Hyperglycemia News and Research RSS Feed - Hyperglycemia News and Research

Hyperglycemia occurs when you have a higher than usual level of glucose in your blood. This can happen shortly after you have eaten a big meal and is not a problem if your glucose level returns to normal. Cells remove glucose from the blood in response toinsulin. If your pancreas doesn't make enough insulin, glucose can't enter the cells and remains in the blood. Blood glucose levels can also get too high if cells areunable to respond to insulin properly (insulinresistance). Without glucose, your cells are unable to make energy and can't function properly.
Newer class of diabetes medications may also improve cardiovascular health, researchers report

Newer class of diabetes medications may also improve cardiovascular health, researchers report

A newer class of medications used to control blood sugar levels in type 2 diabetics may also improve cardiovascular health, researchers from The Ohio State University Wexner Medical Center reported in a new meta-analysis presented yesterday at the American Society of Hypertension's Annual Scientific Meeting and Exposition. [More]

Study reveals that prolonged Dkk1 signaling can lead to fibrosis, stiffening of artery walls

The hardening of arteries is a hallmark of atherosclerosis, an often deadly disease in which plaques, excessive connective tissue, and other changes build up inside vessel walls and squeeze off the flow of oxygen-rich blood throughout the body. [More]
New therapeutic targets for reducing heart disease in people with type 1 diabetes

New therapeutic targets for reducing heart disease in people with type 1 diabetes

Type 1 (insulin-dependent) diabetes appears to increase the risk of heart disease, the leading cause of death among people with high blood sugar, partly by stimulating the production of calprotectin, a protein that sparks an inflammatory process that fuels the buildup of artery-clogging plaque. [More]

Boehringer Ingelheim Pharmaceuticals, Eli Lilly launch SGLT disease education initiative

Boehringer Ingelheim Pharmaceuticals, Inc. and Eli Lilly and Company today announced the launch of an educational campaign designed to provide healthcare professionals with a greater understanding of the role sodium glucose co-transporters play in maintaining blood sugar balance, or glucose homeostasis. [More]
Rhythm starts RM-131 Phase 2 clinical trial for treatment of chronic constipation

Rhythm starts RM-131 Phase 2 clinical trial for treatment of chronic constipation

Rhythm announced today the initiation of an additional Phase 2 clinical trial for RM-131, the company's novel ghrelin agonist, for the treatment of chronic constipation. Ghrelin is a peptide hormone produced in the stomach that stimulates gastrointestinal motility. [More]

Abbott recalls FreeStyle InsuLinx Blood Glucose Meters

Abbott today announced it is initiating a voluntary recall of FreeStyle InsuLinx Blood Glucose Meters in the United States. [More]

Researchers present data on ARQ 092 at 2013 AACR Annual Meeting

Researchers presented data today on ARQ 092, an AKT inhibitor in Phase 1 clinical development by ArQule, Inc. at the AACR Annual Meeting held in Washington, D.C., April 6-10, showing that this novel, oral agent inhibits the AKT pathway and has a manageable safety profile in an ongoing Phase 1 clinical trial. [More]
Joslin researchers identify role of dietary fat in patients with type 1 diabetes

Joslin researchers identify role of dietary fat in patients with type 1 diabetes

In a study of patients with type 1 diabetes, Joslin researchers found that dietary fat can affect glucose levels and insulin requirements. These findings, which appeared in the April edition of Diabetes Care, have major implications for the management of type 1 diabetes. [More]

Cognitive behavioral therapy brings relief to people with diabetic neuropathies, researchers find

Researchers at Boston University School of Medicine and VA Boston Healthcare System have found that cognitive behavioral therapy can help relieve pain for people with painful diabetic neuropathies. [More]
Otsuka receives FDA approval for ABILIFY MAINTENA to treat schizophrenia

Otsuka receives FDA approval for ABILIFY MAINTENA to treat schizophrenia

Otsuka Pharmaceutical Co., Ltd. (Otsuka) and H. Lundbeck A/S (Lundbeck) announced the U.S. Food and Drug Administration (FDA) has approved ABILIFY MAINTENA (aripiprazole) for extended- release injectable suspension, an intramuscular (IM) depot formulation indicated for the treatment of schizophrenia. [More]
Cardiometabolic risk prevention opportunity in early schizophrenia

Cardiometabolic risk prevention opportunity in early schizophrenia

esearchers have found that cardiometabolic risk in patients with schizophrenia is heightened in those with established disease, suggesting a need for early intervention in those presenting with their first episode. [More]
Study describes pharmacological action of TZDs directly on pancreas

Study describes pharmacological action of TZDs directly on pancreas

A scientific study published on the journal Diabetes, edited by the American Diabetes Association, describes for the first time the pharmacological action of thiazolidinediones (TZDs) —anti-diabetic drugs— directly on pancreas, the organ which produces insulin. [More]
Prediabetes associated with impaired lung function

Prediabetes associated with impaired lung function

Japanese researchers have found a significant association between prediabetes and impaired lung function. [More]

MannKind fourth quarter total operating expenses increase to $33.5 million

MannKind Corporation today reported financial results for the fourth quarter and year ended December 31, 2012. [More]
Single gene therapy session can cure diabetes

Single gene therapy session can cure diabetes

​Researchers from the Universitat Aut-noma de Barcelona (UAB), led by F-tima Bosch, have shown for the first time that it is possible to cure diabetes in large animals with a single session of gene therapy. As published this week in Diabetes, the principal journal for research on the disease, after a single gene therapy session, the dogs recover their health and no longer show symptoms of the disease. [More]

Metabolic syndrome risk factors prevalent in bipolar disorder

People who have bipolar disorder are at a high risk for developing the metabolic syndrome and related cardiovascular disorders, say researchers. [More]
Novartis receives FDA approval for Signifor injection to treat Cushing's disease

Novartis receives FDA approval for Signifor injection to treat Cushing's disease

The U.S. Food and Drug Administration today approved Signifor (pasireotide diaspartate) injection for the treatment of Cushing's disease patients who cannot be helped through surgery. [More]
Paroxetine could treat vascular complications of diabetes

Paroxetine could treat vascular complications of diabetes

University of Texas Medical Branch at Galveston researchers have discovered that the commonly used antidepressant drug paroxetine could also become a therapy for the vascular complications of diabetes. [More]
FDA approves Novartis Signifor injection for treatment of Cushing's disease

FDA approves Novartis Signifor injection for treatment of Cushing's disease

Novartis announced today that the US Food and Drug Administration (FDA) has approved Signifor (pasireotide) injection for the treatment of adult patients with Cushing's disease for whom pituitary surgery is not an option or has not been curative. [More]
Janssen receives FDA approval for ZYTIGA to treat metastatic castration-resistant prostate cancer

Janssen receives FDA approval for ZYTIGA to treat metastatic castration-resistant prostate cancer

Janssen announced today that the U.S. Food and Drug Administration (FDA) has approved a broader indication for the oral, once-daily medication ZYTIGA (abiraterone acetate). [More]