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Psychiatric comorbidities predict bipolar disorder in ADHD children

Psychiatric comorbidities predict bipolar disorder in ADHD children

Children with attention deficit/hyperactivity disorder who also have conduct disorder/oppositional defiant disorder or anxiety disorder are at an increased risk of developing bipolar disorder, research shows. [More]
Study examines benefits of IS technique in assessing effect of pollution on urban asthmatic children

Study examines benefits of IS technique in assessing effect of pollution on urban asthmatic children

For the firefighters and rescue workers conducting the rescue and cleanup operations at Ground Zero from September 2001 to May 2002, exposure to hazardous airborne particles led to a disturbing "WTC cough" -- obstructed airways and inflammatory bronchial hyperactivity -- and acute inflammation of the lungs. At the time, bronchoscopy, the insertion of a fiber optic bronchoscope into the lung, was the only way to obtain lung samples. But this method is highly invasive and impractical for screening large populations. [More]
Genetic variations may contribute to treatment-related cognitive problems in children with ALL

Genetic variations may contribute to treatment-related cognitive problems in children with ALL

Common variations in four genes related to brain inflammation or cells' response to damage from oxidation may contribute to the problems with memory, learning and other cognitive functions seen in children treated for acute lymphoblastic leukemia (ALL), according to a study led by researchers from Boston Children's Hospital, The Children's Hospital at Montefiore, and Dana-Farber/Boston Children's Cancer and Blood Disorders Center. [More]
SAFit-ligands provide foundation for novel treatment of stress-related psychiatric disorders

SAFit-ligands provide foundation for novel treatment of stress-related psychiatric disorders

The FK506-binding protein 51 (FKBP51) is an established risk factor for stress-related psychiatric disorders such as major depression. Drug discovery for FKBP51 has been hampered by the inability to pharmacologically differentiate against the very similar functional counterplayer FKBP52. [More]
Physical activity linked to children's brain and cognitive development, scholastic achievement

Physical activity linked to children's brain and cognitive development, scholastic achievement

Over the past thirty years, physical activity among children has declined markedly. The public health implications of this decline include a growing prevalence of obesity and chronic diseases such as diabetes and hypertension. A new issue of Monographs of the Society for Research in Child Development expands the focus to ask whether physical activity is also related to children's brain and cognitive development and achievement in school. [More]
Study examines rate of psychotropic medication prescribed to children in Kentucky

Study examines rate of psychotropic medication prescribed to children in Kentucky

Researchers with the Child and Adolescent Health Research Design and Support Unit (CAHRDS Unit) at the University of Louisville have begun a study to examine one of Kentucky's most vexing children's health issues: the higher-than-average rate of psychotropic medication being prescribed to children in the Bluegrass State. [More]
Study shows how specific trauma changes into a state of generalized fear

Study shows how specific trauma changes into a state of generalized fear

"I can't get the memories out of my mind!... I am right back in Vietnam, in the middle of the monsoon season at my guard post. My hands are freezing, yet sweat pours from my entire body...I smell a damp sulfur smell. Suddenly I see what's left of my buddy Troy, his head on a bamboo platter, sent back to our camp by the Viet Cong." [More]
ADHD information on social media: an interview with Gemma Ryan

ADHD information on social media: an interview with Gemma Ryan

It came about through the implementation of another ADHD project called One Stop Shop, which is a collaborative project with Leicestershire Partnership NHS trust (LPT) and ADHD Solutions, a charitable support organization. [More]
Childhood affective features may guide adult psychiatric diagnosis

Childhood affective features may guide adult psychiatric diagnosis

Clinical features that can appear many years ahead of a psychiatric diagnosis may help doctors to predict whether patients will develop bipolar disorder or unipolar depression, say researchers. [More]
Special receptor signalling mediates astrocytic hyperactivity in  Alzheimer's disease mouse model

Special receptor signalling mediates astrocytic hyperactivity in Alzheimer's disease mouse model

It has long been known that astrocytes change their shapes as a consequence of Alzheimer's. Cells located near the "plaques", as the protein deposits typical for this disease are called, grow in size and form additional extensions. [More]
New mouse model shows how mutated gene impairs neuronal development in individuals with autism

New mouse model shows how mutated gene impairs neuronal development in individuals with autism

Geneticists at Heidelberg University Hospital's Department of Molecular Human Genetics have used a new mouse model to demonstrate the way a certain genetic mutation is linked to a type of autism in humans and affects brain development and behavior. [More]
HLD-200 successfully meets primary endpoint in Phase III study

HLD-200 successfully meets primary endpoint in Phase III study

Highland Therapeutics Inc., a pharmaceutical company, today announced that its wholly owned subsidiary, Ironshore Pharmaceuticals & Development, Inc. has reported positive top-line results from its recently completed Phase III study. [More]
Mothers, teachers lack awareness about ADHD symptoms in tween girls

Mothers, teachers lack awareness about ADHD symptoms in tween girls

According to a new survey released today, nearly 50 percent of mothers of tween girls who have been diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD) reported that they had first attributed their daughters' behavior to "normal" adolescent struggles, and 59 percent reported that they initially hesitated to seek help from a doctor for their daughter. [More]
Mice may hold clues in development of ADHD, autism and bipolar disorder

Mice may hold clues in development of ADHD, autism and bipolar disorder

A darting mouse may hold an important clue in the development of Attention Deficit Hyperactivity Disorder (ADHD), autism and bipolar disorder, according to a study by a Vanderbilt University-led research team recently published in the Proceedings of the National Academy of Sciences. [More]
McLean Hospital lab explores use of stem cell therapy to treat epilepsy

McLean Hospital lab explores use of stem cell therapy to treat epilepsy

McLean Hospital and Harvard Stem Cell Institute scientists have new evidence that stem cell transplantation could be a worthwhile strategy to help epileptics who do not respond to anti-seizure drugs. [More]
Researchers discover link between seizures and migraines

Researchers discover link between seizures and migraines

Seizures and migraines have always been considered separate physiological events in the brain, but now a team of engineers and neuroscientists looking at the brain from a physics viewpoint discovered a link between these and related phenomena. [More]
Sleep problems very common among young children receiving treatment for psychiatric disorders

Sleep problems very common among young children receiving treatment for psychiatric disorders

John Boekamp, Ph.D., clinical director of the Pediatric Partial Hospital Program at Bradley Hospital recently led a study that found sleep difficulties - particularly problems with falling asleep - were very common among toddlers and preschool-aged children who were receiving clinical treatment for a wide range of psychiatric disorders. [More]

University of Derby wins award for collaborative social media campaign

The University of Derby has won an award at the inaugural East Midlands Innovation in Healthcare awards, for a collaborative social media campaign with Leicestershire Partnership NHS Trust and ADHD Solutions. [More]
Genetic risk for ADHD contributes to language, attention deficits in general population

Genetic risk for ADHD contributes to language, attention deficits in general population

Are deficits in attention limited to those with attention-deficit/hyperactivity disorder (ADHD) or is there a spectrum of attention function in the general population? [More]
Actavis seeks FDA approval to market generic version of Quillivant XR

Actavis seeks FDA approval to market generic version of Quillivant XR

Actavis plc today confirmed that it has filed an Abbreviated New Drug Application (ANDA) with the U.S. Food and Drug Administration seeking approval to market Methylphenidate Hydrochloride for Extended-release Oral Suspension, 5 mg/mL. Actavis' ANDA product is a generic version of Pfizer and Tris Pharma's Quillivant XR®, which is a central nervous system stimulant indicated for the treatment of Attention Deficit Hyperactivity Disorder. [More]