell Diagnostics -branded RNAscope in situ hybridization technology with the launch of several new and updated assays.

From Bio-Techne 18 Apr 2018

Oxford Gene Technology announces leadership changes

Oxford Gene Technology, The Molecular Genetics Company, has announced that on 1st April 2018 Dr John Anson who has been with the company since 2006 as EVP of R&D took over as CEO from Dr Mike Evans, who has become a non-executive director of OGT’s board.

From Oxford Gene Technology 10 Apr 2018

Researchers develop way to sequence entire fetal genome by modifying prenatal testing method

For the first time, researchers have developed a way to sequence the entire genome of a fetus by modifying the prenatal testing method known as amniocentesis.

16 Mar 2018